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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SQRDL Gene

protein-coding   GIFtS: 50
GCID: GC15P045927

sulfide quinone reductase-like (yeast)
 Explore 2 diseases affiliated with
SQRDL via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SQRDL    

Aliases
for SQRDL gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Sulfide Quinone Reductase-Like (Yeast)1 2
CGI-441
PRO19752
Sulfide Dehydrogenase Like2
Sulfide:Quinone Oxidoreductase, Mitochondrial2
EC 1.-.-.-3

External Ids:    HGNC: 203901   Entrez Gene: 584722   Ensembl: ENSG000001377677   UniProtKB: Q9Y6N53   

Export aliases for SQRDL gene to outside databases

Previous GC identifers: GC15P041484 GC15P038973 GC15P043459 GC15P043643 GC15P043617 GC15P043714 GC15P022749


Summaries
for SQRDL gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SQRDL:
The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides,
thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that
encode the same protein. (provided by RefSeq, Sep 2012)

UniProtKB/Swiss-Prot: SQRD_HUMAN, Q9Y6N5
Function: Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone (By similarity)




Genomic Views
for SQRDL gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SQRDL gene promoter:
         GR   STAT1   ISGF-3   NCX/Ncx   FOXO3   POU6F1 (c2)   FOXO3b   FOXO3a   Cart-1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SQRDL promoter sequence
   Search SABiosciences Chromatin IP Primers for SQRDL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SQRDL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15   Ensembl cytogenetic band:  15q21.1   HGNC cytogenetic band: 15q21.1

SQRDL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SQRDL gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P045927:  view genomic region     (about GC identifiers)

Start:
 45,923,346 bp from pter      End:
 45,983,492 bp from pter
Size:
 60,147 bases      Orientation:
 plus strand

Proteins
for SQRDL gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SQRD_HUMAN, Q9Y6N5 (See protein sequence)
Recommended Name: Sulfide:quinone oxidoreductase, mitochondrial precursor  
Size: 450 amino acids; 49961 Da
Cofactor: Binds 1 FAD per subunit (By similarity)
Subcellular location: Mitochondrion (Probable)
Secondary accessions: Q9UQM8

Explore the universe of human proteins at neXtProt for SQRDL: NX_Q9Y6N5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y6N5

    • SQRDL Protein expression data from MOPED and PaxDb:    About this image 
    SQRDL Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001258142.1  NP_067022.1  

    ENSEMBL proteins: 
     ENSP00000456019   ENSP00000457592   ENSP00000456979   ENSP00000456075   ENSP00000260324  
     ENSP00000457937   ENSP00000454520   ENSP00000454953  
    Reactome Protein details: Q9Y6N5
    Human Recombinant Protein Products for SQRDL: 
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    Novus Biologicals SQRDL Protein
    Novus Biologicals SQRDL Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SQRDL

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005743mitochondrial inner membrane TAS--

    SQRDL for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SQRDL

    Protein Domains /
    Families
    for SQRDL gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SQRDL for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR015904 Sulphide_quinone_reductase
     IPR023753 Pyr_nucl-diS_OxRdtase_FAD/NAD

    Graphical View of Domain Structure for InterPro Entry Q9Y6N5

    ProtoNet protein and cluster: Q9Y6N5

    UniProtKB/Swiss-Prot: SQRD_HUMAN, Q9Y6N5
    Similarity: Belongs to the SQRD family


    Function
    for SQRDL gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SQRD_HUMAN, Q9Y6N5
    Function: Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone (By similarity)

         Enzyme Number (IUBMB): EC 1.-.-.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016491oxidoreductase activity ----
    GO:0070224sulfide:quinone oxidoreductase activity TAS--
         
    SQRDL for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for SQRDL:
     G0/1 arrest  Increased G1 DNA content  Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SQRDL 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SQRDL
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    SwitchGear 3'UTR luciferase reporter plasmid: SQRDL 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SQRDL (see all 7)
    OriGene shRNA RFP: SQRDL
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for SQRDL gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Degradation of cysteine and homocysteine
    		Degradation of cysteine and homocysteine1.00
    		Sulfide oxidation to sulfate0.62
    2Metabolism of amino acids and derivatives
    		Metabolism of amino acids and derivatives1.00
    3Sulfur amino acid metabolism
    		Sulfur amino acid metabolism1.00
    4Metabolism
    		Metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5        Reactome Pathways for SQRDL
        Sulfide oxidation to sulfate
    Metabolism
    Sulfur amino acid metabolism
    Degradation of cysteine and homocysteine
    Metabolism of amino acids and derivatives



