SRRM1 Gene
protein-coding GIFtS: 53
GCID: GC01P024958
|
|
serine/arginine repetitive matrix 1
| |
Aliases
for SRRM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Serine/Arginine Repetitive Matrix 11 2 | | MGC394881 | | SRM1601 2 3 5 | | 160-KD2 | | POP1011 2 | | Serine/Arginine Repetitive Matrix Protein 12 | | Ser/Arg-Related Nuclear Matrix Protein2 3 | | SRm1603 | | SR-Related Nuclear Matrix Protein Of 160 KDa2 3 | | |
Export aliases for SRRM1 gene to outside databasesPrevious GC identifers: GC01P024494 GC01P024039 GC01P9A0058 GC01P9A4320 GC01P9A4714 GC01P024714 GC01P024842 GC01P023226 |
Summaries
for SRRM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: SRRM1_HUMAN, Q8IYB3Function: Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events.Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging togethersequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors ofthe spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Bindsboth pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequencespecificity and has similar preference for either double- or single-stranded nucleic acid substrates
Gene Wiki entry for SRRM1
|
Genomic Views
for SRRM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SRRM1 gene promoter:
NF-1 MEF-2 Pax-2 LUN-1 Pax-2a MEF-2A MZF-1 POU2F1 POU2F1a aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SRRM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRRM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.11 Ensembl cytogenetic band: 1p36.11 HGNC cytogenetic band: 1p36SRRM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P024958: view genomic region
(about GC identifiers)
Start:
|
24,958,207 bp from pter |
End:
|
24,999,772 bp from pter |
Size:
|
41,566 bases |
Orientation:
|
plus strand |
|
Proteins
for SRRM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SRRM1_HUMAN, Q8IYB3 (See
protein sequence)Recommended Name: Serine/arginine repetitive matrix protein 1 Size: 904 amino acids; 102335 Da
Subunit: Identified in the spliceosome C complex. Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRP70,SNRPA1, SRRM1 and SRRM2. Found in a pre-mRNA exonic splicing enhancer (ESE) complex with SNRP70, SNRPA1, SRRM1 andTRA2B/SFRS10. Found in a mRNA splicing-dependent exon junction complex (EJC) with DEK, PRPF8, NCBP1, RBM8A, RNPS1,SRRM1 and ALYREF/THOC4. Interacts with BAT1, CPSF1, RBM8A, RNPS1, and ALYREF/THOC4. Seems to be a compound of RNAexport complexes that are released from speckles in a ATP-dependent manner
Subcellular location: Nucleus matrix. Nucleus speckle
Sequence caution: Sequence=AAC09321.1; Type=Frameshift; Positions=791; Sequence=AAP97290.1; Type=Frameshift;Positions=791;
1 PDB 3D structure from  and Proteopedia  for SRRM1:1MP1 (3D)
Secondary accessions: O60585 Q5VVN4Alternative splicing: 2 isoforms: Q8IYB3-1 Q8IYB3-2 Explore the universe of human proteins at neXtProt for SRRM1: NX_Q8IYB3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IYB3
SRRM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005830.2
ENSEMBL proteins: ENSP00000326261 ENSP00000363510 ENSP00000391430 ENSP00000441776 Reactome Protein details: Q8IYB3
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
SRRM1 for ontologies About GeneDecksing
SRRM1 Antibody Products:
Assay Products for SRRM1: |
Protein
Domains /
Families
for SRRM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SRRM1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8IYB3ProtoNet protein and cluster: Q8IYB3 UniProtKB/Swiss-Prot: SRRM1_HUMAN, Q8IYB3Similarity: Belongs to the splicing factor SR familySimilarity: Contains 1 PWI domain |
Function
for SRRM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SRRM1_HUMAN, Q8IYB3Function: Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events.Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging togethersequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors ofthe spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Bindsboth pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequencespecificity and has similar preference for either double- or single-stranded nucleic acid substrates
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SRRM1 (NM_005839) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SRRM1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRRM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SRRM1 for ontologies About GeneDecksing
|
Pathways & Interactions
