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SQRDL Gene

protein-coding   GIFtS: 53
GCID: GC15P045927

Sulfide Quinone Reductase-Like (Yeast)

  See SQRDL-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sulfide Quinone Reductase-Like (Yeast)1 2
PRO19752
Sulfide Dehydrogenase Like2
Sulfide:Quinone Oxidoreductase, Mitochondrial2
EC 1.-.-.-3

External Ids:    HGNC: 203901   Entrez Gene: 584722   Ensembl: ENSG000001377677   UniProtKB: Q9Y6N53   

Export aliases for SQRDL gene to outside databases

Previous GC identifers: GC15P041484 GC15P038973 GC15P043459 GC15P043643 GC15P043617 GC15P043714 GC15P022749


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SQRDL Gene:
The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to
persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple
transcript variants that encode the same protein. (provided by RefSeq, Sep 2012)

GeneCards Summary for SQRDL Gene:
SQRDL (sulfide quinone reductase-like (yeast)) is a protein-coding gene. Diseases associated with SQRDL include ethylmalonic encephalopathy. GO annotations related to this gene include sulfide:quinone oxidoreductase activity. An important paralog of this gene is ENSG00000260170.

UniProtKB/Swiss-Prot: SQRD_HUMAN, Q9Y6N5
Function: Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NC_018926.2  NT_010194.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the SQRDL gene promoter:
         GR   STAT1   ISGF-3   NCX/Ncx   FOXO3   POU6F1 (c2)   FOXO3b   FOXO3a   Cart-1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSQRDL promoter sequence
   Search Chromatin IP Primers for SQRDL

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SQRDL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15   Ensembl cytogenetic band:  15q21.1   HGNC cytogenetic band: 15q21.1

SQRDL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SQRDL gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P045927:  view genomic region     (about GC identifiers)

Start:
45,923,346 bp from pter      End:
45,983,492 bp from pter
Size:
60,147 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SQRD_HUMAN, Q9Y6N5 (See protein sequence)
Recommended Name: Sulfide:quinone oxidoreductase, mitochondrial precursor  
Size: 450 amino acids; 49961 Da
Cofactor: Binds 1 FAD per subunit (By similarity)
Secondary accessions: Q9UQM8

Explore the universe of human proteins at neXtProt for SQRDL: NX_Q9Y6N5

Explore proteomics data for SQRDL at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SQRDL Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001258142.1  NP_067022.1  

    ENSEMBL proteins: 
     ENSP00000456019   ENSP00000457592   ENSP00000456979   ENSP00000456075   ENSP00000260324  
     ENSP00000457937   ENSP00000454520   ENSP00000454953  
    Reactome Protein details: Q9Y6N5

    SQRDL Human Recombinant Protein Products:

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    antibodies-online proteins for SQRDL (2 products) 

     
    antibodies-online peptides for SQRDL

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    antibodies-online antibodies for SQRDL (17 products) 

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    antibodies-online kits for SQRDL (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR015904 Sulphide_quinone_reductase
     IPR023753 Pyr_nucl-diS_OxRdtase_FAD/NAD

    Graphical View of Domain Structure for InterPro Entry Q9Y6N5

    ProtoNet protein and cluster: Q9Y6N5

    UniProtKB/Swiss-Prot: SQRD_HUMAN, Q9Y6N5
    Similarity: Belongs to the SQRD family


    Find genes that share domains with SQRDL           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SQRD_HUMAN, Q9Y6N5
    Function: Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone (By similarity)

         Enzyme Number (IUBMB): EC 1.-.-.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016491oxidoreductase activity ----
    GO:0070224sulfide:quinone oxidoreductase activity TAS--
         
    Find genes that share ontologies with SQRDL           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for SQRDL:
     G0/1 arrest  Increased G1 DNA content  Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for SQRDL

    miRNA
    Products:
        
    miRTarBase miRNAs that target SQRDL:
    hsa-mir-124-3p (MIRT022400)

    Block miRNA regulation of human, mouse, rat SQRDL using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SQRDL
    SwitchGear 3'UTR luciferase reporter plasmidSQRDL 3' UTR sequence
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    Predesigned siRNA for gene silencing in human, mouse, rat SQRDL

