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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SRP9 Gene

protein-coding   GIFtS: 54
GCID: GC01P225965

Signal Recognition Particle 9kDa

(Previous name: signal recognition particle 9kD)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Signal Recognition Particle 9kDa1 2
Signal Recognition Particle 9kD1
ALURBP2
Signal Recognition Particle 9 KDa Protein2

External Ids:    HGNC: 113041   Entrez Gene: 67262   Ensembl: ENSG000001437427   OMIM: 6007075   UniProtKB: P494583   

Export aliases for SRP9 gene to outside databases

Previous GC identifers: GC01P224447 GC01P221782 GC01P222372 GC01P222940 GC01P222272 GC01P224034 GC01P196483


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SRP9 Gene: 
SRP9 (signal recognition particle 9kDa) is a protein-coding gene. Diseases associated with SRP9 include sost-related sclerosing bone dysplasia, and colorectal cancer, and among its related super-pathways are Viral mRNA Translation and Generic Transcription Pathway. GO annotations related to this gene include RNA binding and signal recognition particle binding.

UniProtKB/Swiss-Prot: SRP09_HUMAN, P49458
Function: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough
endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the
elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SRP9 gene promoter:
         Spz1   STAT1   NF-1   AML1a   STAT1beta   LCR-F1   STAT1alpha   AREB6   STAT3   Chx10   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSRP9 promoter sequence
   Search SABiosciences Chromatin IP Primers for SRP9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRP9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.12   Ensembl cytogenetic band:  1q42.12   HGNC cytogenetic band: 1q42.12

SRP9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRP9 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P225965:  view genomic region     (about GC identifiers)

Start:
225,965,515 bp from pter      End:
225,978,168 bp from pter
Size:
12,654 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SRP09_HUMAN, P49458 (See protein sequence)
Recommended Name: Signal recognition particle 9 kDa protein  
Size: 86 amino acids; 10112 Da
Subunit: Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits:
SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9
Subcellular location: Cytoplasm
3 PDB 3D structures from and Proteopedia for SRP9:
1E8O (3D)        1E8S (3D)        1RY1 (3D)    
Secondary accessions: A8K0N0 Q6NVX0 Q8WTW0
Alternative splicing: 2 isoforms:  P49458-1   P49458-2   (Ref.5 (AAH21995) sequence is in conflict in position: 64:I->M)

Explore the universe of human proteins at neXtProt for SRP9: NX_P49458

Explore proteomics data for SRP9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P49458

  • SRP9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SRP9 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001123912.1  NP_003124.1  

    ENSEMBL proteins: 
     ENSP00000305230   ENSP00000355804   ENSP00000355803  
    Reactome Protein details: P49458
    Human Recombinant Protein Products for SRP9: 
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    Novus Biologicals SRP9 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SRP9 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005785signal recognition particle receptor complex TAS7730321
    GO:0005786signal recognition particle, endoplasmic reticulum targeting NAS17154533
    GO:0005829cytosol TAS--
    GO:0048500signal recognition particle ----

    SRP9 for ontologies           About GeneDecksing



    SRP9 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR008832 Signal_recog_particle_SRP9
     IPR009018 Signal_recog_particle_SRP9/14

    Graphical View of Domain Structure for InterPro Entry P49458

    ProtoNet protein and cluster: P49458

    1 Blocks protein domain: IPB008832 Signal recognition particle 9 kDa

    UniProtKB/Swiss-Prot: SRP09_HUMAN, P49458
    Similarity: Belongs to the SRP9 family


    SRP9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SRP09_HUMAN, P49458
    Function: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough
    endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the
    elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS7730321
    GO:0005047signal recognition particle binding TAS7730321
    GO:00083127S RNA binding IEA--
         
    SRP9 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SRP9 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SRP9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SRP9 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SRP9 

    miRNA
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    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate SRP9 (see all 9):
    hsa-miR-607 hsa-miR-1237 hsa-miR-4251 hsa-miR-578 hsa-miR-146a* hsa-miR-494 hsa-miR-129-3p hsa-miR-3145-3p
    SwitchGear 3'UTR luciferase reporter plasmidSRP9 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SRP9 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Viral mRNA Translation
    Translation0.78
    SRP-dependent cotranslational protein targeting to membrane0.77
    2Generic Transcription Pathway
    Gene Expression0.47
    3Asparagine N-linked glycosylation
    Metabolism of proteins0.35
    4Protein export
    Protein export

