Aliases for SREK1 Gene
External Ids for SREK1 Gene
Previous HGNC Symbols for SREK1 Gene
Previous GeneCards Identifiers for SREK1 Gene
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
GeneCards Summary for SREK1 Gene
SREK1 (Splicing Regulatory Glutamic Acid And Lysine Rich Protein 1) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is SRSF11.
UniProtKB/Swiss-Prot for SREK1 Gene
Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity).