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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SRSF6 Gene

protein-coding   GIFtS: 57
GCID: GC20P042087

serine/arginine-rich splicing factor 6

(Previous names: splicing factor, arginine/serine-rich 6 )
(Previous symbol: SFRS6)
 Explore 9 diseases affiliated with
SRSF6 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SRSF6    

Aliases
for SRSF6 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Serine/Arginine-Rich Splicing Factor 61 2     Splicing Factor, Arginine/Serine-Rich 61 3
SFRS61 2 3     Pre-MRNA-Splicing Factor SRP552 3
SRP551 2 3     Splicing Factor, Arginine/Serine-Rich, 55 KDa2
B521 2     SR Splicing Factor 62

External Ids:    HGNC: 107881   Entrez Gene: 64312   Ensembl: ENSG000001241937   OMIM: 6019445   UniProtKB: Q132473   
ORGUL members:         
NONCODE:n409625    

Export aliases for SRSF6 gene to outside databases

Previous GC identifer: GC20P038822


Summaries
for SRSF6 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SRSF6:
The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative
splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and
modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In
addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this
gene.(provided by RefSeq, Sep 2010)

UniProtKB/Swiss-Prot: SRSF6_HUMAN, Q13247
Function: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses
the splicing of MAPT/Tau exon 10

Gene Wiki entry for SRSF6 (SFRS6)


Genomic Views
for SRSF6 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SRSF6
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SRSF6 promoter sequence
   Search SABiosciences Chromatin IP Primers for SRSF6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRSF6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q12-q13.1   Ensembl cytogenetic band:  20q13.11   HGNC cytogenetic band: 20q12-q13.1

SRSF6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRSF6 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P042087:  view genomic region     (about GC identifiers)

Start:
 42,086,504 bp from pter      End:
 42,092,245 bp from pter
Size:
 5,742 bases      Orientation:
 plus strand

Proteins
for SRSF6 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SRSF6_HUMAN, Q13247 (See protein sequence)
Recommended Name: Serine/arginine-rich splicing factor 6  
Size: 344 amino acids; 39587 Da
Subunit: Binds SREK1/SFRS12
Subcellular location: Nucleus
Secondary accessions: B7Z6J3 E1P5W6 Q13244 Q13245 Q96J06 Q9UJB8 Q9Y3N7
Alternative splicing: 3 isoforms:  Q13247-1   Q13247-2   Q13247-3   

Explore the universe of human proteins at neXtProt for SRSF6: NX_Q13247

Post-translational modifications:

  • Extensively phosphorylated on serine residues in the RS domain (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13247

    • SRSF6 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006266.2  
    ENSEMBL proteins: 
     ENSP00000244020   ENSP00000433544  
    Reactome Protein details: Q13247
    Human Recombinant Protein Products: 
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SRSF6

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005730NOT nucleolus IDA--


    SRSF6 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SRSF6

    Protein Domains /
    Families
    for SRSF6 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SRSF6 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000504 RRM_dom
     IPR012677 Nucleotide-bd_a/b_plait

    Graphical View of Domain Structure for InterPro Entry Q13247

    ProtoNet protein and cluster: Q13247

    1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: SRSF6_HUMAN, Q13247
    Similarity: Belongs to the splicing factor SR family
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    Function
    for SRSF6 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SRSF6_HUMAN, Q13247
    Function: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses
    the splicing of MAPT/Tau exon 10

    miRNA
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    hsa-miR-193a-3p hsa-miR-642a hsa-miR-371-5p hsa-miR-877* hsa-miR-629* hsa-miR-298 hsa-miR-3613-3p hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmid: SRSF6 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003723RNA binding IEA--


    SRSF6 for ontologies           About GeneDecksing



    Pathways & Interactions
    for SRSF6 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1mRNA Splicing - Major Pathway
    		mRNA Splicing1.00
    		mRNA processing0.48
    		mRNA Splicing - Major Pathway1.00
    		mRNA Splicing - Minor Pathway0.40
    		Processing of Capped Intron-Containing Pre-mRNA0.96
    		Spliceosome0.31
    		mRNA Processing0.82
    2RNA Polymerase II Transcription Termination
    		RNA Polymerase II Transcription Termination1.00
    		Post-Elongation Processing of Intron-Containing pre-mRNA0.79
    		Post-Elongation Processing of the Transcript1.00
    		mRNA 3'-end processing0.79
    		Cleavage of Growing Transcript in the Termination Region 1.00
    3Transcription
    		Transcription1.00
    		RNA Polymerase II Transcription0.69
    4Transport of Mature Transcript to Cytoplasm
    		Transport of Mature Transcript to Cytoplasm1.00
    		Transport of Mature mRNA derived from an Intron-Containing Transcript0.85
    5Generic Transcription Pathway
    		Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for SRSF6 
        mRNA processing

