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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SRSF4 Gene

protein-coding   GIFtS: 54
GCID: GC01M029474

serine/arginine-rich splicing factor 4

(Previous names: splicing factor, arginine/serine-rich 4 )
(Previous symbol: SFRS4)
 Explore 4 diseases affiliated with
SRSF4 via our new
 Human Malady Compendium 
Biological research products
for SRSF4
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Serine/Arginine-Rich Splicing Factor 41 2     Pre-MRNA-Splicing Factor SRP752 3
Splicing Factor, Arginine/Serine-Rich 41 2 3     SRP001LB2 3
SFRS41 2 3     SR Splicing Factor 42
SRP751 2 3     

External Ids:    HGNC: 107861   Entrez Gene: 64292   Ensembl: ENSG000001163507   OMIM: 6019405   UniProtKB: Q081703   

Export aliases for SRSF4 gene to outside databases

Previous GC identifer: GC01M027727


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SRSF4:
This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in
mRNA processing. (provided by RefSeq, Feb 2009)

UniProtKB/Swiss-Prot: SRSF4_HUMAN, Q08170
Function: Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of
MAPT/Tau exon 10

Gene Wiki entry for SRSF4 (SFRS4)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004610.19  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SRSF4
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSRSF4 promoter sequence
   Search SABiosciences Chromatin IP Primers for SRSF4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRSF4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.3   Ensembl cytogenetic band:  1p35.3   HGNC cytogenetic band: 1p35.3

SRSF4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRSF4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M029474:  view genomic region     (about GC identifiers)

Start:
29,474,250 bp from pter      End:
29,508,637 bp from pter
Size:
34,388 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SRSF4_HUMAN, Q08170 (See protein sequence)
Recommended Name: Serine/arginine-rich splicing factor 4  
Size: 494 amino acids; 56678 Da
Subunit: Found in a pre-mRNA splicing complex with SRSF4/SFRS4, SRSF5/SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2.
Interacts with PNN
Subcellular location: Nucleus speckle
Secondary accessions: Q5VXP1 Q9BUA4 Q9UEB5

Explore the universe of human proteins at neXtProt for SRSF4: NX_Q08170

Post-translational modifications:

  • Extensively phosphorylated on serine residues in the RS domain1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q08170

  • SRSF4 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005617.2  
    ENSEMBL proteins: 
     ENSP00000362900   ENSP00000444600  
    Reactome Protein details: Q08170
    Human Recombinant Protein Products: 
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    Uscn Proteins for SRSF4

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS8321209
    GO:0005654nucleoplasm TAS--
    GO:0016607nuclear speck IEA--


    SRSF4 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SRSF4 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000504 RRM_dom
     IPR012677 Nucleotide-bd_a/b_plait

    Graphical View of Domain Structure for InterPro Entry Q08170

    ProtoNet protein and cluster: Q08170

    1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: SRSF4_HUMAN, Q08170
    Similarity: Belongs to the splicing factor SR family
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: SRSF4_HUMAN, Q08170
    Function: Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of
    MAPT/Tau exon 10

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    hsa-miR-3163 hsa-miR-548p hsa-miR-607 hsa-miR-3688-3p hsa-miR-509-5p hsa-miR-483-5p hsa-miR-139-5p hsa-miR-4261
    SwitchGear 3'UTR luciferase reporter plasmidSRSF4 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--


    SRSF4 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for SRSF4:
     Cell division defect  Increased G2M DNA content 

    Animal Models:
         8 MGI mutant phenotypes (inferred from 1 allele(MGI details for Srsf4):
     behavior/neurological  growth/size  hematopoietic system  homeostasis/metabolism  immune system 
     integument  other  vision/eye 

    SRSF4 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1mRNA Splicing - Major Pathway
    mRNA Splicing1.00
    mRNA Processing0.82
    mRNA Splicing - Major Pathway1.00
    mRNA processing0.48
    Processing of Capped Intron-Containing Pre-mRNA0.96
    Spliceosome0.31
    2RNA Polymerase II Transcription Termination
    RNA Polymerase II Transcription Termination1.00
    Post-Elongation Processing of Intron-Containing pre-mRNA0.79
    Post-Elongation Processing of the Transcript1.00
    mRNA 3'-end processing0.79
    Cleavage of Growing Transcript in the Termination Region 1.00
    3Transcription
    Transcription1.00
    RNA Polymerase II Transcription0.69
    4Transport of Mature Transcript to Cytoplasm
    Transport of Mature Transcript to Cytoplasm1.00
    Transport of Mature mRNA derived from an Intron-Containing Transcript0.85
    5Generic Transcription Pathway
    Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for SRSF4 
        mRNA processing

    5/14        Reactome Pathways for SRSF4 (see all 14)
        Transport of Mature mRNA derived from an Intron-Containing Transcript
    mRNA Splicing - Major Pathway
    Transport of Mature Transcript to Cytoplasm
    mRNA Splicing
    RNA Polymerase II Transcription


    1         Kegg Pathway  (Kegg details for SRSF4):
        Spliceosome


    SRSF4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SRSF4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/641 Interacting proteins for SRSF4 (Q081702, 3 ENSP000003629004) via UniProtKB, MINT, STRING, and/or I2D (see all 641)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SF3A2Q154282, 3, ENSP000002214944MINT-5205755 MINT-7947479 I2D: score=1 STRING: ENSP00000221494
    FUSP356372, 3, ENSP000002541084MINT-7947479 I2D: score=2 STRING: ENSP00000254108
    SRRM1Q8IYB32, 3, ENSP000003262614MINT-7947479 I2D: score=1 STRING: ENSP00000326261
    HAP1P542572, 3MINT-64068 I2D: score=4 
    RNPS1Q152872, 3, ENSP000003158594MINT-8337893 I2D: score=1 STRING: ENSP00000315859
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000375RNA splicing, via transesterification reactions TAS8321209
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0006366transcription from RNA polymerase II promoter TAS--
    GO:0006369termination of RNA polymerase II transcription TAS--
    GO:0006397mRNA processing TAS8321209


    SRSF4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SRSF4
    Search CenterWatch for drugs/clinical trials and news about SRSF4 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SRSF4 gene: 
    NM_005626.4  

    Unigene Cluster for SRSF4:

    Serine/arginine-rich splicing factor 4
    Hs.469970  [show with all ESTs]
    Unigene Representative Sequence: NM_005626
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373795(uc001bro.3 uc010ofy.2 uc009vtp.2) ENST00000466448
    ENST00000497015 ENST00000477193 ENST00000489898 ENST00000472353 ENST00000546138


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    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate SRSF4 (see all 10):
    hsa-miR-3163 hsa-miR-548p hsa-miR-607 hsa-miR-3688-3p hsa-miR-509-5p hsa-miR-483-5p hsa-miR-139-5p hsa-miR-4261
    SwitchGear 3'UTR luciferase reporter plasmidSRSF4 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AB073890.1 AK223444.1 AK291509.1 AK293706.1 AK310528.1 BC002781.2 BT007415.1 L14076.1 

    24 DOTS entries:

    DT.91866269  DT.447026  DT.409564  DT.100796314  DT.101970353  DT.121359887  DT.100796309  DT.100796313 
    DT.91761381  DT.92070418  DT.121359879  DT.92059619  DT.121359873  DT.121359891  DT.121359892  DT.121359908 
    DT.97776365  DT.97803877  DT.100729827  DT.75161147  DT.92020068  DT.95321068  DT.97820511  DT.99995282 

    24/364 AceView cDNA sequences (see all 364):

    AI885764 BQ937431 BX345476 CR594929 AA429446 BM676150 BX099566 BI492812 
    CA446139 BF931267 AW078587 CA446677 AA568697 BQ188658 AI458849 BF796441 
    BM972684 AA600149 AA055897 AI066565 AI423362 BM724306 AI921231 BF515453 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SRSF4 (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c
    SP1:        -     -     -     -     -                 -     -     -     -                       -                           
    SP2:              -     -     -     -                 -     -     -     -                       -                           
    SP3:              -     -     -     -                 -     -     -     -                       -     -                     
    SP4:                                                                                            -                           
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for SRSF4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SRSF4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCCACAGTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SRSF4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SRSF4

