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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SRP72 Gene

protein-coding   GIFtS: 57
GCID: GC04P057334

signal recognition particle 72kDa

(Previous name: signal recognition particle 72kD )
 Explore 6 diseases affiliated with
SRP72 via our new
 Human Malady Compendium 
Biological research products
for SRP72
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Signal Recognition Particle 72kDa1 2
Signal Recognition Particle 72kD1
BMFF2
Signal Recognition Particle 72 KDa Protein2

External Ids:    HGNC: 113031   Entrez Gene: 67312   Ensembl: ENSG000001747807   OMIM: 6021225   UniProtKB: O760943   

Export aliases for SRP72 gene to outside databases

Previous GC identifers: GC04P057137 GC04P057295 GC04P057249 GC04P057174 GC04P057028 GC04P053287


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SRP72:
This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that
mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA
and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or
heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal
recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in
this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Jun 2012)

UniProtKB/Swiss-Prot: SRP72_HUMAN, O76094
Function: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough
endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might
interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest
function




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_022853.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SRP72 gene promoter:
         AML1a   GATA-3   ATF-2   GATA-2   GATA-1   POU2F1a   Sox9   FOXO1a   FOXO1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSRP72 promoter sequence
   Search SABiosciences Chromatin IP Primers for SRP72

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRP72


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q11   Ensembl cytogenetic band:  4q12   HGNC cytogenetic band: 4q11

SRP72 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRP72 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P057334:  view genomic region     (about GC identifiers)

Start:
57,333,081 bp from pter      End:
57,369,847 bp from pter
Size:
36,767 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SRP72_HUMAN, O76094 (See protein sequence)
Recommended Name: Signal recognition particle 72 kDa protein  
Size: 671 amino acids; 74606 Da
Subunit: Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72,
SRP68, SRP54, SRP19, SRP14 and SRP9
Subcellular location: Cytoplasm. Endoplasmic reticulum
Sequence caution: Sequence=CAD97950.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=CAD97950.1; Type=Frameshift; Positions=565;
Secondary accessions: G5E9Z8 Q7Z3C0
Alternative splicing: 2 isoforms:  O76094-1   O76094-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SRP72: NX_O76094

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O76094

  • SRP72 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001254651.1  NP_008878.3  

    ENSEMBL proteins: 
     ENSP00000342181   ENSP00000424576   ENSP00000425190  
    Reactome Protein details: O76094
    Human Recombinant Protein Products: 
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    Uscn Proteins for SRP72

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005783endoplasmic reticulum IDA--
    GO:0005786signal recognition particle, endoplasmic reticulum targeting IDA18089836
    GO:0005829cytosol TAS--


    SRP72 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SRP72 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR001440 TPR-1
     IPR011990 TPR-like_helical
     IPR013699 Signal_recog_part_SRP72_RNA-bd
     IPR026270 SRP72
     IPR013026 TPR-contain_dom

    Graphical View of Domain Structure for InterPro Entry O76094

    ProtoNet protein and cluster: O76094

    1 Blocks protein family: IPB013699 SRP72 RNA-binding

    UniProtKB/Swiss-Prot: SRP72_HUMAN, O76094
    Domain: The C-terminus is essential for the interaction with the SRP68/7S RNA complex (By similarity)
    Similarity: Belongs to the SRP72 family
    Similarity: Contains 5 TPR repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: SRP72_HUMAN, O76094
    Function: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough
    endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might
    interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest
    function

         Genatlas biochemistry entry for SRP72:
    signal recognition particle,72kDa,inconsistant localisation,except if the gene on chromosome 18 is a novel gene
    resulting from transplicing from CAMK2G on chromosome 10 and SRP72 on chroumosome 1

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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005047signal recognition particle binding IPI17254600
    GO:00083127S RNA binding IEA--


    SRP72 for ontologies           About GeneDecksing


    4 GenomeRNAi human phenotypes for SRP72:
     Decreased G3BP1 protein expres  Decreased nuclei size in G2M  Increased viability with TRAIL  Synthetic lethal with Ras 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    SRP-dependent cotranslational protein targeting to membrane0.77
    Translation0.57
    2Protein export
    Protein export1.00
    3Generic Transcription Pathway
    Gene Expression0.46
    4Asparagine N-linked glycosylation
    Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for SRP72
        Translation
    SRP-dependent cotranslational protein targeting to membrane
    Metabolism of proteins
    Gene Expression


    1         Kegg Pathway  (Kegg details for SRP72):
        Protein export


    SRP72 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SRP72

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/831 Interacting proteins for SRP72 (O760942, 3 ENSP000003421814) via UniProtKB, MINT, STRING, and/or I2D (see all 831)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SRP68Q9UHB92, 3, ENSP000003120664MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000312066
    SKILP127572, 3MINT-61670 I2D: score=3 
    RPL22P352682, ENSP000003460884MINT-7945693 MINT-7947479 STRING: ENSP00000346088
    SRP54P610112, ENSP000002167744MINT-7945693 MINT-7947479 STRING: ENSP00000216774
    HNRNPA1P096512, 3, ENSP000003418264MINT-7945693 I2D: score=1 STRING: ENSP00000341826
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation TAS--
    GO:0006614SRP-dependent cotranslational protein targeting to membrane TAS--
    GO:0010467gene expression TAS--
    GO:0042493response to drug IDA18089836
    GO:0044267cellular protein metabolic process TAS--


    SRP72 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SRP72
    Search CenterWatch for drugs/clinical trials and news about SRP72 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SRP72 gene (2 alternative transcripts): 
    NM_001267722.1  NM_006947.3  

    Unigene Cluster for SRP72:

    Signal recognition particle 72kDa
    Hs.237825  [show with all ESTs]
    Unigene Representative Sequence: NM_006947
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000342756(uc003hbv.3 uc010ihe.3) ENST00000510663 ENST00000504757
    ENST00000505314 ENST00000507126(uc003hbx.3)

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    Additional cDNA sequence: 

    AF038851.1 AF069765.1 AF077019.1 AF086131.1 AF086530.1 AK023480.1 AK225430.1 AK307397.1 
    BC017057.1 BC032609.1 BC040134.1 BC046143.1 BC056901.1 BC065018.1 BC105583.1 BX537991.1 

    24/26 DOTS entries (see all 26):

    DT.97805941  DT.115778  DT.100885672  DT.100885677  DT.100885669  DT.100885674  DT.91758328  DT.91758329 
    DT.121267283  DT.100885665  DT.100885666  DT.100885676  DT.100885671  DT.100885678  DT.102839895  DT.102839897 
    DT.121267295  DT.121267422  DT.121341580  DT.97815824  DT.97864354  DT.99947798  DT.121341522  DT.75141672 

    24/961 AceView cDNA sequences (see all 961):

    AW196707 BQ631819 BE269055 BM551071 BQ001426 CB151058 BM475354 CA311259 
    AF069765 BX953185 BM765559 BM995107 BG120666 BQ653984 BQ212817 AA312492 
    AW341488 BU633628 BX284054 BF939609 BM988842 CA422529 AU103981 N47076 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SRP72    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19
    SP1:                                            -           -     -                                                           -               
    SP2:                                            -                                                                                             
    SP3:                                                                                                                                          
    SP4:                                                                                                                                          


    ECgene alternative splicing isoforms for SRP72

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SRP72 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACTTTCTAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SRP72 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SRP72

    SOURCE GeneReport for Unigene cluster: Hs.237825
        SABiosciences Custom PCR Arrays for SRP72
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRP72

