Aliases for SRD5A1 Gene
External Ids for SRD5A1 Gene
Previous GeneCards Identifiers for SRD5A1 Gene
Steroid 5-alpha-reductase (EC 220.127.116.11) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]
GeneCards Summary for SRD5A1 Gene
SRD5A1 (Steroid-5-Alpha-Reductase, Alpha Polypeptide 1 (3-Oxo-5 Alpha-Steroid Delta 4-Dehydrogenase Alpha 1)) is a Protein Coding gene. Diseases associated with SRD5A1 include chronic laryngitis and 5-alpha reductase deficiency. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include electron carrier activity and cholestenone 5-alpha-reductase activity.
UniProtKB/Swiss-Prot for SRD5A1 Gene
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology