Aliases for SRSF5 Gene
External Ids for SRSF5 Gene
Previous HGNC Symbols for SRSF5 Gene
Previous GeneCards Identifiers for SRSF5 Gene
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for SRSF5 Gene
SRSF5 (Serine And Arginine Rich Splicing Factor 5) is a Protein Coding gene. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and RNA Polymerase II Transcription Termination. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is SRSF4.
UniProtKB/Swiss-Prot for SRSF5 Gene
Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.