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for SRP9
        Translation
    SRP-dependent cotranslational protein targeting to membrane
    Metabolism of proteins
    Gene Expression


    1         Kegg Pathway  (Kegg details for SRP9):
        Protein export


    SRP9 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SRP9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/27 Interacting proteins for SRP9 (P494582, 3 ENSP000003052304) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LIN54Q6MZP73, ENSP000003419474I2D: score=1 STRING: ENSP00000341947
    MAP1LC3AQ9H4923, ENSP000003639704I2D: score=1 STRING: ENSP00000363970
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    SRP14P371083, ENSP000002678844I2D: score=3 STRING: ENSP00000267884
    EPB41P111713, ENSP000002901004I2D: score=1 STRING: ENSP00000290100
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation TAS--
    GO:0006614SRP-dependent cotranslational protein targeting to membrane TAS--
    GO:0010467gene expression TAS--
    GO:0044267cellular protein metabolic process TAS--
    GO:0045900negative regulation of translational elongation IEA--

    SRP9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SRP9 (SRP09)

    Search CenterWatch for drugs/clinical trials and news about SRP9 / SRP09

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SRP9 gene (2 alternative transcripts): 
    NM_001130440.1  NM_003133.5  

    Unigene Clusters for SRP9:

    Signal recognition particle 9kDa
    Hs.511425  [show with all ESTs], Hs.706900  [show with all ESTs]
    Unigene Representative Sequences: BC064351, BF693963
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000304786(uc001hpf.4 uc001hpg.3 uc001hpi.4) ENST00000366839(uc001hph.3)
    ENST00000366838

    miRNA
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    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate SRP9 (see all 9):
    hsa-miR-607 hsa-miR-1237 hsa-miR-4251 hsa-miR-578 hsa-miR-146a* hsa-miR-494 hsa-miR-129-3p hsa-miR-3145-3p
    SwitchGear 3'UTR luciferase reporter plasmidSRP9 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SRP9
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): SRP9 (NM_001130440)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SRP9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRP9
    Sirion Biotech Customized lentivirus for stable overexpression of SRP9 
                         Customized lentivirus expression plasmids for stable overexpression of SRP9 
    Primer
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    OriGene qPCR primer pairs and template standards for SRP9
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRP9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRP9

    Additional mRNA sequence: 

    BC021995.1 BC067845.1 DQ786272.1 EF488978.1 

    24/63 DOTS entries (see all 63):

    DT.100809332  DT.92472791  DT.92472828  DT.449332  DT.100888897  DT.100888900  DT.100045223  DT.92472821 
    DT.100033394  DT.100888882  DT.95242459  DT.100888845  DT.92472835  DT.100888881  DT.100888844  DT.100888888 
    DT.100888849  DT.100888865  DT.101971899  DT.121247945  DT.100888858  DT.121247944  DT.100648946  DT.100045228 

    24/2079 AceView cDNA sequences (see all 2079):

    AA665622 BM478487 AA425366 AA679839 AA037856 CB160647 T40979 AI889123 
    BU170472 BU786101 AA542954 BG613240 AA358376 CB215550 CR618157 AW070673 
    BG530810 AA553371 CR610100 BU786173 AW516210 BG501457 BP338632 N42128 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SRP9    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c
    SP1:                          -                     
    SP2:                    -     -     -               
    SP3:                    -                           


    ECgene alternative splicing isoforms for SRP9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SRP9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTCAGAGAG
    SRP9 Expression
    About this image


    See SRP9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SRP9

    SOURCE GeneReport for Unigene clusters: Hs.511425 Hs.706900
        SABiosciences Custom PCR Arrays for SRP9
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRP9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SRP9 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Srp91 , 5 signal recognition particle 91, 5 88.37(n)1
    93.02(a)1
      1 (84.93 cM)5
    270581  NM_012058.31  NP_036188.11 
     1821247375 
    chicken
    (Gallus gallus)
    Aves SRP91 signal recognition particle 9kDa 83.72(n)
    82.56(a)
      770243  NM_001097536.1  NP_001091005.1 
    lizard
    (Anolis carolinensis)
    Reptilia SRP96
    Signal recognition particle 9 kDa protein
    84(a)
    1 ↔ 1
    1(251749426-251754861)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.52262 Xenopus laevis transcribed sequence with moderate similarity more 80.42(n)    BJ613515.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc566682 similar to signal recognition particle 9kDa 73.13(n)   394071  BC049522.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Srp96
    Signal recognition particle protein 9
    40(a)
    1 ↔ 1
    3L(7929473-7930358)
    worm
    (Caenorhabditis elegans)
    Secernentea ZK512.46
    Signal recognition particle 9 kDa protein
    51(a)
    1 ↔ 1
    III(9145325-9145976)


