Aliases for SQRDL Gene
External Ids for SQRDL Gene
Previous GeneCards Identifiers for SQRDL Gene
The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]
GeneCards Summary for SQRDL Gene
SQRDL (Sulfide Quinone Reductase-Like (Yeast)) is a Protein Coding gene. Diseases associated with SQRDL include Ethylmalonic Encephalopathy. Among its related pathways are Sulfur amino acid metabolism and Sulfur metabolism. GO annotations related to this gene include oxidoreductase activity and sulfide:quinone oxidoreductase activity. An important paralog of this gene is ENSG00000260170.
UniProtKB/Swiss-Prot for SQRDL Gene
Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro).