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SPTSSA Gene

protein-coding   GIFtS: 37
GCID: GC14M034902

Serine Palmitoyltransferase, Small Subunit A

(Previous name: chromosome 14 open reading frame 147)
(Previous symbol: C14orf147)
  Search for SPTSSA
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Serine Palmitoyltransferase, Small Subunit A1 2     Chromosome 14 Open Reading Frame 1471
C14orf1471 2 3 5     Serine Palmitoyltransferase Small Subunit A2
Small Subunit Of Serine Palmitoyltransferase A1 2 3     ssSPTa3
SSSPTA2 3 5     

External Ids:    HGNC: 203611   Entrez Gene: 1715462   Ensembl: ENSG000001653897   OMIM: 6135405   UniProtKB: Q969W03   

Export aliases for SPTSSA gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SPTSSA Gene:
Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in
sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA
preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM
611120) (Han et al., 2009 (PubMed 19416851)).(supplied by OMIM, Nov 2010)

GeneCards Summary for SPTSSA Gene:
SPTSSA (serine palmitoyltransferase, small subunit A) is a protein-coding gene. GO annotations related to this gene include serine C-palmitoyltransferase activity. An important paralog of this gene is SPTSSB.

UniProtKB/Swiss-Prot: SPTSA_HUMAN, Q969W0
Function: Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine
palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a
strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as
substrates, with a slight preference for C14-CoA




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for SPTSSA
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSPTSSA promoter sequence
   Search Chromatin IP Primers for SPTSSA

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPTSSA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q13.1   Ensembl cytogenetic band:  14q13.1   HGNC cytogenetic band: 14q13.1

SPTSSA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPTSSA gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M034902:  view genomic region     (about GC identifiers)

Start:
34,901,995 bp from pter      End:
34,931,562 bp from pter
Size:
29,568 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SPTSA_HUMAN, Q969W0 (See protein sequence)
Recommended Name: Serine palmitoyltransferase small subunit A  
Size: 71 amino acids; 8466 Da
Subunit: Interacts with SPTLC1; the interaction is direct. Component of the serine palmitoyltransferase (SPT)
complex, composed of SPTLC1, either SPTLC2 or SPTLC3, and either SPTSSA or SPTSSB
Caution: It is uncertain whether Met-1 or Met-4 is the initiator
Sequence caution: Sequence=AAH16805.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH16808.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH21701.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH68480.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAG37801.1; Type=Erroneous initiation;
Note=Translation N-terminally extended;
Secondary accessions: B2RD54 D3DS93 Q8WTZ7

Explore the universe of human proteins at neXtProt for SPTSSA: NX_Q969W0

Explore proteomics data for SPTSSA at MOPED


See SPTSSA Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_612145.2  
ENSEMBL proteins: 
 ENSP00000298130  

SPTSSA Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR024512 Ser_palmitoyltrfase_ssu-like

Graphical View of Domain Structure for InterPro Entry Q969W0

ProtoNet protein and cluster: Q969W0

UniProtKB/Swiss-Prot: SPTSA_HUMAN, Q969W0
Similarity: Belongs to the SPTSS family. SPTSSA subfamily


Find genes that share domains with SPTSSA           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: SPTSA_HUMAN, Q969W0
Function: Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine
palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a
strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as
substrates, with a slight preference for C14-CoA

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004758contributes to serine C-palmitoyltransferase activity IDA19416851
GO:0005515protein binding IPI19416851
     
Find genes that share ontologies with SPTSSA           About GenesLikeMe


Phenotypes:
     1 MGI phenotypic allele for Sptssa (no phenotypes)

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Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPTSSA
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miRNA
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miRTarBase miRNAs that target SPTSSA:
hsa-mir-454-3p (MIRT039222), hsa-mir-221-3p (MIRT024140)

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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
SPTSA_HUMAN, Q969W0: Endoplasmic reticulum membrane; Multi-pass membrane protein (Potential)