    SQRDL for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SQRDL

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/10 Interacting proteins for SQRDL (Q9Y6N53 ENSP000002603244) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=4 STRING: ENSP00000367207
    SMAD2Q157963, ENSP000002621604I2D: score=2 STRING: ENSP00000262160
    SMAD3P840223, ENSP000003329734I2D: score=2 STRING: ENSP00000332973
    CFTRP135693I2D: score=1 
    ETHE1ENSP000002921474STRING: ENSP00000292147
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000096sulfur amino acid metabolic process TAS--
    GO:0000098sulfur amino acid catabolic process TAS--
    GO:0034641cellular nitrogen compound metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--
    GO:0070221sulfide oxidation, using sulfide:quinone oxidoreductase TAS--

    SQRDL for ontologies           About GeneDecksing



    Drugs & Compounds
    for SQRDL gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SQRDL

    1 HMDB Compound for SQRDL    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    Search CenterWatch for drugs/clinical trials and news about SQRDL / SQRD 

    Transcripts
    for SQRDL gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SQRDL gene (2 alternative transcripts): 
    NM_001271213.1  NM_021199.3  

    Unigene Cluster for SQRDL:

    Sulfide quinone reductase-like (yeast)
    Hs.511251  [show with all ESTs]
    Unigene Representative Sequence: NM_021199
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000568606(uc001zvu.3) ENST00000565227 ENST00000563296 ENST00000561735
    ENST00000260324(uc001zvv.3) ENST00000561493 ENST00000566934 ENST00000565997


    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SQRDL (see all 7)
    OriGene shRNA RFP: SQRDL
    OriGene siRNA: SQRDL
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    Sirion Biotech Custom design and validation of potent shRNA sequences against SQRDL 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SQRDL (see all 2)
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    GenScript: all cDNA clones in your preferred vector: SQRDL (NM_021199)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SQRDL
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    Additional cDNA sequence: 

    AF042284.1 AF118085.1 AF151802.1 AK130140.1 AK222463.1 AK313111.1 BC016836.1 

    18 DOTS entries:

    DT.95144168  DT.217197  DT.97766447  DT.100029960  DT.100824435  DT.121035048  DT.95144098  DT.100824443 
    DT.217196  DT.92443218  DT.97848027  DT.121035014  DT.100824432  DT.121035011  DT.121035027  DT.95293840 
    DT.97770125  DT.95174153 

    24/663 AceView cDNA sequences (see all 663):

    BM311282 CD679330 AV659324 AI133370 BU164937 CA306091 BM991915 CB122026 
    AI275561 CA423256 CR613954 AW768946 CA307620 AF080470 BM980065 BC016836 
    AW182738 AA664347 AA643646 AA486172 BQ939887 BU608879 AI095921 W61293 

    GeneLoc Exon Structure


    Expression
    for SQRDL gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SQRDL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATGGGCTTGA
    SQRDL Expression
    About this image

    SQRDL expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    Fetal cardiomyocytes (20 weeks) (Primary Cell)Heart, Myocardium
    CD31, CD144 positive cells (Two-step protocol fo...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SQRDL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SQRDL

