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Aliases for SPTY2D1 Gene

Aliases for SPTY2D1 Gene

  • SPT2, Suppressor Of Ty, Domain Containing 1 (S. Cerevisiae) 2 3
  • SPT2 Domain-Containing Protein 1 4
  • Protein KU002155 4

External Ids for SPTY2D1 Gene

Previous GeneCards Identifiers for SPTY2D1 Gene

  • GC11M018585
  • GC11M018312

Summaries for SPTY2D1 Gene

GeneCards Summary for SPTY2D1 Gene

SPTY2D1 (SPT2, Suppressor Of Ty, Domain Containing 1 (S. Cerevisiae)) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPTY2D1 Gene

Genomics for SPTY2D1 Gene

Regulatory Elements for SPTY2D1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SPTY2D1 Gene

18,606,401 bp from pter
18,634,791 bp from pter
28,391 bases
Minus strand

Genomic View for SPTY2D1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPTY2D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPTY2D1 Gene

Proteins for SPTY2D1 Gene

  • Protein details for SPTY2D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein SPT2 homolog
    Protein Accession:
    Secondary Accessions:
    • Q6AWA5
    • Q6MZI5
    • Q7Z390
    • Q7Z470
    • Q86VG8
    • Q8N3E7
    • Q8N417
    • Q8N8I3

    Protein attributes for SPTY2D1 Gene

    685 amino acids
    Molecular mass:
    75599 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAP13351.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for SPTY2D1 Gene


neXtProt entry for SPTY2D1 Gene

Proteomics data for SPTY2D1 Gene at MOPED

Post-translational modifications for SPTY2D1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPTY2D1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPTY2D1 Gene

Domains for SPTY2D1 Gene

Protein Domains for SPTY2D1 Gene


Suggested Antigen Peptide Sequences for SPTY2D1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q68D10
  • Belongs to the SPT2 family.
genes like me logo Genes that share domains with SPTY2D1: view

No data available for Gene Families for SPTY2D1 Gene

Function for SPTY2D1 Gene

Gene Ontology (GO) - Molecular Function for SPTY2D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with SPTY2D1: view

Phenotypes for SPTY2D1 Gene

GenomeRNAi human phenotypes for SPTY2D1:
genes like me logo Genes that share phenotypes with SPTY2D1: view

Animal Model Products

CRISPR Products

miRNA for SPTY2D1 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPTY2D1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SPTY2D1 Gene

Localization for SPTY2D1 Gene

Subcellular locations from

Jensen Localization Image for SPTY2D1 Gene COMPARTMENTS Subcellular localization image for SPTY2D1 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for SPTY2D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with SPTY2D1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SPTY2D1 Gene

Pathways for SPTY2D1 Gene

SuperPathways for SPTY2D1 Gene

No Data Available

Interacting Proteins for SPTY2D1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000337991 Q68D10-SPT2_HUMAN for SPTY2D1 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for SPTY2D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with SPTY2D1: view

No data available for Pathways by source for SPTY2D1 Gene

Transcripts for SPTY2D1 Gene

mRNA/cDNA for SPTY2D1 Gene

Unigene Clusters for SPTY2D1 Gene

SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPTY2D1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPTY2D1 Gene

No ASD Table

Relevant External Links for SPTY2D1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPTY2D1 Gene

mRNA expression in normal human tissues for SPTY2D1 Gene

Protein differential expression in normal tissues for SPTY2D1 Gene

This gene is overexpressed in Heart (28.3), CD8 Tcells (25.6), and Fetal Liver (9.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SPTY2D1 Gene

SOURCE GeneReport for Unigene cluster for SPTY2D1 Gene Hs.745113

genes like me logo Genes that share expressions with SPTY2D1: view

Expression partners for SPTY2D1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SPTY2D1 Gene

Orthologs for SPTY2D1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SPTY2D1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPTY2D1 35
  • 87.42 (n)
  • 84.09 (a)
SPTY2D1 36
  • 84 (a)
(Canis familiaris)
Mammalia SPTY2D1 35
  • 89.38 (n)
  • 86.28 (a)
SPTY2D1 36
  • 83 (a)
(Mus musculus)
Mammalia Spty2d1 35
  • 84.39 (n)
  • 80.61 (a)
Spty2d1 16
Spty2d1 36
  • 80 (a)
(Pan troglodytes)
Mammalia SPTY2D1 35
  • 99.15 (n)
  • 98.94 (a)
SPTY2D1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC100365259 35
  • 84.27 (n)
  • 82.25 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 62 (a)
-- 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia SPTY2D1 36
  • 55 (a)
(Gallus gallus)
Aves SPTY2D1 35
  • 61.31 (n)
  • 58.66 (a)
SPTY2D1 36
  • 54 (a)
(Anolis carolinensis)
Reptilia SPTY2D1 36
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.10782 35
(Danio rerio)
Actinopterygii wufb01d08 35
spty2d1 36
  • 43 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5815 36
  • 28 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7207 36
  • 35 (a)
Species with no ortholog for SPTY2D1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SPTY2D1 Gene

Gene Tree for SPTY2D1 (if available)
Gene Tree for SPTY2D1 (if available)

Paralogs for SPTY2D1 Gene

No data available for Paralogs for SPTY2D1 Gene

Variants for SPTY2D1 Gene

Sequence variations from dbSNP and Humsavar for SPTY2D1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs872872 -- 18,634,884(+) CATGC(C/T)GTGCG upstream-variant-2KB
rs872873 -- 18,635,067(+) TGAAC(A/G)TATGC upstream-variant-2KB
rs1900329 -- 18,628,251(-) CAAAA(G/T)GGAGA intron-variant
rs2084220 -- 18,635,385(-) CCACC(A/G)CGCTC upstream-variant-2KB
rs2166519 -- 18,628,846(-) TAGTT(A/G)CATTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPTY2D1 Gene

Variant ID Type Subtype PubMed ID
nsv516413 CNV Loss 19592680

Relevant External Links for SPTY2D1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPTY2D1 Gene

Disorders for SPTY2D1 Gene

Relevant External Links for SPTY2D1

Genetic Association Database (GAD)

No disorders were found for SPTY2D1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SPTY2D1 Gene

Publications for SPTY2D1 Gene

  1. Biological, clinical and population relevance of 95 loci for blood lipids. (PMID: 20686565) Teslovich T.M. … Kathiresan S. (Nature 2010) 3 48
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Large-scale analysis of the human ubiquitin-related proteome. (PMID: 16196087) Matsumoto M. … Nakayama K.I. (Proteomics 2005) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for SPTY2D1 Gene

Sources for SPTY2D1 Gene

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