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral component of membrane IEA--
GO:0017059serine C-palmitoyltransferase complex IDA19416851

Find genes that share ontologies with SPTSSA           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for SPTSSA About    
See pathways by source

SuperPathContained pathways About
1ceramide de novo biosynthesis
ceramide de novo biosynthesis


1 BioSystems Pathway for SPTSSA
    ceramide de novo biosynthesis



UniProtKB/Swiss-Prot: SPTSA_HUMAN, Q969W0
Pathway: Lipid metabolism; sphingolipid metabolism

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SPTSSA
Interactions:

    Search GeneGlobe Interaction Network for SPTSSA

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

Selected Interacting proteins for SPTSSA (Q969W02, 3 ENSP000002981304) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

InteractantInteraction Details
GeneCardExternal ID(s)
ENSG00000258947Q135093I2D: score=2 
TUBB3Q135093I2D: score=2 
TUBB4AP043503, ENSP000002640714I2D: score=1 STRING: ENSP00000264071
SPTLC1ENSP000002625544STRING: ENSP00000262554
SPTLC2ENSP000002164844STRING: ENSP00000216484
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0030148sphingolipid biosynthetic process TAS19416851

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for SPTSSA (SPTSA)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for SPTSSA gene: 
NM_138288.3  

1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000298130(uc001wsc.3)
miRNA
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Primer
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OriGene qPCR primer pairs and template standards for SPTSSA
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  QuantiFast Probe-based Assays in human, mouse, rat SPTSSA

Selected AceView cDNA sequences (see all 299):

AA806547 AI339558 AW629678 CD515459 BQ228260 BU689196 BU687716 BI821640 
AI354441 CR616537 AI863488 AI348514 CA488763 BE738425 AI573090 AW079261 
AA040270 BX379451 CA775902 BI917628 AV682125 AI093156 AI394255 NM_138288 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SPTSSA expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TGTTGTGTTC
SPTSSA Expression
About this image

SPTSSA Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

SPTSSA Protein Expression
    Custom PCR Arrays for SPTSSA
Primer
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPTSSA

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for SPTSSA gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Sptssa1 , 5 RIKEN cDNA 1110002B05 gene5
serine palmitoyltransferase, small subunit A1
91.08(n)1
98.59(a)1
  12 (23.46 cM)5
1047251  NM_134054.21  NP_598815.21 
 546453745 
chicken
(Gallus gallus)
Aves SPTSSA1 serine palmitoyltransferase, small subunit A 87.75(n)
95.59(a)
  423318  XM_421234.4  XP_421234.2 
lizard
(Anolis carolinensis)
Reptilia SPTSSA6
serine palmitoyltransferase, small subunit A
94(a)
1 ↔ 1
2(54806441-54811985)
African clawed frog
(Xenopus laevis)
Amphibia BQ385602.12   -- 83.87(n)    BQ385602.1 
zebrafish
(Danio rerio)
Actinopterygii wufb60h112 wufb60h11 74.68(n)   322432  BM776360.1 


ENSEMBL Gene Tree for SPTSSA (if available)
TreeFam Gene Tree for SPTSSA (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for SPTSSA gene
SPTSSB2  
1 SIMAP similar gene for SPTSSA using alignment to 1 protein entry:     SPTSA_HUMAN:
SPTSSB

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1 Pseudogenes.org Pseudogene for SPTSSA
PGOHUM00000244865


