Aliases for SPOCK2 Gene
External Ids for SPOCK2 Gene
Previous GeneCards Identifiers for SPOCK2 Gene
This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for SPOCK2 Gene
SPOCK2 (SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 2) is a Protein Coding gene. Diseases associated with SPOCK2 include Endometriosis Of Ovary. Among its related pathways are Phospholipase-C Pathway and ERK Signaling. GO annotations related to this gene include calcium ion binding and extracellular matrix binding. An important paralog of this gene is SPOCK1.
UniProtKB/Swiss-Prot for SPOCK2 Gene
May participate in diverse steps of neurogenesis. Binds calcium.