    ENSEMBL Gene Tree for SRP9 (if available)
    TreeFam Gene Tree for SRP9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SRP9 gene
    1 SIMAP similar gene for SRP9 using alignment to 3 protein entries:     SRP09_HUMAN (see all proteins):
    DKFZp564M2223

    SRP9 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/353 SNPs in SRP9 are shown (see all 353)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1824392301,2
    --225963522(+) GCCCTC/GTCTGC 2 -- us2k10--------
    rs1114529761,2
    C--225963559(+) CCTCAACAC/-  
            
    ACACA
    2 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs46536721,2
    A--225963578(+) acacaC/Gacaca 2 -- us2k10--------
    rs1998931121,2
    --225963578(+) CACAC-/AGACACA 2 -- us2k10--------
    rs38202271,2
    C,F--225963580(+) ACACAG/CACACA 2 -- us2k13Minor allele frequency- C:0.50WA NA CSA 6
    rs1469186941,2
    C--225963580(+) cacac-/AGacaca 2 -- us2k10--------
    rs339445131,2
    C--225963581(+) ACACA-/AGCACAC 2 -- us2k10--------
    rs38202281,2
    C--225963591(+) CACACG/ATGTCT 2 -- us2k11Minor allele frequency- A:0.00NA 2
    rs1396402551,2
    C--225963591(+) CACAC-/GTGTCTC 2 -- us2k10--------
    rs38202291,2
    C--225963592(+) ACACGT/CGTCTC 2 -- us2k11Minor allele frequency- C:0.00NA 2

    HapMap Linkage Disequilibrium report for SRP9 (225965515 - 225978168 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SRP9:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv832736CNV Loss17160897
    nsv524126CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SRP9
    DNA2.0 Custom Variant and Variant Library Synthesis for SRP9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600707    OMIM disorders: --

    2 diseases for SRP9:    About MalaCards
    sost-related sclerosing bone dysplasia    colorectal cancer

    1 disease from the University of Copenhagen DISEASES database for SRP9:
    SOST-related sclerosing bone dysplasia

    SRP9 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for SRP9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SRP9 gene, integrated from 9 sources (see all 51):
    (articles sorted by number of sources associating them with SRP9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human signal recognition particle (SRP) Alu-associated protein also binds Alu interspersed repeat sequence RNAs. Characterization of human SRP9. (PubMed id 7730321)1, 2, 3 Hsu K.... Maraia R.J. (1995)
    2. Structure and assembly of the Alu domain of the mammalian signal recognition particle. (PubMed id 11089964)1, 2, 9 Weichenrieder O....Cusack S. (2000)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Proteomic expression analysis of surgical human colorectal cancer tissues: up-regulation of PSB7, PRDX1, and SRP9 and hypoxic adaptation in cancer. (PubMed id 18549262)1, 9 Rho J.H.... Roehrl M.H. (2008)
    5. Assembly of the Alu domain of the signal recognition particle (SRP): dimerization of the two protein components is required for efficient binding to SRP RNA. (PubMed id 2153922)1, 9 Strub K. and Walter P. (1990)
    6. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    7. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PubMed id 23349634)1 Cloutier P.... Coulombe B. (2013)
    8. Cleavage and polyadenylation specificity factor 1 (CPS F1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6. (PubMed id 23151878)1 Evsyukova I....Garcia-Blanco M.A. (2013)
    9. Implication of the SMN complex in the biogenesis and s teady state level of the signal recognition particle. (PubMed id 23221635)1 Piazzon N....Massenet S. (2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6726 HGNC: 11304 AceView: SRP9 Ensembl:ENSG00000143742 euGenes: HUgn6726
    ECgene: SRP9 Kegg: 6726 H-InvDB: SRP9

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SRP9 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Signal-recognition_particle

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SRP9 gene:
    Search GeneIP for patents involving SRP9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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