Aliases for SPRR1B Gene
External Ids for SPRR1B Gene
Previous HGNC Symbols for SPRR1B Gene
Previous GeneCards Identifiers for SPRR1B Gene
GeneCards Summary for SPRR1B Gene
SPRR1B (Small Proline-Rich Protein 1B) is a Protein Coding gene. Diseases associated with SPRR1B include epidermolytic hyperkeratosis. GO annotations related to this gene include structural molecule activity and protein binding, bridging. An important paralog of this gene is SPRR3.
UniProtKB/Swiss-Prot for SPRR1B Gene
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage