Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SREK1IP1 Gene

Aliases for SREK1IP1 Gene

  • SREK1-Interacting Protein 1 2 3 4
  • SFRS12-Interacting Protein 1 2 3 4
  • Splicing Regulatory Protein Of 18 KDa 3 4
  • P18 Splicing Regulatory Protein 2 3
  • SFRS12IP1 3 4
  • P18SRP 3 4
  • Protein SFRS12IP1 3
  • Protein SREK1IP1 3

External Ids for SREK1IP1 Gene

Previous HGNC Symbols for SREK1IP1 Gene

  • SFRS12IP1

Previous GeneCards Identifiers for SREK1IP1 Gene

  • GC05M064013

Summaries for SREK1IP1 Gene

GeneCards Summary for SREK1IP1 Gene

SREK1IP1 (SREK1-Interacting Protein 1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for SREK1IP1 Gene

  • Possible splicing regulator involved in the control of cellular survival

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SREK1IP1 Gene

Genomics for SREK1IP1 Gene

Genomic Location for SREK1IP1 Gene

Start:
64,718,144 bp from pter
End:
64,768,685 bp from pter
Size:
50,542 bases
Orientation:
Minus strand

Genomic View for SREK1IP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SREK1IP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SREK1IP1 Gene

No data available for Regulatory Elements for SREK1IP1 Gene

Proteins for SREK1IP1 Gene

  • Protein details for SREK1IP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N9Q2-SR1IP_HUMAN
    Recommended name:
    Protein SREK1IP1
    Protein Accession:
    Q8N9Q2
    Secondary Accessions:
    • Q32NC8

    Protein attributes for SREK1IP1 Gene

    Size:
    155 amino acids
    Molecular mass:
    18177 Da
    Quaternary structure:
    • Interacts with SREK1/SFRS12.
    SequenceCaution:
    • Sequence=AAI08717.1; Type=Frameshift; Positions=79; Evidence={ECO:0000305};

neXtProt entry for SREK1IP1 Gene

Proteomics data for SREK1IP1 Gene at MOPED

Post-translational modifications for SREK1IP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SREK1IP1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SREK1IP1 Gene

Domains for SREK1IP1 Gene

Protein Domains for SREK1IP1 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SREK1IP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N9Q2

UniProtKB/Swiss-Prot:

SR1IP_HUMAN :
  • Q8N9Q2
Similarity:
  • Contains 1 CCHC-type zinc finger.
genes like me logo Genes that share domains with SREK1IP1: view

No data available for Gene Families for SREK1IP1 Gene

Function for SREK1IP1 Gene

Molecular function for SREK1IP1 Gene

UniProtKB/Swiss-Prot Function: Possible splicing regulator involved in the control of cellular survival
UniProtKB/Swiss-Prot Induction: Down-regulated in the brains of Alzheimer disease patients.

Gene Ontology (GO) - Molecular Function for SREK1IP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with SREK1IP1: view

Phenotypes for SREK1IP1 Gene

GenomeRNAi human phenotypes for SREK1IP1:
genes like me logo Genes that share phenotypes with SREK1IP1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SREK1IP1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SREK1IP1 Gene

Localization for SREK1IP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SREK1IP1 Gene

Pathways for SREK1IP1 Gene

SuperPathways for SREK1IP1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SREK1IP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006397 mRNA processing IEA --
GO:0008380 RNA splicing IEA --
genes like me logo Genes that share ontologies with SREK1IP1: view

No data available for Pathways by source for SREK1IP1 Gene

Transcripts for SREK1IP1 Gene

Unigene Clusters for SREK1IP1 Gene

SREK1-interacting protein 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SREK1IP1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SREK1IP1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SREK1IP1 Gene

No ASD Table

Relevant External Links for SREK1IP1 Gene

GeneLoc Exon Structure for
SREK1IP1
ECgene alternative splicing isoforms for
SREK1IP1

Expression for SREK1IP1 Gene

mRNA expression in normal human tissues for SREK1IP1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SREK1IP1 Gene

SOURCE GeneReport for Unigene cluster for SREK1IP1 Gene Hs.69504

genes like me logo Genes that share expressions with SREK1IP1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SREK1IP1 Gene

Orthologs for SREK1IP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SREK1IP1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SREK1IP1 35
  • 99.57 (n)
  • 100 (a)
SREK1IP1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SREK1IP1 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SREK1IP1 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Srek1ip1 16
Srek1ip1 36
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
OneToMany
-- 36
  • 85 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SREK1IP1 36
  • 83 (a)
OneToOne
chicken
(Gallus gallus)
Aves SREK1IP1 36
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SREK1IP1 36
  • 70 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.7776 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.17599 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2618 35
zebrafish
(Danio rerio)
Actinopterygii srek1ip1 36
  • 56 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG3918 36
  • 18 (a)
OneToOne
Species with no ortholog for SREK1IP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SREK1IP1 Gene

ENSEMBL:
Gene Tree for SREK1IP1 (if available)
TreeFam:
Gene Tree for SREK1IP1 (if available)

Paralogs for SREK1IP1 Gene

Pseudogenes.org Pseudogenes for SREK1IP1 Gene

genes like me logo Genes that share paralogs with SREK1IP1: view

No data available for Paralogs for SREK1IP1 Gene

Variants for SREK1IP1 Gene

Sequence variations from dbSNP and Humsavar for SREK1IP1 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs166706 -- 64,745,764(-) AGGGT(C/T)GCTTT intron-variant
rs188027 -- 64,745,914(-) ttgct(A/G)tAAGA intron-variant
rs202117 -- 64,757,927(-) acgcc(A/C)ctgca intron-variant
rs275819 -- 64,728,154(-) AAGAA(A/G)AAAGA synonymous-codon, reference
rs275820 -- 64,744,996(-) CCTCA(A/C)GTAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SREK1IP1 Gene

Variant ID Type Subtype PubMed ID
dgv6083n71 CNV Gain 21882294
esv2752074 CNV Gain 17911159

Relevant External Links for SREK1IP1 Gene

HapMap Linkage Disequilibrium report
SREK1IP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SREK1IP1 Gene

Disorders for SREK1IP1 Gene

No disorders were found for SREK1IP1 Gene.

No data available for UniProtKB/Swiss-Prot for SREK1IP1 Gene

Publications for SREK1IP1 Gene

  1. The splicing regulatory protein p18SRP is down-regulated in Alzheimer's disease brain. (PMID: 15456940) Heese K. … Sawada T. (J. Mol. Neurosci. 2004) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for SREK1IP1 Gene

Sources for SREK1IP1 Gene

Back to Top

Content