SRRM2 Gene
protein-coding GIFtS: 50
GCID: GC16P002769
|
|
serine/arginine repetitive matrix 2
| |
Aliases
for SRRM2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Serine/Arginine Repetitive Matrix 21 2 | | 300 KDa Nuclear Matrix Antigen2 3 | | SRL3001 2 3 | | SR-Related Nuclear Matrix Protein Of 300 KDa2 3 | | KIAA03241 3 5 | | SRM3003 5 | | Cwc211 2 | | 300-KD2 | | SRm3001 2 | | CWF212 | | Ser/Arg-Related Nuclear Matrix Protein Of 300 KDa2 3 | | RNA Binding Protein2 | | Serine/Arginine-Rich Splicing Factor-Related Nuclear Matrix Protein Of 300 KDa2 3 | | Serine/Arginine Repetitive Matrix Protein 22 | | Splicing Coactivator Subunit SRm3002 3 | | TaxREB8033 | | Tax-Responsive Enhancer Element-Binding Protein 8032 3 | | TaxREB8033 |
Export aliases for SRRM2 gene to outside databasesPrevious GC identifers: GC16P002822 GC16P002802 GC16P002742 |
Summaries
for SRRM2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: SRRM2_HUMAN, Q9UQ35Function: Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at thecatalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNAsubstrate (By similarity). Binds to RNA
Gene Wiki entry for SRRM2
|
Genomic Views
for SRRM2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SRRM2 gene promoter:
AP-2alpha isoform 3 p53 Brachyury MyoD Olf-1 AP-2alpha isoform 2 PPAR-alpha Pax-4a AP-2alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for SRRM2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRRM2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3SRRM2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P002769: view genomic region
(about GC identifiers)
Start:
|
2,802,330 bp from pter |
End:
|
2,822,539 bp from pter |
Size:
|
20,210 bases |
Orientation:
|
plus strand |
|
Proteins
for SRRM2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SRRM2_HUMAN, Q9UQ35 (See
protein sequence)Recommended Name: Serine/arginine repetitive matrix protein 2 Size: 2752 amino acids; 299615 Da
Subunit: Component of the active spliceosome. Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRP70, SNRPA1,SRRM1 and SRRM2. Identified in the spliceosome C complex
Subcellular location: Nucleus speckle
Miscellaneous: Can functionally substitute for CWC12 in yeast (PubMed:19854871)
Sequence caution: Sequence=AAF21439.1; Type=Frameshift; Positions=Several; Sequence=AAF28898.1; Type=Frameshift;Positions=167, 175, 179; Sequence=AAH70050.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potentialpoly-A sequence; Sequence=BAA20782.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NKB9 D3DU97 O15038 O94803 Q6NSL3 Q6PIM3 Q6PK40 Q8IW17 Q96GY7 Q9P0G1 Q9UHA8Q9UQ36 Q9UQ37 Q9UQ38 Q9UQ40Alternative splicing: 3 isoforms: Q9UQ35-1 Q9UQ35-2 Q9UQ35-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SRRM2: NX_Q9UQ35
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UQ35
SRRM2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057417.3
ENSEMBL proteins: ENSP00000301740 ENSP00000461181 ENSP00000458870 ENSP00000459771 ENSP00000458718 ENSP00000458647 ENSP00000458230 ENSP00000460642 ENSP00000461535 ENSP00000459157
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
SRRM2 for ontologies About GeneDecksing
SRRM2 Antibody Products:
Assay Products for SRRM2: |
Protein
Domains /
Families
for SRRM2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SRRM2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UQ35ProtoNet protein and cluster: Q9UQ35 UniProtKB/Swiss-Prot: SRRM2_HUMAN, Q9UQ35Similarity: Belongs to the CWC21 family |
Function
for SRRM2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SRRM2_HUMAN, Q9UQ35Function: Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at thecatalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNAsubstrate (By similarity). Binds to RNA
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SRRM2 (NM_016333) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SRRM2 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRRM2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SRRM2 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for SRRM2:
|
Pathways & Interactions
for SRRM2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SRRM2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/655 Interacting proteins for SRRM2 (Q9UQ351, 2, 3 ENSP000003017404) via UniProtKB, MINT, STRING, and/or I2D (see all 655)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| YWHAB | P319461, 2, 3, ENSP000003001614 | EBI-1050142,EBI-359815 MINT-50974 I2D:
score=4 STRING: ENSP00000300161 | | SRRM1 | Q8IYB32, 3, ENSP000003262614 | MINT-7945693 I2D:
score=3 STRING: ENSP00000326261 | | BAK1 | Q166111, 3, ENSP000003635914 | EBI-1050142,EBI-519866 I2D:
score=2 STRING: ENSP00000363591 | | ABCF3 | Q9NUQ82, 3, ENSP000004114714 | MINT-7945693 I2D:
score=1 STRING: ENSP00000411471 | | BCAS2 | O759342, 3, ENSP000003585544 | MINT-7945693 I2D:
score=1 STRING: ENSP00000358554 |
About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000398 | mRNA splicing, via spliceosome |
IC | 11991638 |
SRRM2 for ontologies About GeneDecksing
|
Drugs & Compounds
for SRRM2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SRRM2
Search CenterWatch for drugs/clinical trials and news about SRRM2
|
Transcripts
for SRRM2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SRRM2 gene: NM_016333.3 Unigene Cluster for SRRM2: Serine/arginine repetitive matrix 2 Hs.433343 [show with all ESTs]Unigene Representative Sequence: NM_01633318/31 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 31): ENST00000301740(uc002crj.1 uc002crl.1 uc010bsu.1 uc002crk.3)
ENST00000576924 ENST00000575009 ENST00000571093 ENST00000575701 ENST00000576894
ENST00000576415 ENST00000571378 ENST00000574340 ENST00000570971 ENST00000575870
ENST00000573451 ENST00000571372 ENST00000570655 ENST00000573498 ENST00000572278
ENST00000576076 ENST00000572952
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SRRM2 (NM_016333) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SRRM2 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRRM2 |
Additional cDNA sequence: AB002322.3 AB015644.1 AB016087.1 AB016088.1 AB016089.1 AB016090.1 AB016091.1 AB016092.1 AF161338.1 AF201422.1 AK025579.1 AK025903.1 BC007752.2 BC009062.1 BC020639.1 BC028054.1 BC041155.1 BC046104.1 BC070050.1 BC107087.2 BX537511.1 BX647088.1 X97301.1 24/63 DOTS entries (see all 63): DT.95351468 DT.91798583 DT.100821089 DT.100821085 DT.450730 DT.91798478 DT.100038480 DT.100038486 DT.100821099 DT.120718913 DT.100821082 DT.99943212 DT.97771749 DT.100711397 DT.75147345 DT.120719054 DT.100821080 DT.100821098 DT.102839220 DT.120718939 DT.95165046 DT.95165070 DT.100718950 DT.120718933 24/452 AceView cDNA sequences (see all 452): BC009062 CR600414 CD244108 AI470826 BI006638 CD722216 BM509739 AW176500 CD172410 AI991472 BM505330 AL041463 BE326490 BU631060 CR623330 BQ710104 AB016091 X97301 BF992488 BM784392 BU151223 AB016090 AA347209 AB016088
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for SRRM2 (see all 18) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | · | 14d | ^ | 15a | · | 15b | · | 15c | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | |
| ExUns: | 16a | · | 16b | · | 16c | ^ | 17 | ^ | 18a | · | 18b | · | 18c | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SRRM2
|
Expression
for SRRM2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SRRM2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCTTAAAG
About this image
See SRRM2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SRRM2
SOURCE GeneReport for Unigene cluster: Hs.433343
UniProtKB/Swiss-Prot: SRRM2_HUMAN, Q9UQ35Tissue specificity: Expressed in liver, placenta, and white blood cells
SABiosciences Custom PCR Arrays for SRRM2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SRRM2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SRRM2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRRM2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRRM2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM2 |
Orthologs
for SRRM2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SRRM2 gene from 7/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
SRRM26 |
-- |
33(a) |
1 ↔ 1 |
GL343287.1(1386694-1400189) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.108562 |
Transcribed sequence with weak similarity to protein more |
72.4(n) |
|
141993450 |
zebrafish
(Danio rerio) |
Actinopterygii |
srrm26 |
serine/arginine repetitive matrix 2 |
18(a) |
possible ortholog |
3(32768346-32787254) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG79716 |
-- |
11(a) |
possible ortholog |
3L(1654247-1665064) |
worm
(Caenorhabditis elegans) |
Secernentea |
rsr-26 |
SR protein related family member (rsr-2) |
21(a) |
possible ortholog |
II(12225294-12227227) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G496016 |
uncharacterized protein |
15(a) |
1 → many |
3(18387302-18389564) |
rice
(Oryza sativa) |
Liliopsida |
-- |
expressed protein |
11(a) |
1 → many |
4(30657619-30661227) |
ENSEMBL Gene Tree for SRRM2 (if available)
TreeFam Gene Tree for SRRM2 (if available) |
Paralogs
for SRRM2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SRRM2 gene
- SRRM32 SRRM42 SRRM12 C2orf162 SRRM52
2 SIMAP similar genes for SRRM2 using alignment to 13 protein entries: SRRM2_HUMAN (see all proteins):KIAA0324 SRRM3
SRRM2 for paralogs About GeneDecksing
|
Genomic Variants
for SRRM2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SRRM2 (2802330 - 2822539 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SRRM2
2 CNVs: 4919 3988 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SRRM2 |
|
Disorders
/ Diseases
for SRRM2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SRRM2 for disorders About GeneDecksing
OMIM gene information: 606032
OMIM disorders: --
5  diseases for SRRM2: About MalaCardsacute myeloid leukemia myeloid leukemia parkinson's disease leukemia
malaria
Export disorders for SRRM2 gene to outside databases
|
Publications
for SRRM2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SRRM2 gene, integrated from 9 sources (see all 59):
(articles sorted by number of sources associating them with SRRM2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of a novel RNA-binding protein SRL300 with RS domains. (PubMed id 11004489)1, 2, 3 Sawada Y.... Ohtaki S. (2000)
- The SRm160/300 splicing coactivator subunits. (PubMed id 10668804)1, 2, 3 Blencowe B.J.... Sharp P.A. (2000)
- A coactivator of pre-mRNA splicing. (PubMed id 9531537)1, 2, 9 Blencowe B.J.... Sharp P.A. (1998)
- Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome. (PubMed id 19854871)1, 2 Grainger R.J....Beggs J.D. (2009)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
- Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
|
External Searches for SRRM2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SRRM2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SRRM2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SRRM2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SRRM2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SRRM2 gene:
Search GeneIP for patents involving SRRM2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SRRM2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SRRM2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SRRM2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SRRM2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SRRM2 | | OriGene 3'-UTR Clone for SRRM2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SRRM2 | | OriGene Custom Protein Services for SRRM2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SRRM2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SRRM2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRRM2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SRRM2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRRM2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRRM2 |
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| | | | Search Tocris compounds for SRRM2 |
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 | | | SRRM2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM2 |
|  |  |  | | | | Search ThermoFisher Antibodies for SRRM2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRRM2 |
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