Aliases for SPOCK2 Gene
External Ids for SPOCK2 Gene
Previous GeneCards Identifiers for SPOCK2 Gene
This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for SPOCK2 Gene
SPOCK2 (SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 2) is a Protein Coding gene. Diseases associated with SPOCK2 include Endometriosis Of Ovary. Among its related pathways are Integrin Pathway and ERK Signaling. GO annotations related to this gene include calcium ion binding and extracellular matrix binding. An important paralog of this gene is SPOCK3.
UniProtKB/Swiss-Prot for SPOCK2 Gene
May participate in diverse steps of neurogenesis. Binds calcium.