for SRRM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RNA Polymerase II Transcription Termination | | | 2 | mRNA Splicing - Major Pathway | | | 3 | Transcription | | | 4 | Transport of Mature Transcript to Cytoplasm | | | 5 | mRNA surveillance pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SRRM1
5/14 
Reactome Pathways for SRRM1 (see all 14)
2 
Kegg Pathways (Kegg details for SRRM1):
SRRM1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SRRM1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/843 Interacting proteins for SRRM1 (Q8IYB32, 3 ENSP000003262614) via UniProtKB, MINT, STRING, and/or I2D (see all 843)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| FUS | P356372, 3, ENSP000002541084 | MINT-7945693 MINT-7947479 I2D:
score=3 STRING: ENSP00000254108 | | BCLAF1 | Q9NYF82, 3, ENSP000000311354 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000031135 | | DDX5 | P178442, 3, ENSP000002257924 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000225792 | | DNAJA1 | P316892, 3, ENSP000003691274 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000369127 | | EEF1A1 | P681042, 3, ENSP000003300544 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000330054 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000375 | RNA splicing, via transesterification reactions |
TAS | 9531537 | | GO:0000398 | mRNA splicing, via spliceosome |
TAS | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- | | GO:0006369 | termination of RNA polymerase II transcription |
TAS | -- | | GO:0006397 | mRNA processing |
-- | -- |
SRRM1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SRRM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SRRM1
Search CenterWatch for drugs/clinical trials and news about SRRM1
|
Transcripts
for SRRM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SRRM1 gene: NM_005839.3 Unigene Cluster for SRRM1: Serine/arginine repetitive matrix 1 Hs.18192 [show with all ESTs]Unigene Representative Sequence: NM_00583918/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000471693 ENST00000478890 ENST00000323848(uc001bjm.3 uc010oel.2)
ENST00000466910 ENST00000467454 ENST00000468822 ENST00000462710 ENST00000374389
ENST00000490543 ENST00000479034(uc010oem.1 uc009vrh.1 uc009vri.1)
ENST00000494934 ENST00000495561 ENST00000485441 ENST00000470243 ENST00000496882
ENST00000461768 ENST00000485541 ENST00000488317
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SRRM1 (NM_005839) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SRRM1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRRM1 |
Additional cDNA sequence: AF048977.1 AK293576.1 AK302498.1 AK307419.1 AK307568.1 BC011019.1 BC017315.2 BC036187.1 BC107072.1 24/27 DOTS entries (see all 27): DT.452746 DT.100642918 DT.121446234 DT.97862160 DT.121470206 DT.318378 DT.121446215 DT.121446241 DT.318382 DT.121446187 DT.100825661 DT.70100635 DT.70101684 DT.95352276 DT.121317776 DT.100825652 DT.100825659 DT.318386 DT.92027950 DT.121446186 DT.95228282 DT.95352272 DT.100825653 DT.121446209 24/444 AceView cDNA sequences (see all 444): BM477996 BM016512 AA309994 CA446556 BU784788 AA828260 BM678067 BF056299 CF147475 AI636897 CA454259 BF915139 BX483801 NM_005839 AI239638 BC017315 BM557505 BQ083156 H29314 AI003232 BQ716385 AJ572762 BM785940 CB154179
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for SRRM1 (see all 12) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17 | ^ |
|---|
|
| SP1: | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18a | · | 18b | ^ | 19 | ^ | 20 |
|---|
|
| SP1: | | | | | | | | | |
| SP2: | | | | | | | | | |
| SP3: | | | | | | | | | |
| SP4: | | | | | | | | | |
| SP5: | | | | | | | | |
ECgene alternative splicing isoforms for SRRM1
|
Expression
for SRRM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SRRM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTCTGTTCA
About this image
See SRRM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SRRM1
SOURCE GeneReport for Unigene cluster: Hs.18192
SABiosciences Custom PCR Arrays for SRRM1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SRRM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SRRM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRRM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRRM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM1 |
Orthologs
for SRRM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SRRM1 gene from 8/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SRRM11 |
serine/arginine repetitive matrix 1 |
79.52(n)
89.82(a) |
|
428216 NM_001031494.1 NP_001026665.1 |
lizard
(Anolis carolinensis) |
