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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SPINK7 Gene

protein-coding GIFtS: 46
GCID: GC05P147691

serine peptidase inhibitor, Kazal type 7 (putative)

Explore 8 diseases affiliated with
SPINK7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Serine Peptidase Inhibitor, Kazal Type 7 (Putative)¹ ²		ECRG-2² ³
ECG2¹ ² ³		Esophagus Cancer Related Gene 2²
ECRG2¹ ²		Esophagus Cancer-Related Gene-2²
Esophagus Cancer-Related Gene 2 Protein² ³		Serine Protease Inhibitor Kazal-Type 7²

External Ids:	HGNC: 24643¹	Entrez Gene: 84651²	Ensembl: ENSG00000145879⁷	UniProtKB: P58062³

Export aliases for SPINK7 gene to outside databases

Previous GC identifers: GC05P147673 GC05P142839

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ISK7_HUMAN, P58062

Function: Probable serine protease inhibitor

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000005.9 NC_018916.1 NT_029289.11

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SPINK7 gene promoter:
C/EBPbeta Sox5 oct-B3 Bach2 Pax-6 MEF-2A POU2F1 HFH-1 aMEF-2 En-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SPINK7 promoter sequence

Search SABiosciences Chromatin IP Primers for SPINK7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPINK7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q32 Ensembl cytogenetic band: 5q32 HGNC cytogenetic band: 5q32

SPINK7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPINK7 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05P147691: view genomic region (about GC identifiers)

Start:	147,691,982 bp from pter	End:	147,695,485 bp from pter
Size:	3,504 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ISK7_HUMAN, P58062 (See protein sequence)

Recommended Name: Serine protease inhibitor Kazal-type 7 precursor

Size: 85 amino acids; 9232 Da

Subcellular location: Secreted (Potential)

1 PDB 3D structure from and Proteopedia for SPINK7:

2LEO (3D)

Secondary accessions: Q32LY0

Explore the universe of human proteins at neXtProt for SPINK7: NX_P58062

SPINK7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_115955.1

ENSEMBL proteins:

ENSP00000274565 ENSP00000427887

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	Uscn Proteins for SPINK7

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--

SPINK7 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SPINK7 for domains About GeneDecksing

1 InterPro domain/family:

IPR002350 Prot_inh_Kazal

Graphical View of Domain Structure for InterPro Entry P58062

ProtoNet protein and cluster: P58062

1 Blocks protein family: IPB001239 Kazal-type serine protease inhibitor signature

UniProtKB/Swiss-Prot: ISK7_HUMAN, P58062

Similarity: Contains 1 Kazal-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ISK7_HUMAN, P58062

Function: Probable serine protease inhibitor

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
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In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for SPINK7

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004867	serine-type endopeptidase inhibitor activity	IEA	--
GO:0005515	protein binding	IPI	12970870

SPINK7 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for SPINK7:

Decreased POU5F1-GFP protein e

Animal Models:
Mouse knock-out Spink7^tm1Lex for SPINK7
1 MGI phenotypic allele

for Spink7 (no phenotypes)

SPINK7 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SPINK7

STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

5/15 Interacting proteins for SPINK7 (P58062^{1, 3} ENSP00000274565⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 15)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EPB42	P16452¹^,³, ENSP00000300215⁴	EBI-1182445,EBI-1182496 I2D: score=4 STRING: ENSP00000300215
MRPS12	O15235¹^,³, ENSP00000308845⁴	EBI-1182445,EBI-712205 I2D: score=4 STRING: ENSP00000308845
MT1H	P80294¹^,³, ENSP00000330587⁴	EBI-1182445,EBI-296567 I2D: score=4 STRING: ENSP00000330587
MT2A	P02795¹^,³, ENSP00000245185⁴	EBI-1182445,EBI-996616 I2D: score=4 STRING: ENSP00000245185
RABL6	Q3YEC7¹^,³, ENSP00000311134⁴	EBI-1182445,EBI-742029 I2D: score=4 STRING: ENSP00000311134

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

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Browse Tocris compounds for SPINK7
Search CenterWatch for drugs/clinical trials and news about SPINK7 / ISK7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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About This Section

REFSEQ mRNAs for SPINK7 gene:

NM_032566.2

Unigene Cluster for SPINK7:

Serine peptidase inhibitor, Kazal type 7 (putative)

Hs.244569 [show with all ESTs]

Unigene Representative Sequence: AK311570

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000514394 ENST00000274565(uc003lpd.3) ENST00000514646 ENST00000504037

ENST00000523535

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		hsa-miR-149
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Additional cDNA sequence:

AF268198.1 AK311570.1 AY359072.1 BC109385.1 BC110067.1 U47646.1

3 DOTS entries:

DT.428158 DT.100018859 DT.92429545

24/53 AceView cDNA sequences (see all 53):