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SQRD_HUMAN, Q9Y6N5: Mitochondrion (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion4
    cytosol3
    endoplasmic reticulum1
    lysosome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005743mitochondrial inner membrane TAS--

    Find genes that share ontologies with SQRDL           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SQRDL About    
    See pathways by source

    SuperPathContained pathways About
    1Sulfur amino acid metabolism
    Sulfur amino acid metabolism0.35
    Sulfide oxidation to sulfate0.00
    Degradation of cysteine and homocysteine0.00
    2Metabolism
    Metabolism0.38
    3Sulfur metabolism
    Sulfur metabolism
    4Metabolism of amino acids and derivatives
    Metabolism of amino acids and derivatives


    Find genes that share SuperPaths with SQRDL           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SQRDL
        Sulfide oxidation to sulfate


    1 Kegg Pathway  (Kegg details for SQRDL):
        Sulfur metabolism

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SQRDL
    Interactions:

        Search GeneGlobe Interaction Network for SQRDL

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for SQRDL (Q9Y6N53 ENSP000002603244) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=4 STRING: ENSP00000367207
    SMAD2Q157963, ENSP000002621604I2D: score=2 STRING: ENSP00000262160
    SMAD3P840223, ENSP000003329734I2D: score=2 STRING: ENSP00000332973
    CFTRP135693I2D: score=1 
    ETHE1ENSP000002921474STRING: ENSP00000292147
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000096sulfur amino acid metabolic process TAS--
    GO:0000098sulfur amino acid catabolic process TAS--
    GO:0034641cellular nitrogen compound metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--
    GO:0055114oxidation-reduction process ----

    Find genes that share ontologies with SQRDL           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SQRDL (SQRD)

    1 HMDB Compound for SQRDL    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SQRDL gene (2 alternative transcripts): 
    NM_001271213.1  NM_021199.3  

    Unigene Cluster for SQRDL:

    Sulfide quinone reductase-like (yeast)
    Hs.511251  [show with all ESTs]
    Unigene Representative Sequence: NM_021199
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000568606(uc001zvu.3) ENST00000565227 ENST00000563296 ENST00000561735
    ENST00000260324(uc001zvv.3) ENST00000561493 ENST00000566934 ENST00000565997

    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat SQRDL
      QuantiFast Probe-based Assays in human, mouse, rat SQRDL

    Additional mRNA sequence: 

    AF042284.1 AF118085.1 AF151802.1 AK130140.1 AK222463.1 AK313111.1 BC016836.1 

    18 DOTS entries:

    DT.95144168  DT.217197  DT.97766447  DT.100029960  DT.100824435  DT.121035048  DT.95144098  DT.100824443 
    DT.217196  DT.92443218  DT.97848027  DT.121035014  DT.100824432  DT.121035011  DT.121035027  DT.95293840 
    DT.97770125  DT.95174153 

    Selected AceView cDNA sequences (see all 663):

    BI906763 AK128626 BU753504 BU949080 CD368153 CA306091 AI819151 BM821029 
    BU164937 AI133370 AA777545 CA432921 CD679330 BM311282 CA943577 AA468902 
    BU542066 BQ709939 AL041648 CB123052 BU676976 AI475380 BM707938 BM988907 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SQRDL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGGGCTTGA
    SQRDL Expression
    About this image


    SQRDL expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Human umbilical vein endothelial cells (HUVEC)
             Endothelial-like cells
     
