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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SRPR Gene

protein-coding   GIFtS: 60
GCID: GC11M126132

Signal Recognition Particle Receptor (Docking Protein)

(Previous name: signal recognition particle receptor ('docking protein'))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Signal Recognition Particle Receptor (Docking Protein)1 2     DP2
Docking Protein Alpha2 3     SRP-alpha2
DP-alpha2 3     Sralpha2
SR-alpha2 3     Signal Recognition Particle Receptor Subunit Alpha2
Signal Recognition Particle Receptor ('Docking Protein')1     

External Ids:    HGNC: 113071   Entrez Gene: 67342   Ensembl: ENSG000001829347   OMIM: 1821805   UniProtKB: P082403   

Export aliases for SRPR gene to outside databases

Previous GC identifers: GC11U990126 GC11M127645 GC11M126166 GC11M125670 GC11M125638 GC11M122075


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SRPR Gene:
The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction
with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged
secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple
transcript variants. (provided by RefSeq, Apr 2010)

GeneCards Summary for SRPR Gene: 
SRPR (signal recognition particle receptor (docking protein)) is a protein-coding gene. Diseases associated with SRPR include conjunctivitis, and diphtheria, and among its related super-pathways are Activation of Chaperones by IRE1alpha and Viral mRNA Translation. GO annotations related to this gene include signal recognition particle binding and GTP binding.

UniProtKB/Swiss-Prot: SRPR_HUMAN, P08240
Function: Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal
recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum
membrane system




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SRPR gene promoter:
         HFH-3   HOXA3   Brachyury   HSF1 (long)   NRSF form 2   c-Ets-1   FOXI1   IRF-7A   HSF1short   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSRPR promoter sequence
   Search SABiosciences Chromatin IP Primers for SRPR

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRPR


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24.2   Ensembl cytogenetic band:  11q24.2   HGNC cytogenetic band: 11q24-q25

SRPR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRPR gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M126132:  view genomic region     (about GC identifiers)

Start:
126,132,814 bp from pter      End:
126,139,039 bp from pter
Size:
6,226 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SRPR_HUMAN, P08240 (See protein sequence)
Recommended Name: Signal recognition particle receptor subunit alpha  
Size: 638 amino acids; 69811 Da
Subunit: Heterodimer with SRPRB
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Thought to be anchored in
the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain
2 PDB 3D structures from and Proteopedia for SRPR:
2FH5 (3D)        2GO5 (3D)    
Secondary accessions: A6NIB3 B2R5Z8 B4E0H3 E9PJS4 Q9BVJ4
Alternative splicing: 2 isoforms:  P08240-1   P08240-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SRPR: NX_P08240

Explore proteomics data for SRPR at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P08240

  • SRPR Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SRPR Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001171313.1  NP_003130.2  

    ENSEMBL proteins: 
     ENSP00000328023   ENSP00000435508  
    Reactome Protein details: P08240
    Human Recombinant Protein Products for SRPR: 
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    Cloud-Clone Corp. Proteins for SRPR 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum TAS2827661
    GO:0005785signal recognition particle receptor complex IEA--
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0016020membrane IDA--
    GO:0016021integral to membrane TAS2827661

    SRPR for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR007222 Sig_recog_particle_rcpt_asu_N
     IPR013822 Signal_recog_particl_SRP54_hlx
     IPR027417 P-loop_NTPase
     IPR003593 AAA+_ATPase
     IPR000897 SRP54_GTPase_dom

    Graphical View of Domain Structure for InterPro Entry P08240

    ProtoNet protein and cluster: P08240

    1 Blocks protein domain: IPB000897 GTP-binding signal recognition particle (SRP54) G-domain

    UniProtKB/Swiss-Prot: SRPR_HUMAN, P08240
    Similarity: Belongs to the GTP-binding SRP family


    SRPR for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SRPR_HUMAN, P08240
    Function: Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal
    recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum
    membrane system

         Genatlas biochemistry entry for SRPR:
    signal recognition particle receptor,'docking protein'

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003924GTPase activity IEA--
    GO:0005047signal recognition particle binding IEA--
    GO:0005525GTP binding IEA--
    GO:0017111nucleoside-triphosphatase activity ----
         
