Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SRGAP2C Gene

protein-coding   GIFtS: 27
GCID: GC01P121091

SLIT-ROBO Rho GTPase Activating Protein 2C

(Previous name: SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1)
(Previous symbol: SRGAP2P1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
SLIT-ROBO Rho GTPase Activating Protein 2C1 2
SRGAP2P11 2 3
SLIT-ROBO Rho GTPase Activating Protein 2 Pseudogene 11 2 3
SLIT-ROBO Rho GTPase-Activating Protein 2C2

External Ids:    HGNC: 305841   Entrez Gene: 6534642   Ensembl: ENSG000001719437   OMIM: 6147045   UniProtKB: P0DJJ03   

Export aliases for SRGAP2C gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SRGAP2C Gene:
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus
resulted from segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2B locus. The encoded protein
lacks the GTPase activating protein domain compared to proteins encoded by SLIT-ROBO Rho GTPase activating
protein 2, and acts antagonistically to these proteins in cortical neuron development. (provided by RefSeq, Dec
2012)

GeneCards Summary for SRGAP2C Gene: 
SRGAP2C (SLIT-ROBO Rho GTPase activating protein 2C) is a protein-coding gene. Diseases associated with SRGAP2C include neuronitis, and cerebritis. GO annotations related to this gene include protein heterodimerization activity and protein homodimerization activity.

UniProtKB/Swiss-Prot: SRG2C_HUMAN, P0DJJ0
Function: Involved in dendritic spine maturation through interaction with and inhibition of SRGAP2. Reduces the
rate of spine maturation and indirectly increases neuronal migration. Changes dendritic spine morphology and
density and may have implications for cognition, learning and memory




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  NT_077389.3  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SRGAP2C
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SRGAP2C

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRGAP2C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p11.2   Ensembl cytogenetic band:  1p11.2   HGNC cytogenetic band: 1p11.2

SRGAP2C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRGAP2C gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P121091:  view genomic region     (about GC identifiers)

Start:
121,090,793 bp from pter      End:
121,134,742 bp from pter
Size:
43,950 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SRG2C_HUMAN, P0DJJ0 (See protein sequence)
Recommended Name: SLIT-ROBO Rho GTPase-activating protein 2C  
Size: 459 amino acids; 53484 Da
Subunit: Homodimer. Interacts with SRGAP2; formation of the heterodimer alters SRGAP2 function
Miscellaneous: This is one of the 3 duplications of the ancestral gene SRGAP2 which has undergone human-specific
segmental gene duplications. The appearance of SRGAP2C in the human genome is estimated to 2,4 million years ago,
corresponding to the beginning of neocortex expansion in human evolution and it may have played an important role
in this process. 2 other copies of SRGAP2, SRGAP2B and SRGAP2D, were identified in some individuals but most
probably do not produce a functional protein (PubMed:22559944). SRGAP2C is the only copy to be fixed at a diploid
state in the genome and to exhibit strong mRNA expression. A cDNA specific for that gene was used in the
functional study (PubMed:22559944)
Caution: The retained sequence for SRGAP2C might not align to the reference genome due to assembly discrepancies

Explore the universe of human proteins at neXtProt for SRGAP2C: NX_P0DJJ0

SRGAP2C Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --

REFSEQ proteins: NP_001258801.1  
Human Recombinant Protein Products for SRGAP2C: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
OriGene Custom MassSpec 
OriGene Custom Protein Services for SRGAP2C
GenScript Custom Purified and Recombinant Proteins Services for SRGAP2C
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp. 


SRGAP2C Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for SRGAP2C
GenScript Custom Superior Antibodies Services for SRGAP2C
Search for Antibodies for SRGAP2C at Abcam
Browse Antibodies at Cloud-Clone Corp. 
Search ThermoFisher Antibodies for SRGAP2C
Search LSBio for Antibodies for SRGAP2C 

Assay Products for SRGAP2C: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for SRGAP2C
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for SRGAP2C
Browse Enzo Life Sciences for kits & assays
Browse ELISAs at Cloud-Clone Corp. 
Browse CLIAs at Cloud-Clone Corp.