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SRP72 gene from 9/29 species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Srp721 , 5 signal recognition particle 721, 5 89.77(n)1
    96.27(a)1
      5 (41.45 cM)5
    666611  NM_025691.11  NP_079967.11 
     769746835 
    chicken
    (Gallus gallus)
    Aves SRP721 signal recognition particle 72kDa 77.26(n)
    87.16(a)
      422626  NM_001006449.1  NP_001006449.1 
    lizard
    (Anolis carolinensis)
    Reptilia SRP726
    --
    85(a)
    1 ↔ 1
    GL343257.1(1723173-1747649)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.51372 Xenopus laevis transcribed sequence with moderate similarity more 76.79(n)    BU909646.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb49d082 Danio rerio cDNA clone IMAGE3815935, partial cds 74.99(n)    BC055254.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Srp721 Signal recognition particle protein 72 48.41(n)
    42.7(a)
      42439  NM_142641.2  NP_650898.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F08D12.13
    CELE_F08D12.11
    signal recognition particle protein3
    Protein F08D12.11
    27(a)3
    44.27(n)1
    32.16(a)1
      II(2787479-2793199)3
    1736251  NM_061965.41  NP_494366.21 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G676801 signal recognition particle subunit SRP72 46.61(n)
    34.31(a)
      843093  NM_105436.3  NP_176936.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g08890001 hypothetical protein 46(n)
    33.93(a)
      4324904  NM_001051579.1  NP_001045044.1 


    ENSEMBL Gene Tree for SRP72 (if available)
    TreeFam Gene Tree for SRP72 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SRP72 gene

    SRP72 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SRP72
    PGOHUM00000234929 PGOHUM00000243430


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Human Gene Mutation Database (HGMD): SRP72
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SRP72 for disorders           About GeneDecksing

    OMIM gene information: 602122    OMIM disorders: --

    UniProtKB/Swiss-Prot: SRP72_HUMAN, O76094
  • Defects in SRP72 are the cause of bone marrow failure, familial (BMFF) [MIM:614675]. BMFF is an autosomal
  • dominant disease characterized by aplastic anemia and myelodysplasia resulting from bone marrow failure. Aplastic
    anemia is a form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.
    Myelodysplasia is a clonal hematopoietic stem cell disorder in which immature cells in the bone marrow become
    malformed and dysfunctional

    6 diseases for SRP72:    About MalaCards
    anterior spinal artery syndrome    iritis    pellagra    glomerulopathy
    pancreatic cancer    pancreatitis

    2 diseases from the University of Copenhagen DISEASES database for SRP72:
    Anterior spinal artery syndrome     Iritis

    Export disorders for SRP72 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SRP72 gene, integrated from 9 sources (see all 53):
    (articles sorted by number of sources associating them with SRP72)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A truncated isoform of Ca2+/calmodulin-dependent protein kinase II expressed in human islets of Langerhans may result from trans- splicing. (PubMed id 9224693)1, 3, 9 Breen M.A. and Ashcroft S.J. (1997)
    2. Exome sequencing identifies autosomal-dominant SRP72 m utations associated with familial aplasia and myelodysplasia. (PubMed id 22541560)1, 2 Kirwan M....Dokal I. (2012)
    3. The 72-kDa component of signal recognition particle i s cleaved during apoptosis. (PubMed id 9857079)1, 3 Utz P.J....Anderson P. (1998)
    4. Protein SRP68 of human signal recognition particle: identification of the RNA and SRP72 binding domains. (PubMed id 16672232)1, 9 Iakhiaeva E....Zwieb C. (2006)
    5. The Signal Recognition Particle Database (SRPDB). (PubMed id 9399828)1, 9 Larsen N....Zwieb C. (1998)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    9. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. (PubMed id 22837378)1 Wilk J.B....Stricker B.H. (2012)
    10. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6731 HGNC: 11303 AceView: PAICSandSRP72 Ensembl:ENSG00000174780 euGenes: HUgn6731
    ECgene: SRP72 Kegg: 6731 H-InvDB: SRP72

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SRP72 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Signal_recognition_particle

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SRP72 gene:
    Search GeneIP for patents involving SRP72

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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