    SOURCE GeneReport for Unigene cluster: Hs.469970
        SABiosciences Custom PCR Arrays for SRSF4
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SRSF4 gene from 6/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves SRSF46
    Uncharacterized protein
    79(a)
    1 ↔ 1
    23(3042610-3049604)
    zebrafish
    (Danio rerio)
    Actinopterygii wufb37e022 wufb37e02 78.36(n)   321872  BC046895.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta B526
    B52
    50(a)
    1 → many
    3R(9487022-9492613)
    worm
    (Caenorhabditis elegans)
    Secernentea rsp-21 Protein RSP-2 52.04(n)
    52.67(a)
      174747  NM_064040.5  NP_496441.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons At-RS2Z6
    RS2Z336
    RNA recognition motif and CCHC-type zinc finger do...
    arginine/serine-rich zinc knuckle-containing prote...
    20(a)
    20(a)
    possible ortholog
    possible ortholog
    3(19834343-19837088)
    2(15670147-15672700)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 4)
    splicing factor, arginine/serine-rich, putative, e...
    splicing factor, arginine/serine-rich 7, putative,...
    (see all 4)
    19(a)
    18(a)
    (see all 4)
    possible ortholog
    possible ortholog
    (see all 4)
    1(2984356-2988299)
    5(1045861-1049349)


    ENSEMBL Gene Tree for SRSF4 (if available)
    TreeFam Gene Tree for SRSF4 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SRSF4 gene
    LOC1009966572  SRSF122  SRSF102  SRSF92  SRSF52  SRSF22  SRSF72  SRSF12  
    SRSF62  SRSF32  
    10 SIMAP similar genes for SRSF4 using alignment to 2 protein entries:     SRSF4_HUMAN (see all proteins):
    SFRS4    SFRS6    SRSF6    SFRS5    SRSF5    SRSF9
    RALY    SFRS3    SRSF1    IGF2BP3

    SRSF4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/582 NCBI SNPs in SRSF4 are shown (see all 582    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs635627601,2
    C--27754943(+) ACTTT-/AAAAAA 1 -- int12Minor allele frequency- A:0.00NA CSA 4
    rs28196081,2
    C,F,H,--29473838(-) ATCACC/GCATCT 1 -- ds500114Minor allele frequency- G:0.49NA WA CSA EA 507
    rs24527821,2
    C,A,H,--29474134(-) GTTTGG/TGAGGC 1 -- ds500112Minor allele frequency- T:0.32NA WA CSA EA 374
    rs1905774201,2
    --29474165(+) GCCACC/TGTGCC 1 -- ds50010--------
    rs1814601081,2
    --29474174(+) CCCGGC/TCTACA 1 -- ds50010--------
    rs11308461,2
    C,A,H--29474358(-) aaaaaG/Aaaaag 1 -- ut313Minor allele frequency- A:0.00MN NS NA 410
    rs1859951741,2
    --29474415(+) GTTTAC/TTTCCT 1 -- ut310--------
    rs1181761961,2
    C,F,--29474544(+) ACATCG/AAAGGG 1 -- ut311Minor allele frequency- A:0.03EA 120
    rs1884101161,2
    C,--29474893(+) CTTCTC/TGGGTA 1 -- ut310--------
    rs2009873511,2
    --29474959(+) GGGAGC/GGCGAT 2 P R mis10--------

    HapMap Linkage Disequilibrium report for SRSF4 (29474250 - 29508637 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SRSF4: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SRSF4 for disorders           About GeneDecksing

    OMIM gene information: 601940    OMIM disorders: --

    4 diseases for SRSF4:    About MalaCards
    frontotemporal dementia    dementia    t lymphocyte deficiency    malaria


    Export disorders for SRSF4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SRSF4 gene, integrated from 9 sources (see all 47):
    (articles sorted by number of sources associating them with SRSF4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human SR proteins and isolation of a cDNA encoding SRp75. (PubMed id 8321209)1, 2, 3 Zahler A.M.... Roth M.B. (1993)
    2. Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. (PubMed id 14578391)1, 2, 9 Zimowska G.... Sugrue S.P. (2003)
    3. A rational nomenclature for serine/arginine-rich prot ein splicing factors (SR proteins). (PubMed id 20516191)1, 3 Manley J.L. and Krainer A.R. (2010)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    6. Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. (PubMed id 15009664)1, 2 Wang J....Andreadis A. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. A coactivator of pre-mRNA splicing. (PubMed id 9531537)1, 2 Blencowe B.J.... Sharp P.A. (1998)
    9. SR proteins: a conserved family of pre-mRNA splicing factors. (PubMed id 1577277)1, 2 Zahler A.M.... Roth M.B. (1992)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6429 HGNC: 10786 AceView: SFRS4 Ensembl:ENSG00000116350 euGenes: HUgn6429
    ECgene: SRSF4 Kegg: 6429 H-InvDB: SRSF4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SRSF4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SRSF4 gene:
    Search GeneIP for patents involving SRSF4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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