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SRCRB4D Gene

protein-coding   GIFtS: 45
GCID: GC07M076018

Scavenger Receptor Cysteine Rich Domain Containing, Group...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Scavenger Receptor Cysteine Rich Domain Containing, Group B (4
Domains)1 2
     SRCRB-S4D2
Scavenger Receptor Cysteine-Rich Protein SRCRB-S4D1 2     SSC4D2
S4-SRCRB2 3     Scavenger Receptor Cysteine-Rich Domain-Containing Group B Protein2
S4D-SRCRB2     

External Ids:    HGNC: 144611   Entrez Gene: 1368532   Ensembl: ENSG000001467007   OMIM: 6076395   UniProtKB: Q8WTU23   

Export aliases for SRCRB4D gene to outside databases

Previous GC identifers: GC07M074554 GC07M075616 GC07M075630 GC07M075663 GC07M075856 GC07M071105


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SRCRB4D Gene:
The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface
and/or secreted proteins, some of which are involved in the development of the immune system and the regulation
of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines
that give rise to a well-defined intradomain disulfide-bond pattern.(supplied by OMIM, Apr 2004)

GeneCards Summary for SRCRB4D Gene:
SRCRB4D (scavenger receptor cysteine rich domain containing, group B (4 domains)) is a protein-coding gene. Diseases associated with SRCRB4D include williams-beuren syndrome, and hepatitis b. GO annotations related to this gene include scavenger receptor activity. An important paralog of this gene is LOXL2.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NC_018918.2  NT_007933.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the SRCRB4D gene promoter:
         NF-1/L   NF-1   HTF   HNF-4alpha2   AP-2gamma   E47   HNF-4alpha1   MZF-1   c-Rel   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SRCRB4D promoter sequence
   Search Chromatin IP Primers for SRCRB4D

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SRCRB4D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q11.23   Ensembl cytogenetic band:  7q11.23   HGNC cytogenetic band: 7q11.23

SRCRB4D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRCRB4D gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M076018:  view genomic region     (about GC identifiers)

Start:
76,018,646 bp from pter      End:
76,039,012 bp from pter
Size:
20,367 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 75,351,710-75,372,076     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SRB4D_HUMAN, Q8WTU2 (See protein sequence)
Recommended Name: Scavenger receptor cysteine-rich domain-containing group B protein precursor  
Size: 575 amino acids; 60819 Da
Sequence caution: Sequence=AAH15651.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=BAD18764.1;
Type=Frameshift; Positions=25;
Secondary accessions: Q2HIZ5 Q6ZMG3 Q96BF5
Alternative splicing: 2 isoforms:  Q8WTU2-1   Q8WTU2-2   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for SRCRB4D: NX_Q8WTU2

Explore proteomics data for SRCRB4D at MOPED


See SRCRB4D Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_542782.1  
ENSEMBL proteins: 
 ENSP00000275560  

SRCRB4D Human Recombinant Protein Products:

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Abcam antibodies for SRCRB4D
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LSBio Antibodies in human, mouse, rat for SRCRB4D

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Cloud-Clone Corp. ELISAs for SRCRB4D
Cloud-Clone Corp. CLIAs for SRCRB4D


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR001190 SRCR
 IPR017448 Srcr_rcpt-rel

Graphical View of Domain Structure for InterPro Entry Q8WTU2

ProtoNet protein and cluster: Q8WTU2

UniProtKB/Swiss-Prot: SRB4D_HUMAN, Q8WTU2
Similarity: Contains 4 SRCR domains


SRCRB4D for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: SRB4D_HUMAN, Q8WTU2
Induction: Not induced by a combination of IL1A/interleukin-1 alpha, IL6/interleukin-6 and dexamethasone

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005044scavenger receptor activity IEA--
     
SRCRB4D for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SRCRB4D
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SRCRB4D
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SRCRB4D

miRNA
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Block miRNA regulation of human, mouse, rat SRCRB4D using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SRCRB4D (see all 17):
hsa-miR-3200-5p hsa-miR-642a hsa-miR-4254 hsa-miR-1271 hsa-miR-29c hsa-miR-29a hsa-miR-767-5p hsa-miR-650
SwitchGear 3'UTR luciferase reporter plasmidSRCRB4D 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for SRCRB4D
Predesigned siRNA for gene silencing in human, mouse, rat SRCRB4D

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for SRCRB4D

Clone
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OriGene clones in human, mouse for SRCRB4D (see all 7)
OriGene ORF clones in mouse, rat for SRCRB4D
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: SRCRB4D (NM_080744)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SRCRB4D
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRCRB4D

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRCRB4D


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
SRB4D_HUMAN, Q8WTU2: Secreted (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular3
plasma membrane3
cytosol2
nucleus2

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region IEA--
GO:0016020membrane IEA--

SRCRB4D for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SRCRB4D
Interactions:

    Search GeneGlobe Interaction Network for SRCRB4D

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for SRCRB4D (SRB4D)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for SRCRB4D gene: 
NM_080744.1  

Unigene Cluster for SRCRB4D:

Scavenger receptor cysteine rich domain containing, group B (4 domains)
Hs.567684  [show with all ESTs]
Unigene Representative Sequence: NM_080744
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000492979(uc003ufa.3) ENST00000275560(uc003ufb.3)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat SRCRB4D using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SRCRB4D (see all 17):
hsa-miR-3200-5p hsa-miR-642a hsa-miR-4254 hsa-miR-1271 hsa-miR-29c hsa-miR-29a hsa-miR-767-5p hsa-miR-650
SwitchGear 3'UTR luciferase reporter plasmidSRCRB4D 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for SRCRB4D
Predesigned siRNA for gene silencing in human, mouse, rat SRCRB4D
Clone
Products:
     
OriGene clones in human, mouse for SRCRB4D (see all 7)
OriGene ORF clones in mouse, rat for SRCRB4D
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: SRCRB4D (NM_080744)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SRCRB4D
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRCRB4D
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for SRCRB4D
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SRCRB4D
  QuantiTect SYBR Green Assays in human, mouse, rat SRCRB4D
  QuantiFast Probe-based Assays in human, mouse, rat SRCRB4D

Additional mRNA sequence: 

AJ312755.1 AK172783.1 BC015651.2 BC113840.1 

3 DOTS entries:

DT.100663260  DT.40126015  DT.40302492 

24 AceView cDNA sequences:

AJ312755 BG683667 NM_080744 CR620510 CD635956 BU629327 BX399856 AI677867 
CD635947 BF115652 CD635952 CD635945 BG682948 BI762349 AW452662 AK172783 
AI142037 AA878093 BQ959400 BC015651 AI948805 CD635954 BF055097 AW874103 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for SRCRB4D    About this scheme

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c
SP1:        -     -     -                           
SP2:                    -                           
SP3:                                                


ECgene alternative splicing isoforms for SRCRB4D

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SRCRB4D expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACCCAGCCCG
SRCRB4D Expression
About this image

SRCRB4D Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

SRCRB4D Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.567684
    Custom PCR Arrays for SRCRB4D
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for SRCRB4D
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SRCRB4D
QuantiTect SYBR Green Assays in human, mouse, rat SRCRB4D
QuantiFast Probe-based Assays in human, mouse, rat SRCRB4D
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRCRB4D

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for SRCRB4D gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Srcrb4d1 , 5 scavenger receptor cysteine rich domain containing, more1, 5 83.92(n)1
88.46(a)1
  5 (75.60 cM)5
1092671  NM_001160366.11  NP_001153838.11 
 1359602115 
chicken
(Gallus gallus)
Aves SRCRB4D1 scavenger receptor cysteine rich domain containing, more 68.78(n)
65.26(a)
  771260  XM_003642422.2  XP_003642470.2 
lizard
(Anolis carolinensis)
Reptilia SRCRB4D6
scavenger receptor cysteine rich domain containing...
59(a)
1 ↔ 1
GL343889.1(8918-27314)
tropical clawed frog
(Xenopus tropicalis)
Amphibia srcrb4d1 scavenger receptor cysteine rich domain containing, more 60.95(n)
62.96(a)
  100488350  XM_002933828.2  XP_002933874.2 
zebrafish
(Danio rerio)
Actinopterygii LOC1003314361 scavenger receptor cysteine-rich domain-containing more 61.61(n)
57.79(a)
  100331436  XM_002661933.3  XP_002661979.3 


ENSEMBL Gene Tree for SRCRB4D (if available)
TreeFam Gene Tree for SRCRB4D (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for SRCRB4D gene
LOXL22  CD62  CD163L12  LOXL42  CD1632  LOXL32  SSC5D2  PRSS122  
CD5L2  LOX2  LOXL12  DMBT12  
1 SIMAP similar gene for SRCRB4D using alignment to 1 protein entry:     SRB4D_HUMAN:
DMBT1

