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Aliases for SPRY4-IT1 Gene

Subcategory (RNA class) for SPRY4-IT1 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for SPRY4-IT1 Gene

  • SPRY4 Intronic Transcript 1 2 3
  • SPRY4 Intronic Transcript 1 (Non-Protein Coding) 2

External Ids for SPRY4-IT1 Gene

Summaries for SPRY4-IT1 Gene

Entrez Gene Summary for SPRY4-IT1 Gene

  • This gene produces a non-coding RNA that is upregulated in several different tumors, including melanoma and breast and prostate cancer cells. This transcript may mediate cell growth, proliferation, and apoptosis. It regulates levels of lipin 2, and therefore may be involved in lipid biosynthesis. The primary transcript is cleaved to release a mature product that localizes to the cytoplasm (PMID:25344859). The full length structure of the primary and cleaved transcripts is unclear, and it is possible that the primary transcript is a splice variant of SPRY4 (GeneID:81848). [provided by RefSeq, Mar 2015]

GeneCards Summary for SPRY4-IT1 Gene

SPRY4-IT1 (SPRY4 Intronic Transcript 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPRY4-IT1 Gene

Genomics for SPRY4-IT1 Gene

Genomic Location for SPRY4-IT1 Gene

Unknown strand

Genomic View for SPRY4-IT1 Gene

Cytogenetic band:

No data available for Regulatory Elements and RefSeq DNA sequence for SPRY4-IT1 Gene

Proteins for SPRY4-IT1 Gene

Post-translational modifications for SPRY4-IT1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SPRY4-IT1 Gene

Domains for SPRY4-IT1 Gene

Gene Families for SPRY4-IT1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPRY4-IT1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SPRY4-IT1 Gene

Function for SPRY4-IT1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPRY4-IT1 Gene

Localization for SPRY4-IT1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SPRY4-IT1 Gene

Pathways for SPRY4-IT1 Gene

SuperPathways for SPRY4-IT1 Gene

No Data Available

Interacting Proteins for SPRY4-IT1 Gene

Gene Ontology (GO) - Biological Process for SPRY4-IT1 Gene


No data available for Pathways by source for SPRY4-IT1 Gene

Transcripts for SPRY4-IT1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for SPRY4-IT1 Gene

No ASD Table

Relevant External Links for SPRY4-IT1 Gene

ECgene alternative splicing isoforms for

No data available for mRNA/cDNA for SPRY4-IT1 Gene

Expression for SPRY4-IT1 Gene

mRNA expression in normal human tissues for SPRY4-IT1 Gene

mRNA expression in normal human tissues for SPRY4-IT1 Gene

SOURCE GeneReport for Unigene cluster for SPRY4-IT1 Gene Hs.684549

genes like me logo Genes that share expressions with SPRY4-IT1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for SPRY4-IT1 Gene

Orthologs for SPRY4-IT1 Gene

No data available for Orthologs and Evolution for SPRY4-IT1 Gene

Paralogs for SPRY4-IT1 Gene

No data available for Paralogs for SPRY4-IT1 Gene

Variants for SPRY4-IT1 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SPRY4-IT1 Gene

Disorders for SPRY4-IT1 Gene

No disorders were found for SPRY4-IT1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SPRY4-IT1 Gene

Publications for SPRY4-IT1 Gene

  1. The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. (PMID: 21558391) Khaitan D. … Perera R.J. (Cancer Res. 2011) 2 3
  2. Long noncoding RNA SPRY4-IT1 is upregulated in esophageal squamous cell carcinoma and associated with poor prognosis. (PMID: 24810925) Xie H.W. … Cao X.F. (Tumour Biol. 2014) 3
  3. EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promotes NSCLC cell proliferation and metastasis by affecting the epithelial-mesenchymal transition. (PMID: 24967960) Sun M. … Wang Z.X. (Cell Death Dis 2014) 3
  4. Long noncoding RNAs as putative biomarkers for prostate cancer detection. (PMID: 25307116) Lee B. … Perera R.J. (J Mol Diagn 2014) 3
  5. The long noncoding RNA SPRY4-IT1 increases the proliferation of human breast cancer cells by upregulating ZNF703 expression. (PMID: 25742952) Shi Y. … Shu Y. (Mol. Cancer 2015) 3

Products for SPRY4-IT1 Gene

Sources for SPRY4-IT1 Gene

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