Aliases for SRRM1 Gene
External Ids for SRRM1 Gene
Previous GeneCards Identifiers for SRRM1 Gene
GeneCards Summary for SRRM1 Gene
SRRM1 (Serine And Arginine Repetitive Matrix 1) is a Protein Coding gene. Among its related pathways are mRNA surveillance pathway and Formation of HIV elongation complex in the absence of HIV Tat. GO annotations related to this gene include poly(A) RNA binding.
UniProtKB/Swiss-Prot for SRRM1 Gene
Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.