Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SRBD1 Gene

protein-coding   GIFtS: 52
GCID: GC02M045615

S1 RNA Binding Domain 1

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
S1 RNA Binding Domain 11 2
H_NH0576F01.12
WUGSC:H_NH0576F01.12
S1 RNA-Binding Domain-Containing Protein 12

External Ids:    HGNC: 255211   Entrez Gene: 551332   Ensembl: ENSG000000687847   UniProtKB: Q8N5C63   

Export aliases for SRBD1 gene to outside databases

Previous GC identifers: GC02M045469 GC02M045354


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for SRBD1 Gene:
SRBD1 (S1 RNA binding domain 1) is a protein-coding gene. GO annotations related to this gene include hydrolase activity, acting on ester bonds and RNA binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_022184.16  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SRBD1 gene promoter:
         Oct-B1   TBP   oct-B3   oct-B2   E4BP4   RORalpha1   POU2F1   Nkx6-1   TFIID   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSRBD1 promoter sequence
   Search Chromatin IP Primers for SRBD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SRBD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p21   Ensembl cytogenetic band:  2p21   HGNC cytogenetic band: 2p21

SRBD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRBD1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M045615:  view genomic region     (about GC identifiers)

Start:
45,615,819 bp from pter      End:
45,839,304 bp from pter
Size:
223,486 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SRBD1_HUMAN, Q8N5C6 (See protein sequence)
Recommended Name: S1 RNA-binding domain-containing protein 1  
Size: 995 amino acids; 111776 Da
Sequence caution: Sequence=AAY14821.1; Type=Erroneous gene model prediction;
Secondary accessions: Q53T56 Q96TA4 Q9NW11
Alternative splicing: 2 isoforms:  Q8N5C6-1   Q8N5C6-2   

Explore the universe of human proteins at neXtProt for SRBD1: NX_Q8N5C6

Explore proteomics data for SRBD1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SRBD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060549.4  
    ENSEMBL proteins: 
     ENSP00000263736   ENSP00000441272  

    SRBD1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SRBD1
    GenScript Custom Purified and Recombinant Proteins Services for SRBD1
    Novus Biologicals SRBD1 Protein
    Novus Biologicals SRBD1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SRBD1

     
    Search eBioscience for Proteins for SRBD1 

     
    antibodies-online proteins for SRBD1 

     
    antibodies-online peptides for SRBD1

    SRBD1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SRBD1
    Novus Biologicals SRBD1 Antibodies
    Abcam antibodies for SRBD1
    Cloud-Clone Corp. Antibodies for SRBD1
    ThermoFisher Antibodies for SRBD1
    LSBio Antibodies in human, mouse, rat for SRBD1
    antibodies-online antibodies for SRBD1 (16 products) 

    SRBD1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SRBD1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SRBD1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SRBD1
    Cloud-Clone Corp. CLIAs for SRBD1
    Search eBioscience for ELISAs for SRBD1 
    antibodies-online kits for SRBD1 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    Selected InterPro protein domains (see all 10):
     IPR012340 NA-bd_OB-fold
     IPR003029 Rbsml_prot_S1_RNA-bd_dom
     IPR023323 Tex-like_dom
     IPR023319 Tex-like_HTH_dom
     IPR006641 YqgF/RNaseH-like_dom

    Graphical View of Domain Structure for InterPro Entry Q8N5C6

    ProtoNet protein and cluster: Q8N5C6

    1 Blocks protein domain: IPB003029 RNA binding S1

    UniProtKB/Swiss-Prot: SRBD1_HUMAN, Q8N5C6
    Similarity: Contains 1 S1 motif domain


    Find genes that share domains with SRBD1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0016788hydrolase activity, acting on ester bonds IEA--
         
    Find genes that share ontologies with SRBD1           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for SRBD1:
     Cell division defect  Increased G2M DNA content  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SRBD1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SRBD1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SRBD1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SRBD1

    miRNA
    Products:
        
    miRTarBase miRNAs that target SRBD1:
    hsa-mir-124-3p (MIRT023133)

    Block miRNA regulation of human, mouse, rat SRBD1 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate SRBD1:
    hsa-miR-3163 hsa-miR-3159 hsa-miR-592
    SwitchGear 3'UTR luciferase reporter plasmidSRBD1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SRBD1
    Predesigned siRNA for gene silencing in human, mouse, rat SRBD1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SRBD1

    Clone
    Products:
         
    OriGene clones in human, mouse for SRBD1 (see all 7)
    OriGene ORF clones in mouse, rat for SRBD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SRBD1 (NM_018079)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SRBD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRBD1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SRBD1
    Browse ESI BIO Cell Lines and PureStem Progenitors for SRBD1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRBD1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SRBD1
    Interactions:

        Search GeneGlobe Interaction Network for SRBD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SRBD1 (Q8N5C63 ENSP000002637364) via UniProtKB, MINT, STRING, and/or I2D (see all 41)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SART3Q150203, ENSP000002282844I2D: score=2 STRING: ENSP00000228284
    USP45Q70EL23, ENSP000003333764I2D: score=2 STRING: ENSP00000333376
    PRKAA1Q131313I2D: score=1 
    CUX1ENSP000002925354STRING: ENSP00000292535
    SSRP1ENSP000002784124STRING: ENSP00000278412
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006139nucleobase-containing compound metabolic process IEA--

    Find genes that share ontologies with SRBD1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SRBD1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SRBD1 gene: 
    NM_018079.4  

    Unigene Cluster for SRBD1:

    S1 RNA binding domain 1
    Hs.14229  [show with all ESTs]
    Unigene Representative Sequence: NM_018079
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263736(uc010yoc.2 uc002rus.3) ENST00000490133 ENST00000475073
    ENST00000493649 ENST00000461805 ENST00000535761
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SRBD1 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate SRBD1:
    hsa-miR-3163 hsa-miR-3159 hsa-miR-592
    SwitchGear 3'UTR luciferase reporter plasmidSRBD1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SRBD1
    Predesigned siRNA for gene silencing in human, mouse, rat SRBD1
    Clone
    Products:
         
    OriGene clones in human, mouse for SRBD1 (see all 7)
    OriGene ORF clones in mouse, rat for SRBD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SRBD1 (NM_018079)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SRBD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRBD1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SRBD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SRBD1
      QuantiTect SYBR Green Assays in human, mouse, rat SRBD1
      QuantiFast Probe-based Assays in human, mouse, rat SRBD1

    Additional mRNA sequence: 

    AK001241.1 AK055896.1 AK056536.1 AK301122.1 AK316222.1 BC032538.1 

    5 DOTS entries:

    DT.452509  DT.100718784  DT.95355916  DT.95250943  DT.99993307 

    Selected AceView cDNA sequences (see all 92):

    BM969133 AI880589 AK056536 BQ434016 BQ427891 BX369047 BF059599 BM449711 
    CA426893 AL529203 AI283963 BM127324 NM_018079 AI655126 AA173044 BE671767 
    CK906214 CA310423 BX099167 CN482331 AK055896 AU124317 CB240838 CR615345 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SRBD1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
    SP1:                                                                                                        -                                 
    SP2:                                                                                                                                          
    SP3:                                                                                                                                          


    ECgene alternative splicing isoforms for SRBD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SRBD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAGCCAAAA
    SRBD1 Expression
    About this image


    SRBD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebellum
     
     Ovary (Reproductive System)
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    SRBD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SRBD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.14229
        Custom PCR Arrays for SRBD1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SRBD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SRBD1
    QuantiTect SYBR Green Assays in human, mouse, rat SRBD1
    QuantiFast Probe-based Assays in human, mouse, rat SRBD1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRBD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for SRBD1 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Srbd11 , 5 S1 RNA binding domain 11, 5 83.28(n)1
    83.08(a)1
      17 (56.51 cM)5
    785861  NM_030133.31  NP_084409.31 
     859846655 
    chicken
    (Gallus gallus)
    Aves SRBD11 S1 RNA binding domain 1 71.08(n)
    71.36(a)
      421408  XM_419463.3  XP_419463.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    76(a)
    62(a)
    many → 1
    many → 1
    GL343284.1(935912-959297)
    GL343284.1(738555-790547)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480463772   -- 72.2(n)    48046377 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5582011 uncharacterized LOC558201 61.53(n)
    61.43(a)
      558201  XM_001921482.4  XP_001921517.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG311561 CG31156 46.46(n)
    38.48(a)
      42669  NM_142813.6  NP_651070.3 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK973.11 ZK973.1 47.22(n)
    35.22(a)
      172040  NM_058961.3  NP_491362.1 


