Aliases for SPIRE2 Gene
External Ids for SPIRE2 Gene
Previous GeneCards Identifiers for SPIRE2 Gene
GeneCards Summary for SPIRE2 Gene
SPIRE2 (Spire-Type Actin Nucleation Factor 2) is a Protein Coding gene. Among its related pathways are TGF-Beta Pathway and Dorso-ventral axis formation. GO annotations related to this gene include actin binding. An important paralog of this gene is SPIRE1.
UniProtKB/Swiss-Prot for SPIRE2 Gene
Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.