    5/15        Reactome Pathways for SRSF6 (see all 15)
        Transport of Mature mRNA derived from an Intron-Containing Transcript
    mRNA Splicing - Major Pathway
    Transport of Mature Transcript to Cytoplasm
    mRNA Splicing
    RNA Polymerase II Transcription


    1         Kegg Pathway  (Kegg details for SRSF6):
        Spliceosome


    SRSF6 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SRSF6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/649 Interacting proteins for SRSF6 (Q132472, 3 ENSP000002440204) via UniProtKB, MINT, STRING, and/or I2D (see all 649)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SF3A2Q154282, 3, ENSP000002214944MINT-5205746 I2D: score=1 STRING: ENSP00000221494
    SRRM1Q8IYB32, 3, ENSP000003262614MINT-7945693 I2D: score=1 STRING: ENSP00000326261
    PKP3Q9Y4462, 3MINT-7945693 I2D: score=1 
    SF3B4Q154272, ENSP000002716284MINT-7945693 MINT-8333834 STRING: ENSP00000271628
    SRSF4Q081702, 3, ENSP000003629004MINT-67374 I2D: score=5 STRING: ENSP00000362900
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0006366transcription from RNA polymerase II promoter TAS--
    GO:0006369termination of RNA polymerase II transcription TAS--
    GO:0006376mRNA splice site selection TAS7556075
    GO:0006406mRNA export from nucleus TAS--


    SRSF6 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SRSF6 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SRSF6
    Search CenterWatch for drugs/clinical trials and news about SRSF6 

    Transcripts
    for SRSF6 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SRSF6 gene: 
    NM_006275.5  

    Unigene Cluster for SRSF6:

    Serine/arginine-rich splicing factor 6
    Hs.743979  [show with all ESTs]
    Unigene Representative Sequence: NR_034009
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000244020(uc010zwg.2) ENST00000483871(uc002xki.3)

    miRNA
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    hsa-miR-193a-3p hsa-miR-642a hsa-miR-371-5p hsa-miR-877* hsa-miR-629* hsa-miR-298 hsa-miR-3613-3p hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmid: SRSF6 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AB208976.1 AB451251.1 AB451375.1 AK291203.1 AK300411.1 AL110214.1 BC006832.2 NR_034009.1 
    U30883.1 

    24/27 DOTS entries (see all 27):

    DT.97854866  DT.92409366  DT.448577  DT.97854864  DT.100784554  DT.95370090  DT.95370104  DT.100784556 
    DT.120805126  DT.95370098  DT.95370101  DT.100883699  DT.101961741  DT.86852259  DT.91840278  DT.91984878 
    DT.92455309  DT.95370105  DT.100038540  DT.100740045  DT.100843141  DT.100883692  DT.120910051  DT.91769129 

    24/413 AceView cDNA sequences (see all 413):

    AA104026 AI984302 CA431262 BM969760 AA171640 BE218164 BG479193 AV704620 
    W84315 CB151393 CB267483 AA025088 CR606848 BP334718 CR605163 Z40991 
    BM788391 CB129500 CD622297 BU681811 AA884249 BM999875 AL700260 BG566261 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SRSF6 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8
    SP1:                                -                 -     -                                                   
    SP2:                                -     -     -     -     -                                                   
    SP3:                                -     -     -     -     -                             -     -     -         
    SP4:                                -     -           -     -                                                   
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for SRSF6

    Expression
    for SRSF6 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SRSF6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCGTAGTGCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SRSF6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SRSF6

    SOURCE GeneReport for Unigene cluster: Hs.743979
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    In Situ
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    Orthologs
    for SRSF6 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SRSF6 gene from 9/28 species (see all 28)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Srsf61 , 5 serine/arginine-rich splicing factor 61, 5 89.38(n)1
    97.64(a)1    		   2 (83.87 cM)5
    679961  NM_026499.41  NP_080775.31 
     1629315285 
    chicken
    (Gallus gallus)    		 Aves SRSF61 serine/arginine-rich splicing factor 6 79.98(n)
    91.55(a)    		   419116  NM_001030843.2  NP_001026014.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SRSF66
    		 --
    		 87(a)
    		 1 ↔ 1
    		 GL343365.1(501672-510157)
    African clawed frog
    (Xenopus laevis)    		 Amphibia b52-prov2 splicing factor, arginine/serine-rich 6 73.58(n)    BC044265.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BC055238.12   -- 79.95(n)    BC055238.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta B521 B52 57.76(n)
    66.35(a)    		   41670  NM_176488.2  NP_788665.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea rsp-11 Protein RSP-1 53.64(n)
    58.1(a)    		   174748  NM_064041.3  NP_496442.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons RS2Z336
    At-RS2Z6
    		 arginine/serine-rich zinc knuckle-containing prote...
    RNA recognition motif and CCHC-type zinc finger do...
    		 20(a)
    19(a)
    		 possible ortholog
    possible ortholog
    		 2(15670147-15672700)
    3(19834343-19837088)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 4)    		 splicing factor, arginine/serine-rich, putative, e...
    splicing factor, arginine/serine-rich 7, putative,...
    (see all 4)    		 18(a)
    17(a)
    (see all 4)    		 possible ortholog
    possible ortholog
    (see all 4)    		 1(2984356-2988299)
    5(1045861-1049349)