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for SPTSSA (see all 741)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 14 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1864125641,2
--34901676(+) AATTAC/GAATGA 1 -- ds50010--------
rs1443215531,2
C--34901855(+) TTGTTA/GTCTTA 1 -- ds50010--------
rs1487670771,2
--34901862(+) CTTATC/TTTTAA 1 -- ds50010--------
rs1125839141,2
C,F--34901928(+) CATCAC/ACATCA 1 -- ds50011Minor allele frequency- A:0.50CSA 2
rs287221311,2
C,F--34901977(+) GAAGGC/GTCAAA 1 -- ds50015Minor allele frequency- G:0.27NA CSA WA 126
rs284486601,2
C,F,H--34902033(+) AGGTAA/C/TATTGG 1 -- ds50019NS NA CSA WA 1014
rs1154118921,2
C,F--34902088(+) CTACAG/AGATGG 1 -- ds50011Minor allele frequency- A:0.05WA 118
rs1920849821,2
--34902116(+) TATGCA/CGGGGA 1 -- ds50010--------
rs286875041,2
C,F--34902378(+) AAGACC/TAAACT 1 -- ut315Minor allele frequency- T:0.29NA CSA WA 125
rs1471661891,2
C--34902497(+) GCCAGA/GATAGG 1 -- ut310--------

HapMap Linkage Disequilibrium report for SPTSSA (34901995 - 34931562 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for SPTSSA:    About this table    
Variant IDTypeSubtypePubMed ID
nsv901600CNV Gain21882294
nsv528989CNV Gain19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing SPTSSA
DNA2.0 Custom Variant and Variant Library Synthesis for SPTSSA

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 613540    OMIM disorders: --


Find genes that share disorders with SPTSSA           About GenesLikeMe


Export disorders for SPTSSA gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for SPTSSA gene integrated from 10 sources:
(articles sorted by number of sources associating them with SPTSSA)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities. (PubMed id 19416851)1, 2, 3 Han G.... Dunn T.M. (Proc. Natl. Acad. Sci. U.S.A. 2009)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  4. Identification of small subunit of serine palmitoyltransferase a as a lysophosphatidylinositol acyltransferase 1-interacting protein. (PubMed id 23510452)1 Hirata Y....Arai H. (amp 2013)
  5. Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PubMed id 21103663)1 Schaafhausen A....MA1ller C.R. (Thromb. Haemost. 2011)
  6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
  7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  8. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 171546 HGNC: 20361 AceView: C14orf147 Ensembl:ENSG00000165389 euGenes: HUgn171546
ECgene: SPTSSA H-InvDB: SPTSSA

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for SPTSSA Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SPTSSA gene:
Search GeneIP for patents involving SPTSSA

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SPTSSA  
 OriGene qPCR primer pairs and template standards for SPTSSA   OriGene Protein Over-expression Lysate for SPTSSA  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for SPTSSA  
 Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for SPTSSA   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for SPTSSA   OriGene Custom Protein Services for SPTSSA  

 
 
 Block miRNA regulation of human, mouse, rat SPTSSA using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SPTSSA
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPTSSA Predesigned siRNA for gene silencing in human, mouse, rat SPTSSA
 QuantiFast Probe-based Assays in human, mouse, rat SPTSSA QuantiTect SYBR Green Assays in human, mouse, rat SPTSSA
 Custom PCR Arrays for SPTSSA Search Chromatin IP Primers for SPTSSA
 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat SPTSSA Search GeneGlobe Interaction Network for SPTSSA
 Search Regulatory tfbs for SPTSSA
 GenScript Custom Purified and Recombinant Proteins Services for SPTSSA GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for SPTSSA
 GenScript Custom Assay Services for SPTSSA GenScript Custom overexpressing Cell Line Services for SPTSSA
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
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 Search Tocris compounds for SPTSSA (SPTSA)
 Browse Sino Biological Proteins
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 cDNA Clones for SPTSSA
 4000+ Proteins
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 Protein Production Services
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 SPTSSA lysates
 Search for Antibodies for SPTSSA at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for SPTSSA
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for SPTSSA
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPTSSA
 SwitchGear 3'UTR luciferase reporter plasmids for SPTSSA
 SwitchGear Promoter luciferase reporter plasmids for SPTSSA
 Search ThermoFisher Antibodies for SPTSSA
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPTSSA
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPTSSA
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SPTSSA
 Search LSBio for Antibodies for SPTSSA
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for SPTSSA
  Search eBioscience for proteins for SPTSSA
  Search eBioscience for elisas for SPTSSA
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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