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Aliases for SPRYD7 Gene

Aliases for SPRYD7 Gene

  • SPRY Domain Containing 7 2 3
  • C13orf1 3 4 6
  • CLLD6 3 4 6
  • Chronic Lymphocytic Leukemia Deletion Region Gene 6 Protein 3 4
  • CLL Deletion Region Gene 6 Protein 3 4
  • Chromosome 13 Open Reading Frame 1 2
  • SPRY Domain-Containing Protein 7 3

External Ids for SPRYD7 Gene

Previous Symbols for SPRYD7 Gene

  • C13orf1

Summaries for SPRYD7 Gene

GeneCards Summary for SPRYD7 Gene

SPRYD7 (SPRY Domain Containing 7) is a Protein Coding gene. Diseases associated with SPRYD7 include chronic lymphocytic leukemia.

Gene Wiki entry for SPRYD7 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPRYD7 Gene

Genomics for SPRYD7 Gene

Genomic Location for SPRYD7 Gene

Start:
49,912,706 bp from pter
End:
49,936,490 bp from pter
Size:
23,785 bases
Orientation:
Minus strand

Genomic View for SPRYD7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPRYD7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPRYD7 Gene

No data available for Regulatory Elements for SPRYD7 Gene

Proteins for SPRYD7 Gene

  • Protein details for SPRYD7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5W111-SPRY7_HUMAN
    Recommended name:
    SPRY domain-containing protein 7
    Protein Accession:
    Q5W111
    Secondary Accessions:
    • A8K3G1
    • O60648
    • Q8TBG8
    • Q96T69

    Protein attributes for SPRYD7 Gene

    Size:
    196 amino acids
    Molecular mass:
    21666 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC09363.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for SPRYD7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SPRYD7 Gene

Proteomics data for SPRYD7 Gene at MOPED

Post-translational modifications for SPRYD7 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys85

Other Protein References for SPRYD7 Gene

No data available for DME Specific Peptides for SPRYD7 Gene

Domains for SPRYD7 Gene

Protein Domains for SPRYD7 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

SPRY7_HUMAN
Domain:
  • Contains 1 B30.2/SPRY domain.:
    • Q5W111
genes like me logo Genes that share domains with SPRYD7: view

No data available for Gene Families for SPRYD7 Gene

Function for SPRYD7 Gene

Gene Ontology (GO) - Molecular Function for SPRYD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with SPRYD7: view

Phenotypes for SPRYD7 Gene

GenomeRNAi human phenotypes for SPRYD7:
genes like me logo Genes that share phenotypes with SPRYD7: view

miRNA for SPRYD7 Gene

miRTarBase miRNAs that target SPRYD7

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SPRYD7 Gene

Localization for SPRYD7 Gene

No data available for Gene Ontology (GO) - Cellular Components for SPRYD7 Gene

Pathways for SPRYD7 Gene

SuperPathways for SPRYD7 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SPRYD7 Gene

None

No data available for Pathways by source for SPRYD7 Gene

Transcripts for SPRYD7 Gene

Unigene Clusters for SPRYD7 Gene

SPRY domain containing 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPRYD7 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d
SP1:
SP2: - -
SP3: - - -
SP4: -

Relevant External Links for SPRYD7 Gene

GeneLoc Exon Structure for
SPRYD7
ECgene alternative splicing isoforms for
SPRYD7

Expression for SPRYD7 Gene

mRNA expression in normal human tissues for SPRYD7 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SPRYD7 Gene

SOURCE GeneReport for Unigene cluster for SPRYD7 Gene Hs.44235

genes like me logo Genes that share expressions with SPRYD7: view

Orthologs for SPRYD7 Gene

This gene was present in the common ancestor of animals.

Orthologs for SPRYD7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SPRYD7 36
  • 99.66 (n)
  • 99.49 (a)
SPRYD7 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SPRYD7 36
  • 94.05 (n)
  • 98.47 (a)
SPRYD7 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SPRYD7 36
  • 94.2 (n)
  • 98.76 (a)
SPRYD7 37
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Spryd7 36
  • 90.48 (n)
  • 98.47 (a)
Spryd7 16
Spryd7 37
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SPRYD7 37
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SPRYD7 37
  • 94 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Spryd7 36
  • 90.48 (n)
  • 98.47 (a)
chicken
(Gallus gallus)
Aves SPRYD7 36
  • 82.99 (n)
  • 95.41 (a)
SPRYD7 37
  • 95 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SPRYD7 37
  • 85 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.24473 36
tropical clawed frog
(Silurana tropicalis)
Amphibia spryd7 36
  • 80.28 (n)
  • 93.72 (a)
Str.11085 36
zebrafish
(Danio rerio)
Actinopterygii Dr.13478 36
spryd7a 36
  • 74.49 (n)
  • 82.14 (a)
spryd7a 37
  • 82 (a)
OneToMany
spryd7b 37
  • 85 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001349 36
  • 51.66 (n)
  • 53.4 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7785 36
  • 53.68 (n)
  • 49.47 (a)
CG7785 37
  • 36 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F18H3.1 36
  • 54.69 (n)
  • 47.31 (a)
F18H3.1 37
  • 39 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 50 (a)
OneToOne
Species with no ortholog for SPRYD7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SPRYD7 Gene

ENSEMBL:
Gene Tree for SPRYD7 (if available)
TreeFam:
Gene Tree for SPRYD7 (if available)

Paralogs for SPRYD7 Gene

Pseudogenes.org Pseudogenes for SPRYD7 Gene

genes like me logo Genes that share paralogs with SPRYD7: view

No data available for Paralogs for SPRYD7 Gene

Variants for SPRYD7 Gene

Sequence variations from dbSNP and Humsavar for SPRYD7 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs1063181 -- 49,936,265(-) CTAGG(C/G)ACGGC utr-variant-5-prime, nc-transcript-variant
rs1063183 -- 49,914,947(-) GATGC(C/T)GTCTA utr-variant-3-prime, nc-transcript-variant
rs1609571 -- 49,914,719(-) GGGTG(G/T)GTGTT utr-variant-3-prime, nc-transcript-variant
rs2181267 -- 49,931,930(+) GCGAG(A/G)GAAGT intron-variant
rs2181268 -- 49,931,967(+) AACTG(C/T)AATAA intron-variant

Relevant External Links for SPRYD7 Gene

HapMap Linkage Disequilibrium report
SPRYD7

No data available for Structural Variations from Database of Genomic Variants (DGV) for SPRYD7 Gene

Disorders for SPRYD7 Gene

genes like me logo Genes that share disorders with SPRYD7: view

No data available for UniProtKB/Swiss-Prot for SPRYD7 Gene

Publications for SPRYD7 Gene

  1. Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia. (PMID: 11306461) Mabuchi H. … Croce C.M. (Cancer Res. 2001) 2 3 4
  2. [Transcription map of the 13q14 region, frequently deleted in B-cell chronic lymphocytic leukemia patients]. (PMID: 11771308) Tiazhelova T.V. … Baranova A.V. (Genetika 2001) 2 3
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Large-scale analysis of the human ubiquitin-related proteome. (PMID: 16196087) Matsumoto M. … Nakayama K.I. (Proteomics 2005) 3

Products for SPRYD7 Gene

Sources for SPRYD7 Gene

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