    ENSEMBL Gene Tree for SRSF6 (if available)
    TreeFam Gene Tree for SRSF6 (if available) 

    Paralogs
    for SRSF6 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SRSF6 gene
    LOC1009966572  SRSF42  SRSF122  SRSF102  SRSF92  SRSF52  SRSF22  SRSF72  
    SRSF12  SRSF32  
    8 SIMAP similar genes for SRSF6 using alignment to 2 protein entries:     SRSF6_HUMAN (see all proteins):
    SFRS6    SRSF4    SFRS4    SRSF5    SFRS5    SRSF1
    SRSF2    SRSF9

    SRSF6 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for SRSF6
    PGOHUM00000236934 PGOHUM00000241733 PGOHUM00000241734


    Genomic Variants
    for SRSF6 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/174 NCBI SNPs in SRSF6 are shown (see all 174)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1508047001,2
    		--42084809(+) AGGTTG/TCAGGG 2 -- us2k10--------
    rs1921813101,2
    		--42084837(+) GACATA/GGACAT 2 -- us2k10--------
    rs1400214181,2
    		--42084883(+) AAGAGA/GTGAAG 2 -- us2k10--------
    rs754644991,2
    		F,--42084932(+) TTTCCC/TGTCTA 2 -- us2k11Minor allele frequency- T:0.08NA 120
    rs1837922831,2
    		--42085119(+) AACCCA/GCTCGG 2 -- us2k10--------
    rs1892055101,2
    		--42085140(+) ACGCTG/TCGGAA 2 -- us2k10--------
    rs1419883131,2
    		--42085156(+) GTTCTC/TTCCTT 2 -- us2k10--------
    rs1922793911,2
    		--42085188(+) TTGTCA/GCCCAG 2 -- us2k10--------
    rs1463196291,2
    		--42085189(+) TGTCAC/TCCAGG 2 -- us2k10--------
    rs1837948241,2
    		--42085202(+) GGAGTA/GCAGTG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for SRSF6 (42086504 - 42092245 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SRSF6: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SRSF6 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SRSF6 for disorders           About GeneDecksing

    OMIM gene information: 601944    OMIM disorders: --

    9 diseases for SRSF6:    About MalaCards
    metastasis efficiency    frontotemporal dementia    familial hypercholesterolemia    progeria
    hypercholesterolemia    dementia    schizophrenia    immunodeficiency
    malaria

    1 disease from the University of Copenhagen DISEASES database for SRSF6:
    Denys-Drash syndrome
    Human Genome Epidemiology (HuGE) Navigator: SRSF6 (3 documents)

    Export disorders for SRSF6 gene to outside databases

    Publications
    for SRSF6 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SRSF6 gene, integrated from 9 sources (see all 81):
    (articles sorted by number of sources associating them with SRSF6)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. (PubMed id 7556075)1, 2, 3, 9 Screaton G.R.... Krainer A.R. (1995)
    2. A rational nomenclature for serine/arginine-rich prot ein splicing factors (SR proteins). (PubMed id 20516191)1, 3 Manley J.L. and Krainer A.R. (2010)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. (PubMed id 15009664)1, 2 Wang J....Andreadis A. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    7. Identification and characterization of a novel serine-arginine-rich splicing regulatory protein. (PubMed id 10757789)1, 2 Barnard D.C. and Patton J.G. (2000)
    8. SR proteins: a conserved family of pre-mRNA splicing factors. (PubMed id 1577277)1, 2 Zahler A.M.... Roth M.B. (1992)
    9. SRp55 is a regulator of calcitonin/CGRP alternative RNA splicing. (PubMed id 12549914)1, 9 Tran Q. and Roesser J.R. (2003)
    10. Specific binding of an exonic splicing enhancer by the pre-mRNA splicing factor SRp55. (PubMed id 9436904)1, 9 Nagel R.J....Zahler A.M. (1998)

    External Searches for SRSF6 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing SRSF6 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6431 HGNC: 10788 AceView: SFRS6 Ensembl:ENSG00000124193 euGenes: HUgn6431
    ECgene: SRSF6 Kegg: 6431 H-InvDB: SRSF6

    Other Databases showing SRSF6 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SRSF6 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SRSF6 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SRSF6 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SRSF6 gene:
    Search GeneIP for patents involving SRSF6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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