Aliases for SRCIN1 Gene
External Ids for SRCIN1 Gene
Previous GeneCards Identifiers for SRCIN1 Gene
GeneCards Summary for SRCIN1 Gene
SRCIN1 (SRC Kinase Signaling Inhibitor 1) is a Protein Coding gene. Diseases associated with SRCIN1 include Sclerosing Keratitis and Punctate Epithelial Keratoconjunctivitis. Among its related pathways are Cytoskeletal Signaling and Adhesion. GO annotations related to this gene include protein kinase binding and protein domain specific binding. An important paralog of this gene is KIAA1217.
UniProtKB/Swiss-Prot for SRCIN1 Gene
Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.