SRRM5 Gene
protein-coding GIFtS: 33
GCID: GC19P044116
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serine/arginine repetitive matrix 5
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Aliases
for SRRM5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Serine/Arginine Repetitive Matrix 51 2 | | ZNF5762 3 | | Serine/Arginine Repetitive Matrix Protein 52 | | Zinc Finger Protein 5762 |
Export aliases for SRRM5 gene to outside databasesPrevious GC identifer: GC19P040547 |
Summaries
for SRRM5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SRRM5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SRRM5
Other transcription factors
Search SABiosciences Chromatin IP Primers for SRRM5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRRM5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.31 Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13.31SRRM5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P044116: view genomic region
(about GC identifiers)
Start:
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44,100,769 bp from pter |
End:
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44,118,650 bp from pter |
Size:
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17,882 bases |
Orientation:
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plus strand |
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Proteins
for SRRM5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SRRM5_HUMAN, B3KS81 (See
protein sequence)Recommended Name: Serine/arginine repetitive matrix protein 5 Size: 715 amino acids; 80355 Da
Caution: Overlaps in opposite strand with ZNF428
Sequence caution: Sequence=BAG60212.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B4DNF0Explore the universe of human proteins at neXtProt for SRRM5: NX_B3KS81
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_B3KS81
SRRM5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001139113.1
ENSEMBL proteins: ENSP00000432514 ENSP00000414512
Human Recombinant Protein Products for SRRM5:
SRRM5 Antibody Products:
Assay Products for SRRM5: |
Protein
Domains /
Families
for SRRM5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: B3KS81 |
Function
for SRRM5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM5
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM5
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SRRM5 (NM_001145641) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SRRM5 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRRM5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM5 |
|
Pathways & Interactions
for SRRM5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SRRM5
|
Drugs & Compounds
for SRRM5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SRRM5
Search CenterWatch for drugs/clinical trials and news about SRRM5
|
Transcripts
for SRRM5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SRRM5 gene: NM_001145641.1 Unigene Cluster for SRRM5: Serine/arginine repetitive matrix 5 Hs.722032 [show with all ESTs]Unigene Representative Sequence: NM_0011456412 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000526798(uc002oxb.2) ENST00000417606(uc010xwr.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM5
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM5
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SRRM5 (NM_001145641) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SRRM5 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRRM5 |
Additional cDNA sequence: AK093056.1 BC034980.1 3 DOTS entries: DT.101976913 DT.75102345 DT.91651356
GeneLoc Exon Structure
|
Expression
for SRRM5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SRRM5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCGGGGGAG
About this image
See SRRM5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SRRM5
SOURCE GeneReport for Unigene cluster: Hs.722032
SABiosciences Custom PCR Arrays for SRRM5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SRRM5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SRRM5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRRM5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRRM5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM5 |
Orthologs
for SRRM5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SRRM5 gene from 2/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
si:dkey-67c22.26CU672266.16 |
-- |
6(a)12(a) |
1 ↔ 1possible ortholog |
9(36885220-36895301) 3(1936697-1938732) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG16776 |
-- |
4(a) |
1 ↔ 1 |
X(7175122-7299793) |
Species with no ortholog for SRRM5
ENSEMBL Gene Tree for SRRM5 (if available)
TreeFam Gene Tree for SRRM5 (if available) |
Paralogs
for SRRM5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SRRM5 gene
- SRRM32 SRRM22 SRRM42 SRRM12 C2orf162
1 SIMAP similar gene for SRRM5 using alignment to 2 protein entries: SRRM5_HUMAN (see all proteins):LOC100170229
SRRM5 for paralogs About GeneDecksing
|
Genomic Variants
for SRRM5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SRRM5 |
|
Disorders
/ Diseases
for SRRM5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SRRM5 for disorders About GeneDecksing
1  disease for SRRM5: About MalaCardsmalaria
Export disorders for SRRM5 gene to outside databases
|
Publications
for SRRM5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SRRM5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SRRM5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for SRRM5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing SRRM5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SRRM5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SRRM5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SRRM5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SRRM5 gene:
Search GeneIP for patents involving SRRM5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SRRM5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SRRM5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SRRM5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SRRM5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SRRM5 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SRRM5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SRRM5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRRM5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SRRM5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRRM5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRRM5 |
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| | | | Search Tocris compounds for SRRM5 |
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 | | | SRRM5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM5 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SRRM5 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRRM5 |
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