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro protein domain:
 IPR001060 FCH_dom

Graphical View of Domain Structure for InterPro Entry P0DJJ0

ProtoNet protein and cluster: P0DJJ0

UniProtKB/Swiss-Prot: SRG2C_HUMAN, P0DJJ0
Similarity: Contains 1 FCH domain


SRGAP2C for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: SRG2C_HUMAN, P0DJJ0
Function: Involved in dendritic spine maturation through interaction with and inhibition of SRGAP2. Reduces the
rate of spine maturation and indirectly increases neuronal migration. Changes dendritic spine morphology and
density and may have implications for cognition, learning and memory

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0042803protein homodimerization activity IPI--
GO:0046982protein heterodimerization activity IPI--
     
SRGAP2C for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for SRGAP2C 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SRGAP2C

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SRGAP2C 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SRGAP2C 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SRGAP2C
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SRGAP2C
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for SRGAP2C
Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SRGAP2C

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for SRGAP2C
Sirion Biotech Customized adenovirus for overexpression of SRGAP2C

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for SRGAP2C
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for SRGAP2C
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SRGAP2C
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRGAP2C
Sirion Biotech Customized lentivirus for stable overexpression of SRGAP2C 
                     Customized lentivirus expression plasmids for stable overexpression of SRGAP2C 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for SRGAP2C
Search LifeMap BioReagents cell lines for SRGAP2C
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRGAP2C


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SRGAP2C

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0021816extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration IDA--
GO:0051490negative regulation of filopodium assembly IDA--
GO:0061000negative regulation of dendritic spine development IDA--
GO:2001224positive regulation of neuron migration IDA--

SRGAP2C for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SRGAP2C (SRG2C)

Search CenterWatch for drugs/clinical trials and news about SRGAP2C / SRG2C

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SRGAP2C gene: 
NM_001271872.1  

Unigene Cluster for SRGAP2C:

SLIT-ROBO Rho GTPase activating protein 2C
Hs.523529  [show with all ESTs]
Unigene Representative Sequence: BC017972
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000304465 ENST00000367123(uc001eis.2)
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SRGAP2C
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SRGAP2C
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for SRGAP2C
Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SRGAP2C
Clone
Products:
     
OriGene clones in human, mouse for SRGAP2C
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for SRGAP2C
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SRGAP2C
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRGAP2C
Sirion Biotech Customized lentivirus for stable overexpression of SRGAP2C 
                     Customized lentivirus expression plasmids for stable overexpression of SRGAP2C 
Primer
Products:
    
Browse OriGene qPCR
Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat SRGAP2C
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRGAP2C
  Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRGAP2C

Additional mRNA sequence: 

BC017972.1 DQ786199.1 

10 DOTS entries:

DT.412097  DT.121370749  DT.121370688  DT.121460324  DT.121426206  DT.434729  DT.92420779  DT.95254487 
DT.120678401  DT.95254488 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --


Genevestigator expression for SRGAP2C

SOURCE GeneReport for Unigene cluster: Hs.523529

UniProtKB/Swiss-Prot: SRG2C_HUMAN, P0DJJ0
Tissue specificity: Ubiquitously expressed with higher expression in cerebellum. Probably expressed in fetal and
adult neurons (at protein level)

    SABiosciences Custom PCR Arrays for SRGAP2C
Primer
Products:
Browse OriGene qPCR
Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat SRGAP2C
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRGAP2C
Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRGAP2C
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRGAP2C

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
  --

ENSEMBL Gene Tree for SRGAP2C (if available)
TreeFam Gene Tree for SRGAP2C (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for SRGAP2C gene
6 SIMAP similar genes for SRGAP2C using alignment to 1 protein entry:     SRG2C_HUMAN:
SRGAP2    SRGAP1    SRGAP3    KIAA1156    C1    ARHGAP4

SRGAP2C for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/260 SNPs in SRGAP2C are shown (see all 260)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs3761911971,2
C--120752452(+) GAACCC/TGGAGG 1 -- int10--------
rs770438961,2
F--120755968(+) TACTAG/AAAATA 1 -- int12Minor allele frequency- A:0.50NA 4
rs748212811,2
F--120755983(+) AATTAG/TCCAGG 1 -- int11Minor allele frequency- T:0.50NA 4
rs798581001,2
F--120755990(+) AGGCGG/TTAGTG 1 -- int12Minor allele frequency- T:0.50NA 4
rs776483021,2
C--120756031(+) TGAGGG/CAGGAG 1 -- int13Minor allele frequency- C:0.00NA 6
rs3701749951,2
C--120758370(+) CTACCC/TCCTCA 1 -- int10--------
rs3683966551,2
C--120759880(+) GAAAA-/CA    
   CTGAA
ACTGA
1 -- int10--------
rs3750561831,2
C--120760312(+) ATGAT-/AAA   
   
/AAAA
AAAAA
2 -- int1 cds10--------
rs3726304471,2
C--120762990(+) GCACA-/CT    
   TGAGC
CTTAG
1 -- int10--------
rs3720368501,2
C--120763497(+) AAAGT-/AGAAGAAG 1 -- int10--------

HapMap Linkage Disequilibrium report for SRGAP2C (121090793 - 121134742 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for SRGAP2C: --
SABiosciences Cancer Mutation PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing SRGAP2C
DNA2.0 Custom Variant and Variant Library Synthesis for SRGAP2C

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 614704    OMIM disorders: --

2 diseases for SRGAP2C:    About MalaCards
neuronitis    cerebritis


SRGAP2C for disorders           About GeneDecksing


Export disorders for SRGAP2C gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for SRGAP2C gene integrated from 9 sources:
(articles sorted by number of sources associating them with SRGAP2C)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication. (PubMed id 22559943)1, 2, 3 Dennis M.Y....Eichler E.E. (2012)
  2. Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation. (PubMed id 22559944)1, 2, 3 Charrier C....Polleux F. (2012)
  3. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
  4. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PubMed id 17903296)1 Kiel D.P....Karasik D. (2007)
  5. Lineage-specific gene duplication and loss in human and great ape evolution. (PubMed id 15252450)1 Fortna A....Sikela J.M. (2004)
  6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 653464 HGNC: 30584 Ensembl:ENSG00000171943 euGenes: HUgn653464 ECgene: SRGAP2C
H-InvDB: SRGAP2C

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for SRGAP2C Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for SRGAP2C gene:
Search GeneIP for patents involving SRGAP2C

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
 Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SRGAP2C  
 Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for SRGAP2C  
 Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for SRGAP2C   OriGene Custom Protein Services for SRGAP2C  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SRGAP2C
 QIAGEN SeqTarget long-range PCR primers for resequencing SRGAP2C
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRGAP2C
 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SRGAP2C
 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRGAP2C
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRGAP2C
 GenScript Custom Purified and Recombinant Proteins Services for SRGAP2C GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for SRGAP2C
 GenScript Custom Assay Services for SRGAP2C GenScript Custom Superior Antibodies Services for SRGAP2C
 GenScript Custom overexpressing Cell Line Services for SRGAP2C CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Search Regulatory tfbs for SRGAP2C
 Search Chromatin IP Primers for SRGAP2C
 Search RT2 qPCR Primer Assays in human, mouse, rat SRGAP2C
 Search GNC Networks for SRGAP2C
 SABiosciences Custom PCR Arrays for SRGAP2C
 Search Tocris compounds for SRGAP2C (SRG2C)
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Biologicals
 Novus Tissue Slides
 Search for Antibodies for SRGAP2C at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for SRGAP2C
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.
 Search LifeMap BioReagents cell lines for SRGAP2C
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRGAP2C
 Browse SwitchGear 3'UTR luciferase reporter plasmids for SRGAP2C
 Browse SwitchGear Promoter luciferase reporter plasmids for SRGAP2C
 Search ThermoFisher Antibodies for SRGAP2C
 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SRGAP2C
 inGenious Targeting Laboratory - Custom generated mouse model solutions for SRGAP2C
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SRGAP2C
Customized:
 lentivirus for stable overexpression of SRGAP2C
 lentivirus expression plasmids for stable overexpression of SRGAP2C
 adenovirus for overexpression of SRGAP2C
 Search LSBio for Antibodies for SRGAP2C
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category
(GIFtS: 73)
transforming growth factor, beta 1
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      SRGAP2C gene at Home site.
hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4