Aliases for SPZ1 Gene
External Ids for SPZ1 Gene
Previous GeneCards Identifiers for SPZ1 Gene
This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011]
GeneCards Summary for SPZ1 Gene
SPZ1 (Spermatogenic Leucine Zipper 1) is a Protein Coding gene. Among its related pathways are p53 Signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding.
UniProtKB/Swiss-Prot for SPZ1 Gene
Transcription factor that binds to the DNA sequence 5-CANNTG-3(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis (By similarity).