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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SRSF11 Gene

protein-coding   GIFtS: 55
GCID: GC01P070672

Serine/Arginine-Rich Splicing Factor 11

(Previous names: splicing factor, arginine/serine-rich 11)
(Previous symbol: SFRS11)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Serine/Arginine-Rich Splicing Factor 111 2     p542 3
Splicing Factor, Arginine/Serine-Rich 111 2 3     NET22
SFRS111 2 3     dJ677H15.22
SR Splicing Factor 111 2     Splicing Factor P542
Arginine-Rich 54 KDa Nuclear Protein2 3     

External Ids:    HGNC: 107821   Entrez Gene: 92952   Ensembl: ENSG000001167547   OMIM: 6020105   UniProtKB: Q055193   

Export aliases for SRSF11 gene to outside databases

Previous GC identifer: GC01P068782


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SRSF11 Gene:
This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in
pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and
immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in
multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found
on chromosome 12.(provided by RefSeq, Sep 2010)

GeneCards Summary for SRSF11 Gene: 
SRSF11 (serine/arginine-rich splicing factor 11) is a protein-coding gene. Diseases associated with SRSF11 include frontotemporal dementia, and dementia, and among its related super-pathways are Post-Elongation Processing of Intron-Containing pre-mRNA and mRNA Processing. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is SREK1.

UniProtKB/Swiss-Prot: SRS11_HUMAN, Q05519
Function: May function in pre-mRNA splicing

Gene Wiki entry for SRSF11 (SFRS11) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SRSF11
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): SRSF11 promoter sequence
   Search SABiosciences Chromatin IP Primers for SRSF11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRSF11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31   Ensembl cytogenetic band:  1p31.1   HGNC cytogenetic band: 1p31.1

SRSF11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRSF11 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P070672:  view genomic region     (about GC identifiers)

Start:
70,671,365 bp from pter      End:
70,718,735 bp from pter
Size:
47,371 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SRS11_HUMAN, Q05519 (See protein sequence)
Recommended Name: Serine/arginine-rich splicing factor 11  
Size: 484 amino acids; 53542 Da
Subunit: Interacts with PUF60
Subcellular location: Nucleus. Note=Colocalizes with spliceosome components
Secondary accessions: Q5T758 Q8IWE6
Alternative splicing: 2 isoforms:  Q05519-1   Q05519-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SRSF11: NX_Q05519

Explore proteomics data for SRSF11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q05519

  • SRSF11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SRSF11 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001177916.1  NP_004759.1  

    ENSEMBL proteins: 
     ENSP00000359989   ENSP00000359988   ENSP00000474372   ENSP00000378568   ENSP00000474149  
     ENSP00000359987   ENSP00000384357   ENSP00000405120   ENSP00000411159  
    Reactome Protein details: Q05519
    Human Recombinant Protein Products for SRSF11: 
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    Cloud-Clone Corp. Proteins for SRSF11 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005730NOT nucleolus IDA--

    SRSF11 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RBM: RNA binding motif (RRM) containing
    SRSF: Serine/arginine-rich splicing factors

    2 InterPro protein domains:
     IPR000504 RRM_dom
     IPR012677 Nucleotide-bd_a/b_plait

    Graphical View of Domain Structure for InterPro Entry Q05519

    ProtoNet protein and cluster: Q05519

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: SRS11_HUMAN, Q05519
    Similarity: Belongs to the splicing factor SR family
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    SRSF11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SRS11_HUMAN, Q05519
    Function: May function in pre-mRNA splicing

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0005515protein binding IPI--
         
    SRSF11 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SRSF11 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase II Transcription Termination
    RNA Polymerase II Transcription Termination0.79
    Post-Elongation Processing of the Transcript0.79
    Post-Elongation Processing of Intron-Containing pre-mRNA0.79
    mRNA 3'-end processing0.79
    Cleavage of Growing Transcript in the Termination Region 0.79
    2mRNA Splicing - Major Pathway
    Processing of Capped Intron-Containing Pre-mRNA0.85
    mRNA Splicing - Major Pathway0.82
    mRNA Processing0.85
    mRNA Splicing0.82
    3Transport of Mature Transcript to Cytoplasm
    Transport of Mature Transcript to Cytoplasm0.85
    Transport of Mature mRNA derived from an Intron-Containing Transcript0.85
    4Transcription
    Transcription0.69
    RNA Polymerase II Transcription0.69
    5Generic Transcription Pathway
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/14        Reactome Pathways for SRSF11 (see all 14)
        Transport of Mature mRNA derived from an Intron-Containing Transcript
    mRNA Splicing - Major Pathway
    Transport of Mature Transcript to Cytoplasm
    mRNA Splicing
    RNA Polymerase II Transcription



    SRSF11 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SRSF11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/704 Interacting proteins for SRSF11 (Q055191, 2, 3 ENSP000003599884) via UniProtKB, MINT, STRING, and/or I2D (see all 704)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ETS1P149211, 3, ENSP000003764364EBI-1051785,EBI-913209 I2D: score=1 STRING: ENSP00000376436
    PUF60Q9UHX12, 3, ENSP000003220164MINT-7945693 I2D: score=4 STRING: ENSP00000322016
    SRSF1Q079552, 3, ENSP000002589624MINT-7945693 I2D: score=3 STRING: ENSP00000258962
    SRSF2Q011302, 3, ENSP000003508774MINT-7945693 I2D: score=3 STRING: ENSP00000350877
    U2AF2P263682, 3, ENSP000003078634MINT-7945693 I2D: score=3 STRING: ENSP00000307863
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0006366transcription from RNA polymerase II promoter TAS--
    GO:0006369termination of RNA polymerase II transcription TAS--
    GO:0006397mRNA processing TAS1896467
    GO:0006406mRNA export from nucleus TAS--

    SRSF11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SRSF11 (SRS11)

    Search CenterWatch for drugs/clinical trials and news about SRSF11 / SRS11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SRSF11 gene (2 alternative transcripts): 
    NM_001190987.1  NM_004768.3  

    Unigene Cluster for SRSF11:

    Serine/arginine-rich splicing factor 11
    Hs.479693  [show with all ESTs]
    Unigene Representative Sequence: BX640645
    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000370951(uc009wbi.3) ENST00000463877 ENST00000370950(uc001det.3 uc001des.3)
    ENST00000475204 ENST00000395136(uc001deu.2) ENST00000473950 ENST00000469170
    ENST00000486667 ENST00000481648 ENST00000463116 ENST00000484162(uc001dev.3)
    ENST00000370949(uc001dew.3) ENST00000463859 ENST00000460795 ENST00000461935
    ENST00000489188 ENST00000405432 ENST00000436161
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    Additional mRNA sequence: 

    AB062486.1 AK300147.1 AK301670.1 AK310447.1 AK310666.1 AK311184.1 AL832279.1 BC002784.2 
    BC009840.2 BC017359.2 BC022815.1 BC032727.1 BC040436.1 BX537679.1 BX640645.1 BX641004.1 
    M74002.1 

    24/39 DOTS entries (see all 39):

    DT.441504  DT.219368  DT.101985035  DT.92458648  DT.95258238  DT.100875482  DT.219363  DT.100731211 
    DT.40276859  DT.92057476  DT.85104163  DT.97767765  DT.97856065  DT.121411784  DT.121411659  DT.95258218 
    DT.95258224  DT.95258244  DT.100677405  DT.100892579  DT.121411748  DT.121411759  DT.95258245  DT.100059238 

    24/648 AceView cDNA sequences (see all 648):

    AU131222 AW084230 AA312269 AI075888 AU118996 CB241000 AU138208 CR614713 
    BI334259 AI446378 AI339897 AI202900 BM315085 AI979172 CA313349 AI332345 
    AW572522 AI653970 BE887320 CB132307 AA923757 BX456885 NM_004768 AL532192 

    GeneLoc Exon Structure

    5/22 Alternative Splicing Database (ASD) splice patterns (SP) for SRSF11 (see all 22)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c ^ 11 ^ 12 ^
    SP1:                                      -                 -     -     -     -     -     -     -     -     -     -     -                                       
    SP2:                    -     -           -                 -     -     -     -     -     -     -     -     -     -     -                                       
    SP3:                    -     -     -     -                 -     -     -     -     -     -     -     -     -     -     -                                       
    SP4:                    -     -           -                 -     -     -     -     -     -     -     -     -     -     -                                       
    SP5:                                                                                                                    -                                       

    ExUns: 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for SRSF11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SRSF11 expression in normal human tissues (normalized intensities)      SRSF11 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGATGTACA
    SRSF11 Expression
    About this image


    SRSF11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/35 selected tissues (see all 35) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Blood (Hematopoietic System)    fully expand to see all 4 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             lung ; macrophages   
             bone marrow cd34+   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   

    See SRSF11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SRSF11

    SOURCE GeneReport for Unigene cluster: Hs.479693
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SRSF11 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Srsf111 , 5 serine/arginine-rich splicing factor 111, 5 87.93(n)1
    96.21(a)1
      3 (81.63 cM)5
    692071  NM_001093752.11  NP_001087221.11 
     1580104735 
    chicken
    (Gallus gallus)
    Aves SRSF111 serine/arginine-rich splicing factor 11 84(n)
    94.91(a)
      424714  NM_001031296.1  NP_001026467.1 
    lizard
    (Anolis carolinensis)
    Reptilia SRSF116
    Uncharacterized protein
    92(a)
    1 ↔ 1
    GL343328.1(1161225-1191929)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.348222 Xenopus laevis transcribed sequence with moderate similarity more 80.2(n)    CA971280.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb37g022 wufb37g02 73.71(n)   321886  BC044186.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(3)psg26
    Srp546
    (see all 6)
    Srp54
    (see all 6)
    4(a)
    31(a)
    (see all 6)
    possible ortholog
    many ↔ many
    (see all 6)
    3L(5576769-5583490)
    2L(9912911-9915044)
    worm
    (Caenorhabditis elegans)
    Secernentea rsp-76
    Y57G11C.96
    (see all 3)
    Protein Y57G11C.9, isoform b
    (see all 3)
    30(a)
    12(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    II(10659206-10662315)
    IV(14787168-14790841)


    ENSEMBL Gene Tree for SRSF11 (if available)
    TreeFam Gene Tree for SRSF11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SRSF11 gene
    SREK12  
    6 SIMAP similar genes for SRSF11 using alignment to 5 protein entries:     SRS11_HUMAN (see all proteins):
    SFRS11    DKFZp686P22142    DKFZp686D02116    DKFZp686M13204    SREK1    DKFZp667P103

    SRSF11 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SRSF11
    PGOHUM00000239698


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/799 SNPs in SRSF11 are shown (see all 799)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2021609551,2
    C--70673408(+) CGTTC-/TTTTTT 2 -- int10--------
    rs1916980471,2
    --70673494(+) ACCTCA/GAAATC 2 -- int10--------
    rs781483211,2
    C--70673549(+) CACACC/TACCAT 2 -- int10--------
    rs1816835981,2
    --70673692(+) AAGCAA/GTCCTT 2 -- int10--------
    rs1865329041,2
    --70673700(+) CTTCTA/GTCTGG 2 -- int10--------
    rs1452446361,2
    --70673820(+) TAAATA/GTTTCA 2 -- int10--------
    rs1491917951,2
    C--70673974(+) CATATA/GTAAGA 2 -- int10--------
    rs1123435891,2
    C--70674008(+) GTATG-/GTGT  
     
    /GTGTGT
    GTGTG
    4 -- int1 cds11CSA 2
    rs1416541851,2
    C--70674009(+) GTATG-/GT/   
      GTGTGT
    GTGTG
    4 -- int1 cds10--------
    rs46500321,2
    --70674017(+) tgtgtA/Gtgtgt 2 -- int10--------

    HapMap Linkage Disequilibrium report for SRSF11 (70671365 - 70718735 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SRSF11:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2671094CNV Deletion23128226
    nsv1343CNV Insertion18451855
    nsv870841CNV Loss21882294
    nsv871898CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602010    OMIM disorders: --

    4 diseases for SRSF11:    About MalaCards
    frontotemporal dementia    dementia    kaposi's sarcoma    sarcoma


    SRSF11 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: SRSF11 (0 documents)

    Export disorders for SRSF11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SRSF11 gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with SRSF11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Primary structure of a human arginine-rich nuclear protein that colocalizes with spliceosome components. (PubMed id 1896467)1, 2, 3, 9 Chaudhary N.... Blobel G. (1991)
    2. A rational nomenclature for serine/arginine-rich prot ein splicing factors (SR proteins). (PubMed id 20516191)1, 3 Manley J.L. and Krainer A.R. (2010)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. PUF60: a novel U2AF65-related splicing activity. (PubMed id 10606266)1, 2 Page-McCaw P.S.... Sharp P.A. (1999)
    5. Human RNPS1 and its associated factors: a versatile alternative pre- mRNA splicing regulator in vivo. (PubMed id 14729963)1, 9 Sakashita E.... Mayeda A. (2004)
    6. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    9. A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere s hortening. (PubMed id 22379092)1 Shamay M....Hayward S.D. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9295 HGNC: 10782 AceView: SFRS11 Ensembl:ENSG00000116754 euGenes: HUgn9295
    ECgene: SRSF11 H-InvDB: SRSF11

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SRSF11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SRSF11 gene:
    Search GeneIP for patents involving SRSF11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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