     Liver (Hepatobiliary System)    fully expand to see all 2 entries
             Hepatocytes Liver Lobule
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     NULL (Uncategorized)
             CD31, CD144 positive cells
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
    SQRDL Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SQRDL Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.511251
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SQRDL gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sqrdl1 , 5 sulfide quinone reductase-like (yeast)1, 5 83.11(n)1
    86.89(a)1
      2 (60.67 cM)5
    590101  NM_001162503.11  NP_001155975.11 
     1227652375 
    chicken
    (Gallus gallus)
    Aves SQRDL1 sulfide quinone reductase-like (yeast) 73.96(n)
    79.95(a)
      415445  XM_004943810.1  XP_004943867.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    78(a)
    1 → many
    GL343747.1(208461-217692)
    African clawed frog
    (Xenopus laevis)
    Amphibia sqrdl-prov2 sulfide quinone reductase-like (yeast) 75.77(n)    BC056037.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj81h042 Transcribed sequence with weak similarity to protein more 77.2(n)    BI881367.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG149971 , 3 CG149971 51(a)3
    56.97(n)1
    51.68(a)1
      64A123
    385141  NM_139620.21  NP_647877.11 
    worm
    (Caenorhabditis elegans)
    Secernentea Y9C9A.163
    sqrd-11
    sqrd-11 43(a)
    (best of 2)3
    52.23(n)1
    46.04(a)1
      IV(4974393-4976509)3
    1783741  NM_001268869.11  NP_001255798.11 


    ENSEMBL Gene Tree for SQRDL (if available)
    TreeFam Gene Tree for SQRDL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SQRDL gene
    ENSG000002601702  

    Find genes that share paralogs with SQRDL           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SQRDL (see all 1351)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs6082581,2
    C--45921460(-) gagacC/Tagcct 1 -- us2k10--------
    rs1431221381,2
    --45921484(+) CAAGCA/GATACA 1 -- us2k10--------
    rs64931621,2
    C,F,A,H--45921561(+) TTTAAC/TGATGA 1 -- us2k111Minor allele frequency- T:0.12NS EA NA CSA WA 1200
    rs129098451,2
    H--45921652(+) TTTTCT/GTATGT 1 -- us2k14Minor allele frequency- G:0.00NS EA 420
    rs129086831,2
    H--45921659(+) ATGTCC/TTAGGA 1 -- us2k14Minor allele frequency- T:0.00NS EA 420
    rs129086961,2
    H--45921667(+) GGAGAC/ACTTTC 1 -- us2k14Minor allele frequency- A:0.00NS EA 420
    rs129098501,2
    H--45921669(+) AGACCT/ATTCTG 1 -- us2k14Minor allele frequency- A:0.00NS EA 420
    rs1512029261,2
    C--45921707(+) ACCCCG/TCCCTG 1 -- us2k10--------
    rs1832829271,2
    --45921822(+) TGCCCC/TGGCTG 1 -- us2k10--------
    rs1885981531,2
    --45921834(+) AGTGCA/TGTGGC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SQRDL (45923346 - 45983492 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SQRDL:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv23356CNV Gain19812545
    nsv904188CNV Gain21882294
    nsv526945CNV Gain19592680
    dgv2379n71CNV Gain21882294
    nsv904190CNV Gain21882294
    esv274920CNV Complex21479260

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for SQRDL:    
    About MalaCards
    ethylmalonic encephalopathy


    Find genes that share disorders with SQRDL           About GenesLikeMe

    Genetic Association Database (GAD): SQRDL
    Human Genome Epidemiology (HuGE) Navigator: SQRDL (1 document)

    Export disorders for SQRDL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SQRDL gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with SQRDL)
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    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    2. A fission yeast gene for mitochondrial sulfide oxidation. (PubMed id 10224084)1, 2, 3 Vande Weghe J.G. and Ow D.W. (J. Biol. Chem. 1999)
    3. Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. (PubMed id 20966902)1, 4 Croteau-Chonka D.C....Mohlke K.L. (Obesity (Silver Spring) 2011)
    4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Proteomic analysis of the NOS2 interactome in human airway epithelial cells. (PubMed id 23438482)1 Foster M.W....Marshall H.E. (Nitric Oxide 2013)
    7. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. PKCI/ promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria. (PubMed id 22304920)1 Lau E....Ronai Z.A. (Cell 2012)
    10. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 58472 HGNC: 20390 AceView: PLDNandSQRDL Ensembl:ENSG00000137767 euGenes: HUgn58472
    ECgene: SQRDL Kegg: 58472 H-InvDB: SQRDL

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SQRDL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SQRDL gene:
    Search GeneIP for patents involving SQRDL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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