SPOP Gene
protein-coding GIFtS: 56
GCID: GC17M047676
|
|
speckle-type POZ protein
| |
Aliases
for SPOP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Speckle-Type POZ Protein1 2 | | BTBD321 2 | | TEF21 2 | | Roadkill Homolog 12 3 | | HIB Homolog 12 3 |
Export aliases for SPOP gene to outside databasesPrevious GC identifers: GC17M047388 GC17M050157 GC17M048019 GC17M048152 GC17M045032 GC17M043042 |
Summaries
for SPOP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SPOP:
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6(DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, theencoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched oninactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediatetranscriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternativesplicing of this gene results in multiple transcript variants encoding the same protein. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: SPOP_HUMAN, O43791Function: Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting arepressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, andprobably also in ubiquitination and proteasomal degradation of Gli2 or Gli3
Gene Wiki entry for SPOP
|
Genomic Views
for SPOP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SPOP gene promoter:
NF-1 NF-1/L GATA-3 AREB6 CREB POU2F1 POU2F1a deltaCREB Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for SPOP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPOP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q21.33 Ensembl cytogenetic band: 17q21.33 HGNC cytogenetic band: 17q21.33SPOP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M047676: view genomic region
(about GC identifiers)
Start:
|
47,676,246 bp from pter |
End:
|
47,755,596 bp from pter |
Size:
|
79,351 bases |
Orientation:
|
minus strand |
|
Proteins
for SPOP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SPOP_HUMAN, O43791 (See
protein sequence)Recommended Name: Speckle-type POZ protein Size: 374 amino acids; 42132 Da
Subunit: Homodimer. Part of a complex consisting of BMI1, CUL3 and SPOP. Part of a complex consisting of H2AFY, CUL3and SPOP. Part of a complex consisting of DAXX, CUL3 and SPOP. Interacts with H2AFY, IPF1/PDX1, BMI1 and DAXX.Interacts with CUL3
Subcellular location: Nucleus
Miscellaneous: Antigen recognized by serum from scleroderma patient
6/11 PDB 3D structures from  and Proteopedia  for SPOP (see all 11):2CR2 (3D)
3HQH (3D)
3HQI (3D)
3HQL (3D)
3HQM (3D)
3HTM (3D)
Secondary accessions: B2R6S3 D3DTW7 Q53HJ1Explore the universe of human proteins at neXtProt for SPOP: NX_O43791
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43791
SPOP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001007227.1 NP_001007228.1 NP_001007229.1 NP_001007230.1 NP_001007231.1 NP_003554.1
ENSEMBL proteins: ENSP00000377001 ENSP00000425905 ENSP00000420908 ENSP00000423284 ENSP00000426986 ENSP00000420960 ENSP00000425604 ENSP00000426262 ENSP00000424119 ENSP00000426537 ENSP00000422609 ENSP00000425410 ENSP00000427419 ENSP00000423076 ENSP00000377004 ENSP00000240327
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
SPOP for ontologies About GeneDecksing
SPOP Antibody Products:
Assay Products for SPOP: |
Protein
Domains /
Families
for SPOP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SPOP for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43791ProtoNet protein and cluster: O43791 2 Blocks protein families: IPB000210 BTB/POZ domain IPB002083 Meprin/TRAF-like MATH
UniProtKB/Swiss-Prot: SPOP_HUMAN, O43791Domain: The MATH domain interacts with H2AFY and BMI1Similarity: Belongs to the Tdpoz familySimilarity: Contains 1 BTB (POZ) domainSimilarity: Contains 1 MATH domain |
Function
for SPOP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SPOP_HUMAN, O43791Function: Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting arepressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, andprobably also in ubiquitination and proteasomal degradation of Gli2 or Gli3
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPOP (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPOP (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 6): SPOP (NM_001007229) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPOP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPOP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPOP |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SPOP for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for SPOP:
Animal Models:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Spop):
SPOP for phenotypes About GeneDecksing
|
Pathways & Interactions
for SPOP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Hedgehog signaling events mediated by Gli proteins | | | 2 | mRNA Splicing - Major Pathway | |
2  BioSystems Pathways for SPOP
UniProtKB/Swiss-Prot: SPOP_HUMAN, O43791Pathway: Protein modification; protein ubiquitinationInteractions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SPOP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/39 Interacting proteins for SPOP (O437911, 2, 3 ENSP000002403274) via UniProtKB, MINT, STRING, and/or I2D (see all 39) | Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| RXRB | P287022, 3, ENSP000003638124 | MINT-67766 I2D:
score=5 STRING: ENSP00000363812 | | CUL3 | Q136181, 3, ENSP000002644144 | EBI-743549,EBI-456129 I2D:
score=1 STRING: ENSP00000264414 | | DPPA2 | Q7Z7J52, 3 | MINT-66743 I2D:
score=4 | | MYD88 | Q998361, 2, 3, ENSP000003796254 | EBI-743549,EBI-447677 MINT-68208 I2D:
score=5 STRING: ENSP00000379625 | | NCOA3 | Q9Y6Q91, 3, ENSP000003610664 | EBI-743549,EBI-81196 I2D:
score=1 STRING: ENSP00000361066 |
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
SPOP for ontologies About GeneDecksing
|
Drugs & Compounds
for SPOP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SPOP
Search CenterWatch for drugs/clinical trials and news about SPOP
|
Transcripts
for SPOP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SPOP gene (6 alternative transcripts): NM_001007226.1 NM_001007227.1 NM_001007228.1 NM_001007229.1 NM_001007230.1 NM_003563.3 Unigene Cluster for SPOP: Speckle-type POZ protein Hs.740407 [show with all ESTs]Unigene Representative Sequence: AK12508718/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000393328 ENST00000572686 ENST00000504102 ENST00000503676 ENST00000577134
ENST00000507551 ENST00000504889 ENST00000509869 ENST00000509079 ENST00000505581