    ENSEMBL Gene Tree for SRBD1 (if available)
    TreeFam Gene Tree for SRBD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SRBD1 (see all 4905)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1422393281,2
    --45615537(+) CCATCC/TCCACT 1 -- int10--------
    rs1445400571,2
    --45615602(+) TCACAC/TCTGAT 1 -- int10--------
    rs1478185051,2
    --45615690(+) TATGCC/TAAATC 1 -- int10--------
    rs1915196331,2
    --45615879(+) GTTTCA/GAGCCA 1 -- ut310--------
    rs1833031221,2
    --45615975(+) AATTAA/TGAATG 1 -- ut310--------
    rs67543531,2
    C,F,H--45616023(+) TGGAAG/CGATTA 1 -- ut31 ese310Minor allele frequency- C:0.02NS EA NA WA CSA 684
    rs1880381311,2
    --45616143(+) TGTTAC/TACAAA 1 -- ut310--------
    rs1921270831,2
    --45616300(+) CAGAAA/GAAAAA 1 -- ut310--------
    rs1152587821,2
    C,F--45616313(+) AAAGGA/CAAGTG 1 -- ut311Minor allele frequency- C:0.14WA 118
    rs1142792131,2
    C,F--45616345(+) TAAGTG/TAATTA 1 -- ut311Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for SRBD1 (45615819 - 45839304 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SRBD1 (see all 18):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2720009CNV Deletion23290073
    esv2590571CNV Deletion19546169
    esv2671965CNV Deletion23128226
    esv2659564CNV Deletion23128226
    esv2618979CNV Deletion19546169
    esv2720008CNV Deletion23290073
    esv269905CNV Insertion20981092
    nsv873995CNV Loss21882294
    esv22205CNV Loss19812545
    dgv4111n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SRBD1
    DNA2.0 Custom Variant and Variant Library Synthesis for SRBD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease from the University of Copenhagen DISEASES database for SRBD1:
    Glaucoma

    Find genes that share disorders with SRBD1           About GenesLikeMe

    Genetic Association Database (GAD): SRBD1
    Human Genome Epidemiology (HuGE) Navigator: SRBD1 (3 documents)

    Export disorders for SRBD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SRBD1 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with SRBD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility. (PubMed id 20363506)1, 4  ....Bahram S. (Ophthalmology 2010)
    3. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (Gut 2009)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (amp 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells. (PubMed id 21282530)1 Vandamme J.... Angrand P.O. (Mol. Cell. Proteomics 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 55133 HGNC: 25521 AceView: FLJ10379 Ensembl:ENSG00000068784 euGenes: HUgn55133
    ECgene: SRBD1 H-InvDB: SRBD1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SRBD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SRBD1 gene:
    Search GeneIP for patents involving SRBD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SRBD1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SRBD1  
     OriGene qSTAR qPCR primer pairs in human, mouse for SRBD1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SRBD1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SRBD1   OriGene Custom Protein Services for SRBD1  

     
     
     Block miRNA regulation of human, mouse, rat SRBD1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SRBD1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SRBD1 Predesigned siRNA for gene silencing in human, mouse, rat SRBD1
     QuantiFast Probe-based Assays in human, mouse, rat SRBD1 QuantiTect SYBR Green Assays in human, mouse, rat SRBD1
     Custom PCR Arrays for SRBD1 Search Chromatin IP Primers for SRBD1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SRBD1  Search GeneGlobe Interaction Network for SRBD1
     Regulatory tfbs in SRBD1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SRBD1 GenScript cDNA clones with any tag delivered in your preferred vector for SRBD1
     GenScript Custom Assay Services for SRBD1 GenScript Custom overexpressing Cell Line Services for SRBD1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SRBD1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SRBD1 antibodies
     SRBD1 proteins
     SRBD1 lysates
     Antibodies for SRBD1
     See all of Abcam's Antibodies, Kits and Proteins for SRBD1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SRBD1
     Antibodies for SRBD1
     ELISAs for SRBD1
     CLIAs for SRBD1



     Browse ESI BIO Cell Lines and PureStem Progenitors for SRBD1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRBD1
     SwitchGear 3'UTR luciferase reporter plasmids for SRBD1
     SwitchGear Promoter luciferase reporter plasmids for SRBD1
     ThermoFisher Antibodies for SRBD1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRBD1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SRBD1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SRBD1
     LSBio Antibodies in human, mouse, rat for SRBD1
     Browse compounds at ApexBio
     Search Addgene for plasmids for SRBD1
      Search eBioscience for proteins for SRBD1
      Search eBioscience for elisas for SRBD1
      eBioscience FlowRNA Probe Sets
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     antibodies-online antibodies for SRBD1 (16 products)
     antibodies-online kits for SRBD1 (4 products)
     antibodies-online peptides for SRBD1
     antibodies-online proteins for SRBD1
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SRBD1 gene at Home site.
    Version: 3.12.234 23 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4