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Aliases for SRBD1 Gene

Aliases for SRBD1 Gene

  • S1 RNA Binding Domain 1 2 3
  • S1 RNA-Binding Domain-Containing Protein 1 3
  • WUGSC:H_NH0576F01.1 3
  • H_NH0576F01.1 3

External Ids for SRBD1 Gene

Previous GeneCards Identifiers for SRBD1 Gene

  • GC02M045469
  • GC02M045615

Summaries for SRBD1 Gene

GeneCards Summary for SRBD1 Gene

SRBD1 (S1 RNA Binding Domain 1) is a Protein Coding gene. GO annotations related to this gene include RNA binding and hydrolase activity, acting on ester bonds.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SRBD1 Gene

Genomics for SRBD1 Gene

Regulatory Elements for SRBD1 Gene

Genomic Location for SRBD1 Gene

45,388,680 bp from pter
45,612,165 bp from pter
223,486 bases
Minus strand

Genomic View for SRBD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SRBD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SRBD1 Gene

Proteins for SRBD1 Gene

  • Protein details for SRBD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    S1 RNA-binding domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q53T56
    • Q96TA4
    • Q9NW11

    Protein attributes for SRBD1 Gene

    995 amino acids
    Molecular mass:
    111776 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAY14821.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for SRBD1 Gene


neXtProt entry for SRBD1 Gene

Proteomics data for SRBD1 Gene at MOPED

Post-translational modifications for SRBD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SRBD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SRBD1 Gene

Domains for SRBD1 Gene

Suggested Antigen Peptide Sequences for SRBD1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q8N5C6
  • Contains 1 S1 motif domain.
genes like me logo Genes that share domains with SRBD1: view

No data available for Gene Families for SRBD1 Gene

Function for SRBD1 Gene

Gene Ontology (GO) - Molecular Function for SRBD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding IEA --
GO:0016788 hydrolase activity, acting on ester bonds --
genes like me logo Genes that share ontologies with SRBD1: view

Phenotypes for SRBD1 Gene

genes like me logo Genes that share phenotypes with SRBD1: view

Animal Model Products

miRNA for SRBD1 Gene

miRTarBase miRNAs that target SRBD1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SRBD1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SRBD1 Gene

Localization for SRBD1 Gene

Subcellular locations from

Jensen Localization Image for SRBD1 Gene COMPARTMENTS Subcellular localization image for SRBD1 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SRBD1 Gene

Pathways for SRBD1 Gene

SuperPathways for SRBD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SRBD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006139 nucleobase-containing compound metabolic process IEA --
genes like me logo Genes that share ontologies with SRBD1: view

No data available for Pathways by source for SRBD1 Gene

Transcripts for SRBD1 Gene

Unigene Clusters for SRBD1 Gene

S1 RNA binding domain 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SRBD1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SRBD1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
SP1: -

Relevant External Links for SRBD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SRBD1 Gene

mRNA expression in normal human tissues for SRBD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for SRBD1 Gene

This gene is overexpressed in Lung (16.0), Plasma (14.4), and Adipocyte (10.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SRBD1 Gene

SOURCE GeneReport for Unigene cluster for SRBD1 Gene Hs.14229

genes like me logo Genes that share expressions with SRBD1: view

Expression partners for SRBD1 Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SRBD1 Gene

Orthologs for SRBD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SRBD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SRBD1 35
  • 89.27 (n)
  • 88.8 (a)
SRBD1 36
  • 89 (a)
(Canis familiaris)
Mammalia SRBD1 35
  • 91.57 (n)
  • 90.69 (a)
SRBD1 36
  • 90 (a)
(Mus musculus)
Mammalia Srbd1 35
  • 83.28 (n)
  • 83.08 (a)
Srbd1 16
Srbd1 36
  • 83 (a)
(Pan troglodytes)
Mammalia SRBD1 35
  • 99.23 (n)
  • 98.89 (a)
SRBD1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Srbd1 35
  • 83.62 (n)
  • 82.74 (a)
(Monodelphis domestica)
Mammalia SRBD1 36
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia SRBD1 36
  • 75 (a)
(Gallus gallus)
Aves SRBD1 35
  • 71.08 (n)
  • 71.36 (a)
SRBD1 36
  • 70 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 62 (a)
-- 36
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia srbd1 35
  • 66.53 (n)
  • 67.6 (a)
(Danio rerio)
Actinopterygii LOC558201 35
  • 61.53 (n)
  • 61.43 (a)
srbd1 36
  • 53 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG31156 35
  • 46.46 (n)
  • 38.48 (a)
CG31156 36
  • 33 (a)
(Caenorhabditis elegans)
Secernentea ZK973.1 35
  • 47.22 (n)
  • 35.22 (a)
ZK973.1 36
  • 29 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 45 (a)
Species with no ortholog for SRBD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SRBD1 Gene

Gene Tree for SRBD1 (if available)
Gene Tree for SRBD1 (if available)

Paralogs for SRBD1 Gene

No data available for Paralogs for SRBD1 Gene

Variants for SRBD1 Gene

Sequence variations from dbSNP and Humsavar for SRBD1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs713305 -- 45,573,728(-) GACAC(A/G)TCCTT intron-variant
rs713306 -- 45,573,564(+) AATCT(C/T)CCCAT intron-variant
rs714041 -- 45,436,906(-) ATCAC(G/T)TATTA intron-variant
rs714265 -- 45,476,509(-) TCAAG(A/G)CAGCA intron-variant
rs718325 -- 45,604,963(-) cccac(A/T)ggatg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SRBD1 Gene

Variant ID Type Subtype PubMed ID
esv2751894 CNV Gain 17911159
nsv833958 CNV Gain 17160897
esv2618979 CNV Deletion 19546169
esv2720008 CNV Deletion 23290073
esv2720009 CNV Deletion 23290073
esv269905 CNV Insertion 20981092
dgv217n21 CNV Loss 19592680
nsv457285 CNV Loss 19166990
esv2590571 CNV Deletion 19546169
dgv4111n71 CNV Loss 21882294
esv2671965 CNV Deletion 23128226
nsv873995 CNV Loss 21882294
nsv519046 CNV Loss 19592680
nsv521080 CNV Loss 19592680
nsv520955 CNV Loss 19592680
esv2659564 CNV Deletion 23128226
esv22205 CNV Loss 19812545
nsv457296 CNV Loss 19166990

Relevant External Links for SRBD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SRBD1 Gene

Disorders for SRBD1 Gene

(1) University of Copenhagen DISEASES for SRBD1 Gene

Relevant External Links for SRBD1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with SRBD1: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for SRBD1 Gene

Publications for SRBD1 Gene

  1. Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility. (PMID: 20363506) . … Bahram S. (Ophthalmology 2010) 3 48
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G. … Wijmenga C. (Gut 2009) 3 48
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for SRBD1 Gene

Sources for SRBD1 Gene

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