SRCRB4D for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for SRCRB4D (see all 169)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1512429661,2
--76018159(+) TGAAAC/GCCGGT 1 -- ds50010--------
rs1996015301,2
C--76018161(+) AAACCC/TGGTCA 1 -- ds50010--------
rs102509431,2
C,F,A--76018181(+) ATACAG/AAAATC 1 -- ds50012Minor allele frequency- A:0.50NA WA 4
rs102813321,2
C,F,A--76018186(+) gaaatC/Tagccg 1 -- ds50013Minor allele frequency- T:0.33NA WA 6
rs102375491,2
C,A--76018193(+) GCCGGG/ATGTGG 1 -- ds50011Minor allele frequency- A:0.50WA 2
rs352716281,2
C--76018331(+) AAAAA-/ATTTCT 1 -- ds50010--------
rs77908941,2
C,F,H--76018346(+) aaTTTC/ATTCTC 1 -- ds500113Minor allele frequency- A:0.06NS EA WA 2118
rs1393264001,2
--76018387(+) GGCCTC/TGAGCA 1 -- ds50010--------
rs77774601,2
C--76018485(+) AGGCCC/TGACAC 1 -- ds50010--------
rs1453514091,2
C--76018555(+) GAACCA/GTCCTC 1 -- ds50010--------

HapMap Linkage Disequilibrium report for SRCRB4D (76018646 - 76039012 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for SRCRB4D (see all 13):    About this table    
Variant IDTypeSubtypePubMed ID
dgv120n16CNV Deletion17901297
esv2734686CNV Deletion23290073
esv2422494CNV Duplication17116639
nsv888387CNV Loss21882294
dgv233e55CNV Loss17911159
nsv428174CNV Gain18775914
dgv232e55CNV Gain17911159
nsv528969CNV Gain19592680
essv14753CNV CNV17122850
dgv2106e1CNV Complex17122850

Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing SRCRB4D
DNA2.0 Custom Variant and Variant Library Synthesis for SRCRB4D

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 607639    OMIM disorders: --

3 diseases for SRCRB4D:    About MalaCards
williams-beuren syndrome    hepatitis b    hepatitis


SRCRB4D for disorders           About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: SRCRB4D (1 document)

Export disorders for SRCRB4D gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for SRCRB4D gene integrated from 10 sources:
(articles sorted by number of sources associating them with SRCRB4D)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning of S4D-SRCRB, a new soluble member of the group B scavenger receptor cysteine-rich family (SRCR-SF) mapping to human chromosome 7q11.23. (PubMed id 12466895)1, 2, 3, 9 Padilla O.... Lozano F. (Immunogenetics 2002)
  2. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  3. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PubMed id 21555518)1 Warnatz H.J....Yaspo M.L. (J. Biol. Chem. 2011)
  4. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 136853 HGNC: 14461 AceView: SRCRB4D Ensembl:ENSG00000146700 euGenes: HUgn136853
ECgene: SRCRB4D H-InvDB: SRCRB4D

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for SRCRB4D Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SRCRB4D gene:
Search GeneIP for patents involving SRCRB4D

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SRCRB4D  
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 Block miRNA regulation of human, mouse, rat SRCRB4D using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SRCRB4D
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SRCRB4D Predesigned siRNA for gene silencing in human, mouse, rat SRCRB4D
 QuantiFast Probe-based Assays in human, mouse, rat SRCRB4D QuantiTect SYBR Green Assays in human, mouse, rat SRCRB4D
 Custom PCR Arrays for SRCRB4D Search Chromatin IP Primers for SRCRB4D
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SRCRB4D  Search GeneGlobe Interaction Network for SRCRB4D
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 GenScript Custom Purified and Recombinant Proteins Services for SRCRB4D GenScript cDNA clones with any tag delivered in your preferred vector for SRCRB4D
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 Search Tocris compounds for SRCRB4D (SRB4D)
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
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 See all of Abcam's Antibodies, Kits and Proteins for SRCRB4D
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 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for SRCRB4D
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 Browse ESI BIO Cell Lines and PureStem Progenitors for SRCRB4D
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRCRB4D
 SwitchGear 3'UTR luciferase reporter plasmids for SRCRB4D
 SwitchGear Promoter luciferase reporter plasmids for SRCRB4D
 Search ThermoFisher Antibodies for SRCRB4D
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRCRB4D
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SRCRB4D
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SRCRB4D
 LSBio Antibodies in human, mouse, rat for SRCRB4D
Customized transgenic rodents for:
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 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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