SPRY3 Gene
protein-coding GIFtS: 51
GCID: GC0XP154997
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sprouty homolog 3 (Drosophila)(Previous name: sprouty (Drosophila) homolog 2 )
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Aliases for SPRY3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Sprouty Homolog 3 (Drosophila)1 2 | | Protein Sprouty Homolog 32 | | HSPRY31 2 | | Spry-33 | | Sprouty (Drosophila) Homolog 21 | | Spry-33 | | Antagonist Of FGF Signaling2 | | |
Export aliases for SPRY3 gene to outside databasesPrevious GC identifers: GC00U990472 GC0YM050220 GC0XP153429 GC0YP057438 GC0XP154561 GC0XP154650 GC0XP143477 |
Summaries for SPRY3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SPY3_HUMAN, O43610Function: May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulaterespiratory organogenesis Gene Wiki entry for SPRY3
|
Genomic Views for SPRY3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_000024.9 NC_018934.1 NT_167198.1 NT_167206.1
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SPRY3 gene promoter: HFH-1 Nkx2-2 Nkx2-5 Tal-1beta E47 Other transcription factors
Search SABiosciences Chromatin IP Primers for SPRY3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPRY3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq28 and Yq12 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28 and Yq12SPRY3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP154997: view genomic region
(about GC identifiers)
Start:
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154,997,451 bp from pter |
End:
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155,012,121 bp from pter |
Size:
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14,671 bases |
Orientation:
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plus strand |
1 alternative location:
| ChrY+ 59,100,457-59,115,123 |
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Proteins for SPRY3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SPY3_HUMAN, O43610 (See
protein sequence)Recommended Name: Protein sprouty homolog 3 Size: 288 amino acids; 31222 Da
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulatedcells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor)
Miscellaneous: The gene encoding for this protein is located in the pseudoautosomal region 2 (PAR2) of X and Ychromosomes
Sequence caution: Sequence=AAC39567.1; Type=Frameshift; Positions=96;
Secondary accessions: A8K0H8Explore the universe of human proteins at neXtProt for SPRY3: NX_O43610
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43610 SPRY3 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_005831.1 ENSEMBL proteins: ENSP00000302978 Human Recombinant Protein Products for SPRY3:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
SPRY3 for ontologies About GeneDecksing
SPRY3 Antibody Products: Assay Products for SPRY3: |
Protein
Domains / Families for SPRY3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SPRY3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O43610ProtoNet protein and cluster: O43610 1 Blocks protein family: IPB007875 Sprouty
UniProtKB/Swiss-Prot: SPY3_HUMAN, O43610Domain: The Cys-rich domain is responsible for the localization of the protein to the membrane rufflesSimilarity: Belongs to the sprouty familySimilarity: Contains 1 SPR (sprouty) domain |
Function for SPRY3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: SPY3_HUMAN, O43610Function: May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulaterespiratory organogenesisInduction: By FGF signaling Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0005515 | protein binding |
-- | -- |
SPRY3 for ontologies About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPRY3 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPRY3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SPRY3 (NM_005840) | |  | Sino Biological Human cDNA Clone for SPRY3 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPRY3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPRY3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPRY3 |
|
Pathways & Interactions for SPRY3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Jak-STAT signaling pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Kegg Pathway (Kegg details for SPRY3):
SPRY3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SPRY3
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
 4 Interacting proteins for SPRY3 (O436103 ENSP000003029784) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007275 | multicellular organismal development |
NAS | 9458049 | | GO:0009966 | regulation of signal transduction |
IEA | -- |
SPRY3 for ontologies About GeneDecksing
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Drugs & Compounds for SPRY3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SPRY3 Search CenterWatch for drugs/clinical trials and news about SPRY3 / SPY3 
|
Transcripts for SPRY3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SPRY3 gene: NM_005840.1 Unigene Cluster for SPRY3: Sprouty homolog 3 (Drosophila) Hs.381912 [show with all ESTs]Unigene Representative Sequence: NM_0058401 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000302805(uc004fnq.1)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPRY3 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPRY3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SPRY3 (NM_005840) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPRY3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPRY3  |
Additional cDNA sequence: AF041038.1 AK094610.1 AK125483.1 AK289543.1 AK311508.1 BC069609.1 BC074972.2 BC074973.2 5 DOTS entries: DT.110016 DT.120654065 DT.120654064 DT.40286527 DT.91907383 24/34 AceView cDNA sequences (see all 34): BC074973 BC069609 N52233 NM_005840 BC074972 H24223 BU164699 BQ228300 AI754212 AA994998 AK125483 AA682860 AA933967 R42219 BM311383 BQ012402 BU685186 BX115815 AA650036 BM932153 N73200 AI038709 BM311977 X97511 GeneLoc Exon Structure
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Expression for SPRY3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SPRY3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GAAAGCCAAG
 About this image See SPRY3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SPRY3
SOURCE GeneReport for Unigene cluster: Hs.381912
UniProtKB/Swiss-Prot: SPY3_HUMAN, O43610Tissue specificity: Widely expressed; particularly in the fetal tissues SABiosciences Custom PCR Arrays for SPRY3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPRY3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SPRY3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPRY3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPRY3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPRY3 |
Orthologs for SPRY3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SPRY3 gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
SPRY31 |
sprouty homolog 3 (Drosophila) |
70.7(n) 66.55(a) |
  |
428712 NM_001079736.1 NP_001073204.1 |
lizard (Anolis carolinensis) |
Reptilia |
SPRY36 |
-- |
59(a) |
1 ↔ 1 |
GL343202.1(2023560-2024420) |
zebrafish (Danio rerio) |
Actinopterygii |
wufk66h112 |
Transcribed sequence with moderate similarity to protein more |
75.45(n) |
  |
57092611 |
fruit fly (Drosophila melanogaster) |
Insecta |
sty6 |
sprouty |
14(a) |
1 → many |
3L(3401137-3424935) |
ENSEMBL Gene Tree for SPRY3 (if available) TreeFam Gene Tree for SPRY3 (if available)  |
Paralogs for SPRY3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SPRY3 gene
- SPRY12 SPRY22 SPRY42
3 SIMAP similar genes for SPRY3 using alignment to 1 protein entry: SPY3_HUMAN:SPRY2 SPRY4 SPRY1
SPRY3 for paralogs About GeneDecksing
|
Genomic Variants for SPRY3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for SPRY3 1 CNV: 0828 Human Gene Mutation Database (HGMD): SPRY3
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPRY3 |
|
Disorders
/ Diseases for SPRY3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SPRY3 for disorders About MalaCards
SPRY3 for disorders About GeneDecksing
OMIM gene information: 300531
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: SPRY3 (1 document) Export disorders for SPRY3 gene to outside databases
|
Publications for SPRY3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SPRY3 gene, integrated from 9 sources (see all 13): (articles sorted by number of sources associating them with SPRY3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. (PubMed id 9458049)1, 2, 3 Hacohen N.... Krasnow M.A. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region. (PubMed id 10655549)1, 2 Ciccodicola A.... D'Urso M. (2000)
- Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling. (PubMed id 17974561)1 Chandramouli S....Guy G.R. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- A functional interaction between sprouty proteins and caveolin-1. (PubMed id 16877379)1 Cabrita M.A....Christofori G. (2006)
- Maintenance of X- and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications. (PubMed id 16500999)1 De Bonis M.L....D'Esposito M. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- Human placental Hofbauer cells express sprouty proteins: a possible modulating mechanism of villous branching. (PubMed id 15950061)1 Anteby E.Y....Yagel S. (2005)
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External Searches for SPRY3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
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Genome Databases showing SPRY3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SPRY3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SPRY3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SPRY3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SPRY3 gene: Search GeneIP for patents involving SPRY3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for SPRY3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SPRY3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SPRY3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPRY3 | | OriGene Protein Over-expression Lysate for SPRY3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SPRY3 | | OriGene 3'-UTR Clone for SPRY3 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPRY3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPRY3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SPRY3 | | OriGene Custom Protein Services for SPRY3 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPRY3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPRY3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPRY3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPRY3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPRY3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPRY3 |
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 | | SPRY3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPRY3 |
|  |  |  |  | | | Search ThermoFisher Antibodies for SPRY3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPRY3 |
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