    SRPR for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SRPR 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SRPR 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SRPR 

    miRNA
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    miRTarBase miRNAs that target SRPR:
    hsa-mir-16 (MIRT001409)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SRPR
    8/36 QIAGEN miScript miRNA Assays for microRNAs that regulate SRPR (see all 36):
    hsa-miR-330-5p hsa-miR-15a hsa-miR-25 hsa-miR-503 hsa-miR-759 hsa-miR-449a hsa-miR-1184 hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidSRPR 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRPR


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SRPR About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Activation of Chaperone Genes by XBP1(S)
    Activation of Chaperones by IRE1alpha0.94
    Unfolded Protein Response0.76
    Activation of Chaperone Genes by XBP1(S)0.94
    2Viral mRNA Translation
    Translation0.78
    SRP-dependent cotranslational protein targeting to membrane0.77
    3Generic Transcription Pathway
    Gene Expression0.47
    4Asparagine N-linked glycosylation
    Metabolism of proteins0.35
    5Protein export
    Protein export

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5/7        Reactome Pathways for SRPR (see all 7)
        Activation of Chaperone Genes by XBP1(S)
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Metabolism of proteins
    Activation of Chaperones by IRE1alpha


    1         Kegg Pathway  (Kegg details for SRPR):
        Protein export


    SRPR for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SRPR

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/131 Interacting proteins for SRPR (P082402, 3 ENSP000003280234) via UniProtKB, MINT, STRING, and/or I2D (see all 131)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206353Q154773I2D: score=1 
    ENSG00000223493Q154773I2D: score=1 
    ENSG00000225737Q154773I2D: score=1 
    ENSG00000228896Q154773I2D: score=1 
    ENSG00000232616Q154773I2D: score=1 
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006412translation TAS--
    GO:0006613cotranslational protein targeting to membrane TAS2827661
    GO:0006614SRP-dependent cotranslational protein targeting to membrane TAS--
    GO:0006810transport ----

    SRPR for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SRPR for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SRPR

    1 HMDB Compound for SRPR    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    1 Novoseek inferred chemical compound relationship for SRPR gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gtp 67.9 15 1315314 (3), 7803856 (3), 9182758 (2), 11566135 (1)

    Search CenterWatch for drugs/clinical trials and news about SRPR

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SRPR gene (2 alternative transcripts): 
    NM_001177842.1  NM_003139.3  

    Unigene Cluster for SRPR:

    Signal recognition particle receptor (docking protein)
    Hs.368376  [show with all ESTs]
    Unigene Representative Sequence: NM_003139
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000332118(uc001qdh.3 uc010sbm.2) ENST00000532259 ENST00000532268
    ENST00000531104 ENST00000527817 ENST00000528744 ENST00000530680
    miRNA
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    8/36 QIAGEN miScript miRNA Assays for microRNAs that regulate SRPR (see all 36):
    hsa-miR-330-5p hsa-miR-15a hsa-miR-25 hsa-miR-503 hsa-miR-759 hsa-miR-449a hsa-miR-1184 hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidSRPR 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRPR
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    Additional mRNA sequence: 

    AK130382.1 AK303379.1 AK312377.1 BC001162.1 BC008077.2 BC009110.1 BC013583.1 CR457025.1 
    X06272.1 

    19 DOTS entries:

    DT.100885980  DT.100798722  DT.448082  DT.95209126  DT.97855045  DT.95331436  DT.95075047  DT.120713201 
    DT.119813  DT.100885981  DT.95347978  DT.101962648  DT.92451741  DT.95376234  DT.95376240  DT.100030608 
    DT.100885979  DT.92451732  DT.100878456 

    24/638 AceView cDNA sequences (see all 638):

    BQ447273 N26578 BQ024111 BU178217 BU735771 BQ430052 CB164391 BU789492 
    AI951469 AL713396 BU630251 BF791781 CN481121 CA423550 BM550749 CA427001 
    BM781895 BQ775058 BE466471 BE220212 AI498162 BQ682996 BM967241 CA488101 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SRPR expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCCCCTTCC
    SRPR Expression
    About this image


    See SRPR Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SRPR

    SOURCE GeneReport for Unigene cluster: Hs.368376
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SRPR gene from 10/27 species (see all 27)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Srpr1 , 5 signal recognition particle receptor ('docking protein')1, 5 91.72(n)1
    97.48(a)1
      9 (20.06 cM)5
    673981  NM_026130.11  NP_080406.11 
     352001755 
    chicken
    (Gallus gallus)
    Aves SRPR1 signal recognition particle receptor (docking protein) 74.87(n)
    80.13(a)
      419713  NM_001039277.1  NP_001034366.1 
    lizard
    (Anolis carolinensis)
    Reptilia SRPR6
    Uncharacterized protein
    77(a)
    1 ↔ 1
    GL343322.1(1079321-1096052)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.119282 Transcribed sequence with moderate similarity to protein more 78.82(n)    137715251 
    zebrafish
    (Danio rerio)
    Actinopterygii idibd10642 idibd1064 76.8(n)   338111  57058352 
    fruit fly
    (Drosophila melanogaster)
    Insecta Gtp-bp1 GTP-binding protein 58.98(n)
    55.22(a)
      47251  NM_080148.2  NP_524887.2 
    worm
    (Caenorhabditis elegans)
    Secernentea W09G12.53
    CELE_F38A1.81
    GTP-binding protein3
    Protein F38A1.81
    80(a)
    (best of 2)3
    55(n)1
    53.57(a)1
      IV(1233538-1234740)3
    1854381  NM_171254.31  NP_741303.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SRP101(YDR292C)4
    SRP1011
    Signal recognition particle (SRP) receptor alpha subunit; more4
    Srp101p1
    47.19(n)1
    43.23(a)1
      4(1045011-1043146)4
    8518861, 4  NP_010578.31  NP_010578.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G306001 signal recognition particle receptor subunit alpha 53.11(n)
    46.72(a)
      829183  NM_119206.4  NP_194789.1 
    rice
    (Oryza sativa)
    Liliopsida Os.48382 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 74.32(n)    AK101591.1 


    ENSEMBL Gene Tree for SRPR (if available)
    TreeFam Gene Tree for SRPR (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/167 SNPs in SRPR are shown (see all 167)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1389844651,2
    --126133401(+) CAAGAA/CCTGGC 2 -- ut310--------
    rs1416010671,2
    C--126133413(+) CTGGCC/TCTGGA 2 -- ut310--------
    rs1918780841,2
    --126133423(+) AAGAGG/TCTCTT 2 -- ut310--------
    rs116022941,2
    C,F,H--126133561(+) AAGGGG/AGTGCC 2 -- ut315Minor allele frequency- A:0.01NS EA NA 382
    rs10496661,2
    C,F,A,H--126133576(-) CCCCCT/CTCCTA 2 -- ut31 trp318Minor allele frequency- C:0.13NS EA NA CSA WA 2342
    rs31898501,2
    C,F,A,H--126133587(-) CCAGCG/TGGCCT 2 -- ut3118Minor allele frequency- T:0.15MN NS EA NA CSA WA 2506
    rs559444211,2
    C--126133588(+) GGCCCG/ACTGGG 2 -- ut312Minor allele frequency- A:0.06WA 120
    rs10496651,2
    C,F,A,H--126133632(-) AAGGAA/GGGCCT 2 -- ut3125Minor allele frequency- G:0.14EA MN NS NA CSA WA 4174
    rs5293281,2
    C,F,A,H--126133641(-) GCCATC/TTGCAA 2 -- ut3123Minor allele frequency- T:0.14MN NS EA NA WA 2612
    rs22423901,2
    C,F,H--126133670(+) GTGGGA/C/GTTGGA 4 -- ut317EA NA CSA 1359

    HapMap Linkage Disequilibrium report for SRPR (126132814 - 126139039 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SRPR: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SRPR
    DNA2.0 Custom Variant and Variant Library Synthesis for SRPR

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 182180    OMIM disorders: --

    3 diseases for SRPR:    About MalaCards
    conjunctivitis    diphtheria    tuberculosis

    1 disease from the University of Copenhagen DISEASES database for SRPR:
    Diphtheria

    SRPR for disorders           About GeneDecksing


    Export disorders for SRPR gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SRPR gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with SRPR)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete cDNA sequence coding for human docking protein. (PubMed id 3340536)1, 2, 3 Hortsch M.... Meyer D.I. (1988)
    2. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. PCR-assisted localization of the human SRPR gene. (PubMed id 1312991)1, 3 Janin N....Lipinski M. (1992)
    5. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    6. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    7. SGTA recognizes a noncanonical ubiquitin-like domain i n the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degra dation. (PubMed id 23246001)1 Xu Y....Ye Y. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6734 HGNC: 11307 AceView: SRPR Ensembl:ENSG00000182934 euGenes: HUgn6734
    ECgene: SRPR Kegg: 6734 H-InvDB: SRPR

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SRPR Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SRPR Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SRPR gene:
    Search GeneIP for patents involving SRPR

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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