ENST00000506399 ENST00000507970 ENST00000514121 ENST00000515508 ENST00000513080
ENST00000504212 ENST00000510476 ENST00000508805
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPOP (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPOP (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 6): SPOP (NM_001007229) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPOP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPOP |
Additional cDNA sequence: AJ000644.1 AK123385.1 AK125087.1 AK222589.1 AK293045.1 AK293587.1 AK300616.1 AK303268.1 AK312691.1 AK316366.1 BC001269.1 BC003385.1 24/25 DOTS entries (see all 25): DT.120978981 DT.448401 DT.95227280 DT.92456693 DT.95227258 DT.97854871 DT.40265295 DT.92456692 DT.97854870 DT.100824392 DT.100824400 DT.120978997 DT.426759 DT.103866 DT.87079373 DT.100824391 DT.100824398 DT.205192 DT.100824386 DT.120978947 DT.120978950 DT.120978958 DT.120979033 DT.40257030 24/541 AceView cDNA sequences (see all 541): BE794609 BP358501 BP356911 AI572461 T33381 BQ670701 T35229 BQ226031 BP368336 BF110908 AI144300 H03857 AA506074 AA316374 BQ069826 BQ025597 T31510 AI206948 R37561 CR595475 AA377868 AA361694 BU736956 BF594743
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SPOP (see all 8) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b |
|---|
|
| SP1: | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | - | | | | | | | | |
| SP2: | | | | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SPOP
|
Expression
for SPOP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SPOP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTCGGATGT
About this image
See SPOP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SPOP
SOURCE GeneReport for Unigene cluster: Hs.740407
UniProtKB/Swiss-Prot: SPOP_HUMAN, O43791Tissue specificity: Widely expressed
SABiosciences Expression via Pathway-Focused PCR Array including SPOP:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPOP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SPOP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPOP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPOP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPOP |
Orthologs
for SPOP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SPOP gene from 9/23 species (see all 23) About this table
ENSEMBL Gene Tree for SPOP (if available)
TreeFam Gene Tree for SPOP (if available) |
Paralogs
for SPOP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SPOP gene
- SPOPL2
4 SIMAP similar genes for SPOP using alignment to 11 protein entries: SPOP_HUMAN (see all proteins):SPOPL BTBD3 KLHL24 ZNF131
SPOP for paralogs About GeneDecksing
|
Genomic Variants
for SPOP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SPOP (47676246 - 47755596 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SPOP: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPOP |
|
Disorders
/ Diseases
for SPOP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SPOP for disorders About GeneDecksing
OMIM gene information: 602650
OMIM disorders: --
6  diseases for SPOP: About MalaCardsmulibrey nanism scleroderma kidney cancer pharyngitis
breast cancer neuronitis
1 disease from the University of Copenhagen DISEASES database for SPOP:Mulibrey nanism Human Genome Epidemiology (HuGE) Navigator: SPOP (1 document)
Export disorders for SPOP gene to outside databases
|
Publications
for SPOP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SPOP gene, integrated from 9 sources (see all 43):
(articles sorted by number of sources associating them with SPOP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a novel nuclear speckle-type protein, SPOP. (PubMed id 9414087)1, 2, 3, 9 Nagai Y.... Hagiwara M. (1997)
- BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. (PubMed id 16524876)1, 2, 9 Kwon J.E.... Chung C.H. (2006)
- Daxx-mediated transcriptional repression of MMP1 gene is reversed by SPOP. (PubMed id 15240113)1, 2, 9 La M....Joe C.O. (2004)
- A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. (PubMed id 16740475)1, 2, 9 Zhang Q.... Jiang J. (2006)
- Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus. (PubMed id 16651542)1, 2 Kent D.... Hooper J.E. (2006)
- Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase. (PubMed id 15897469)1, 2 Hernandez-Munoz I....van Lohuizen M. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- BTB/POZ domain of speckle-type POZ protein (SPOP) confers proapoptotic function in HeLa cells. (PubMed id 18997279)1, 9 Byun B....Joe C.O. (2007)
- Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. (PubMed id 19818708)1, 9 Zhuang M....Schulman B.A. (2009)
|
External Searches for SPOP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SPOP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SPOP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SPOP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SPOP | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SPOP gene:
Search GeneIP for patents involving SPOP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SPOP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SPOP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SPOP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPOP | | | OriGene Protein Over-expression Lysate for SPOP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SPOP | | OriGene 3'-UTR Clone for SPOP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPOP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPOP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SPOP | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SPOP | | OriGene Custom Protein Services for SPOP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPOP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPOP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPOP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPOP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPOP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPOP |
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| | | | Search Tocris compounds for SPOP |
| |  |  |  |  | | | | | | Recombinant Protein for SPOP |
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 | | | SPOP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPOP |
|  |  |  | | | | ThermoFisher Antibodies for SPOP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPOP |
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