Reptilia |
SRRM16 |
-- |
81(a) |
1 ↔ 1 |
GL343464.1(145309-161862) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BC043777.12 |
-- |
75.44(n) |
|
BC043777.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
BC058068.12 |
-- |
74.26(n) |
|
BC058068.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG112743
SRm1601 |
CG11274-PA1 |
64(a)3
39.78(n)1
34.41(a)1 |
|
69F63
394831 NM_140370.21 NP_648627.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
rsr-11 , 3 |
Protein RSR-11 |
43(a)3
43.09(n)1
40.77(a)1 |
|
I(11186121-11190118)3
1730131 NM_060474.41 NP_492875.21 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G292101 |
serine/arginine repetitive matrix protein 1 |
45(n)
38.06(a) |
|
817470 NM_128477.3 NP_180484.2 |
rice
(Oryza sativa) |
Liliopsida |
-- |
retrotransposon protein, putative, unclassified, e... |
20(a) |
1 ↔ 1 |
3(9027709-9034275) |
ENSEMBL Gene Tree for SRRM1 (if available)
TreeFam Gene Tree for SRRM1 (if available) |
Paralogs
for SRRM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SRRM1 gene
- SRRM32 SRRM22 SRRM42 C2orf162 SRRM52
SRRM1 for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for SRRM1
PGOHUM00000240661 PGOHUM00000238089 PGOHUM00000249505 PGOHUM00000241573
|
Genomic Variants
for SRRM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SRRM1 (24958207 - 24999772 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SRRM1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SRRM1 |
|
Disorders
/ Diseases
for SRRM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SRRM1 for disorders About GeneDecksing
OMIM gene information: 605975
OMIM disorders: --
5  diseases for SRRM1: About MalaCardsbullous pemphigoid acute myeloid leukemia myeloid leukemia leukemia
malaria
1 disease from the University of Copenhagen DISEASES database for SRRM1:Bullous pemphigoid Export disorders for SRRM1 gene to outside databases
|
Publications
for SRRM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SRRM1 gene, integrated from 9 sources (see all 66):
(articles sorted by number of sources associating them with SRRM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A coactivator of pre-mRNA splicing. (PubMed id 9531537)1, 2, 3, 9 Blencowe B.J.... Sharp P.A. (1998)
- The spatial targeting and nuclear matrix binding domains of SRm160. (PubMed id 12624182)1, 2, 9 Wagner S.... Nickerson J.A. (2003)
- The SRm160/300 splicing coactivator is required for exon-enhancer function. (PubMed id 10339552)1, 2, 9 Eldridge A.G.... Blencowe B.J. (1999)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
- In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160. (PubMed id 15024032)1, 2 Wagner S.... Nickerson J.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation. (PubMed id 12944400)1, 2 McCracken S.... Blencowe B.J. (2003)
|
External Searches for SRRM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SRRM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing SRRM1 gene
(According to HUGE)
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Specialized Databases showing SRRM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for SRRM1 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for SRRM1 gene:
Search GeneIP for patents involving SRRM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SRRM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SRRM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SRRM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SRRM1 | | | OriGene Protein Over-expression Lysate for SRRM1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SRRM1 | | OriGene 3'-UTR Clone for SRRM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRRM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SRRM1 | | OriGene Custom Protein Services for SRRM1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SRRM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SRRM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRRM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SRRM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRRM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRRM1 |
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| | | | Search Tocris compounds for SRRM1 |
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 | | | SRRM1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRRM1 |
|  |  |  | | | | Search ThermoFisher Antibodies for SRRM1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRRM1 |
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