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Aliases for SRGAP2D Gene

Aliases for SRGAP2D Gene

  • SLIT-ROBO Rho GTPase Activating Protein 2D (Pseudogene) 2 3 5
  • SLIT-ROBO Rho GTPase Activating Protein 2D 2

External Ids for SRGAP2D Gene

Previous GeneCards Identifiers for SRGAP2D Gene

  • GC01U903446

Summaries for SRGAP2D Gene

Entrez Gene Summary for SRGAP2D Gene

  • This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2B locus. This duplicated locus lacks an internal exon, and thus this gene copy may not be functional. Expression of this locus appears to be much lower than the similar SLIT-ROBO Rho GTPase activating protein 2C (SRGAP2C) locus. The SRGAP2C locus has been shown to encode a protein that functions antagonistically to SLIT-ROBO Rho GTPase activating protein 2 in cortical neuron development. [provided by RefSeq, May 2014]

GeneCards Summary for SRGAP2D Gene

SRGAP2D (SLIT-ROBO Rho GTPase Activating Protein 2D (Pseudogene)) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SRGAP2D Gene

Genomics for SRGAP2D Gene

Regulatory Elements for SRGAP2D Gene

Promoters for SRGAP2D Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SRGAP2D on UCSC Golden Path with GeneCards custom track

Genomic Location for SRGAP2D Gene

Chromosome:
1
Start:
143,972,639 bp from pter
End:
144,069,704 bp from pter
Size:
97,066 bases
Orientation:
Plus strand

Genomic View for SRGAP2D Gene

Genes around SRGAP2D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SRGAP2D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SRGAP2D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SRGAP2D Gene

Proteins for SRGAP2D Gene

Post-translational modifications for SRGAP2D Gene

No Post-translational modifications

No data available for DME Specific Peptides for SRGAP2D Gene

Domains & Families for SRGAP2D Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SRGAP2D Gene

Function for SRGAP2D Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SRGAP2D Gene

Localization for SRGAP2D Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SRGAP2D Gene

Pathways & Interactions for SRGAP2D Gene

SuperPathways for SRGAP2D Gene

No Data Available

Interacting Proteins for SRGAP2D Gene

Gene Ontology (GO) - Biological Process for SRGAP2D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SRGAP2D Gene

Drugs & Compounds for SRGAP2D Gene

No Compound Related Data Available

Transcripts for SRGAP2D Gene

mRNA/cDNA for SRGAP2D Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SRGAP2D Gene

No ASD Table

Relevant External Links for SRGAP2D Gene

GeneLoc Exon Structure for
SRGAP2D
ECgene alternative splicing isoforms for
SRGAP2D

Expression for SRGAP2D Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SRGAP2D Gene

Orthologs for SRGAP2D Gene

Evolution for SRGAP2D Gene

ENSEMBL:
Gene Tree for SRGAP2D (if available)
TreeFam:
Gene Tree for SRGAP2D (if available)

No data available for Orthologs for SRGAP2D Gene

Paralogs for SRGAP2D Gene

No data available for Paralogs for SRGAP2D Gene

Variants for SRGAP2D Gene

Sequence variations from dbSNP and Humsavar for SRGAP2D Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs916505 -- 144,066,162(+) TGCAG(A/G)CAAGA intron-variant
rs1048832 -- 144,069,652(-) ATATG(C/T)TTAAA nc-transcript-variant
rs1048833 -- 144,069,597(-) GCAGT(A/G)TCCTA nc-transcript-variant
rs1055121 -- 144,057,435(+) TCACC(A/G)AAATA intron-variant
rs1055124 -- 144,057,524(+) CCAAG(C/T)GTTTT intron-variant

Relevant External Links for SRGAP2D Gene

HapMap Linkage Disequilibrium report
SRGAP2D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SRGAP2D Gene

Disorders for SRGAP2D Gene

Relevant External Links for SRGAP2D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SRGAP2D

No disorders were found for SRGAP2D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SRGAP2D Gene

Publications for SRGAP2D Gene

  1. Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication. (PMID: 22559943) Dennis M.Y. … Eichler E.E. (Cell 2012) 2 3 67

Products for SRGAP2D Gene

Sources for SRGAP2D Gene

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