    SOURCE GeneReport for Unigene cluster: Hs.511251
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    In Situ
    Assay Products:     
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    Orthologs
    for SQRDL gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for SQRDL gene from 7/28 species (see all 28)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Sqrdl1 , 5 sulfide quinone reductase-like (yeast)1, 5 83.11(n)1
    86.89(a)1    		   2 (60.67 cM)5
    590101  NM_001162503.11  NP_001155975.11 
     1227652375 
    chicken
    (Gallus gallus)    		 Aves SQRDL1 sulfide quinone reductase-like (yeast) 74.01(n)
    80.05(a)    		   415445  XM_413825.3  XP_413825.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SQRDL6
    		 --
    		 79(a)
    		 1 → many
    		 GL343747.1(208461-217000)
    African clawed frog
    (Xenopus laevis)    		 Amphibia sqrdl-prov2 sulfide quinone reductase-like (yeast) 75.77(n)    BC056037.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufj81h042 Transcribed sequence with weak similarity to protein more 77.2(n)    BI881367.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG149971 , 3 CG149971 51(a)3
    57.09(n)1
    51.93(a)1    		   64A123
    385141  NM_139620.11  NP_647877.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea Y9C9A.163
    sqrd-11    		 Protein SQRD-11 43(a)
    (best of 2)3
    52.23(n)1
    46.04(a)1    		   IV(4974393-4976509)3
    1783741  NM_070328.51  NP_502729.11 


    ENSEMBL Gene Tree for SQRDL (if available)
    TreeFam Gene Tree for SQRDL (if available) 

    Paralogs
    for SQRDL gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SQRDL gene
    ENSG000002601702  

    SQRDL for paralogs           About GeneDecksing



    Genomic Variants
    for SQRDL gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1167 NCBI SNPs in SQRDL are shown (see all 1167)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 15 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs6082581,2
    		--45921460(-) gagacC/Tagcct 1 -- us2k10--------
    rs1431221381,2
    		--45921484(+) CAAGCA/GATACA 1 -- us2k10--------
    rs64931621,2
    		C,F,A,H--45921561(+) TTTAAC/TGATGA 1 -- us2k111Minor allele frequency- T:0.12NS EA NA CSA WA 1200
    rs129098451,2
    		H--45921652(+) TTTTCT/GTATGT 1 -- us2k14Minor allele frequency- G:0.00NS EA 420
    rs129086831,2
    		H--45921659(+) ATGTCC/TTAGGA 1 -- us2k14Minor allele frequency- T:0.00NS EA 420
    rs129086961,2
    		H--45921667(+) GGAGAC/ACTTTC 1 -- us2k14Minor allele frequency- A:0.00NS EA 420
    rs129098501,2
    		H--45921669(+) AGACCT/ATTCTG 1 -- us2k14Minor allele frequency- A:0.00NS EA 420
    rs1512029261,2
    		--45921707(+) ACCCCG/TCCCTG 1 -- us2k10--------
    rs1832829271,2
    		--45921822(+) TGCCCC/TGGCTG 1 -- us2k10--------
    rs1885981531,2
    		--45921834(+) AGTGCA/TGTGGC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SQRDL (45923346 - 45983492 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for SQRDL
         1 Indel: 66791

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SQRDL
    DNA2.0 Custom Variant and Variant Library Synthesis for SQRDL

    Disorders / Diseases
    for SQRDL gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SQRDL for disorders           About GeneDecksing

    2 diseases for SQRDL:    About MalaCards
    tuberculosis    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: SQRDL (1 document)

    Export disorders for SQRDL gene to outside databases

    Publications
    for SQRDL gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SQRDL gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with SQRDL)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    2. A fission yeast gene for mitochondrial sulfide oxidation. (PubMed id 10224084)1, 2, 3 Vande Weghe J.G. and Ow D.W. (1999)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Human sulfide:quinone oxidoreductase catalyzes the fir st step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite. (PubMed id 22852582)1 Jackson M.R....Jorns M.S. (2012)
    7. Proteomics reveals that redox regulation is disrupted in patients with ethylmalonic encephalopathy. (PubMed id 21410200)1 Palmfeldt J....Gregersen N. (2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
    10. Oxidation of hydrogen sulfide remains a priority in ma mmalian cells and causes reverse electron transfer in colonocytes. (PubMed id 20398623)1 Lagoutte E....Bouillaud F. (2010)

    External Searches for SQRDL gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing SQRDL gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 58472 HGNC: 20390 AceView: PLDNandSQRDL Ensembl:ENSG00000137767 euGenes: HUgn58472
    ECgene: SQRDL H-InvDB: SQRDL

    Other Databases showing SQRDL gene

    (According to HUGE)
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    Specialized Databases showing SQRDL gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SQRDL Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SQRDL gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SQRDL gene:
    Search GeneIP for patents involving SQRDL

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