AY359072 BE141419 BE141410 NM_032566 BX280856 BE350358 AW238399 AF268198

AW082220 BE141373 BE141334 BE141366 AA773398 BM955684 BM955686 AA773866

BE141361 AW170024 BE141209 BF349223 BM955685 BE141368 BE141393 BE141299

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SPINK7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACATAGAGA

About this image

SPINK7 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

AII Amacrine Cells

Amacrine, Retina

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SPINK7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SPINK7

SOURCE GeneReport for Unigene cluster: Hs.244569

SABiosciences Custom PCR Arrays for SPINK7

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPINK7

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for SPINK7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for SPINK7 gene from 1/6 species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Spink7^{1 , 5}	serine peptidase inhibitor, Kazal type 7 (putative)^{1, 5}	76.08(n)¹ 67.06(a)¹		18 (35.33 cM)⁵ 408198¹ NM_001001803.2¹ NP_001001803.2¹ 62592413⁵

ENSEMBL Gene Tree for SPINK7 (if available)
TreeFam Gene Tree for SPINK7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SPINK7 gene

SPINK14²

10 SIMAP similar genes for SPINK7 using alignment to 2 protein entries: ISK7_HUMAN (see all proteins):

SPINK4 SPINK14 SPINK8 SPINK2 SPINK5 SPINK9

SPINK6 SLCO2A1 HEL-S-48e SPINK13

SPINK7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs117859782^1,2	F,	--	147690026(+)	`ACCCCG/AGACGC`	1	--	us2k¹		1		EA	120
rs59179092^1,2	C,F,	--	147690030(+)	`CGGACG/CCCATG`	1	--	us2k¹		2		WA EA	238
rs200247523^1,2		--	147690070(+)	`TGTGT-/GAGAGAG`	1	--	us2k¹		0	--	--	--	--
rs77194995^1,2	F,	--	147690098(+)	`CTAATT/GTAACA`	1	--	us2k¹		2		WA EA	238
rs58715347^1,2		--	147690262(+)	`ACTAGT/ATTACA`	1	--	us2k¹		1		CSA	2
rs17719614^1,2	C,F,H,	--	147690278(+)	`TCCCAA/GACAGA`	1	--	us2k¹ tfbs³		9		NA NS EA	684
rs139120114^1,2		--	147690284(+)	`ACAGAC/TATAGG`	1	--	us2k¹		0	--	--	--	--
rs188117158^1,2		--	147690311(+)	`TTATGC/TAATAT`	1	--	us2k¹		0	--	--	--	--
rs78274433^1,2	C,F,	--	147690363(+)	`AGAATG/TTACTA`	1	--	us2k¹		1		EA	120
rs192790783^1,2		--	147690481(+)	`TTGTGA/CATGGA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SPINK7 (147691982 - 147695485 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SPINK7: --
Human Gene Mutation Database (HGMD): SPINK7

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPINK7

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SPINK7 for disorders About GeneDecksing

8 diseases for SPINK7: About MalaCards

oral squamous cell carcinoma squamous cell carcinoma esophageal carcinoma esophagitis

esophageal cancer carcinoma pancreatic carcinoma pancreatitis

3 Novoseek disease relationships for SPINK7 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
esophageal carcinoma	65.2	3	17352218 (1), 17693286 (1), 12646258 (1)
tumors	3.56	3	12646258 (2)
cancer	0.79	1	12642876 (1)

Human Genome Epidemiology (HuGE) Navigator: SPINK7 (4 documents)

Export disorders for SPINK7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SPINK7 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with SPINK7)

Utopia: connect your pdf to the dynamic
world of online information

ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis. (PubMed id 12646258)^{1, 3, 9} Cui Y....Lu S.H. (2003)
Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene. (PubMed id 12970870)^{1, 3, 9} Cui Y.P....Lu S.H. (2003)
NMR structure note: human esophageal cancer-related ge ne 2. (PubMed id 22528291)^{1, 2} Feng Y....Wang J. (2012)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Mapping the putative binding site for uPA protein in Esophageal Cancer-Related Gene 2 by heteronuclear NMR method. (PubMed id 18824154)^{1, 9} Geng Y....Lu S.H. (2008)
Short tandem repeat polymorphisms of exon 4 in Kazal-type gene ECRG2 in pancreatic carcinoma and chronic pancreatitis. (PubMed id 17352218)^{1, 9} Kaifi J.T....Izbicki J.R. (2007)
Short tandem repeat polymorphism in exon 4 of esophageal cancer related gene 2 predicts relapse of oral squamous cell carcinoma. (PubMed id 17418617)^{1, 9} Blessmann M....Izbicki J.R. (2008)
Short tandem repeat polymorphism in exon 4 of esophageal cancer-related gene 2 detected in genomic DNA is a prognostic marker for esophageal cancer. (PubMed id 17693286)^{1, 9} Kaifi J.T....Izbicki J.R. (2007)
Short tandem repeat polymorphism in a novel esophageal cancer-related gene (ECRG2) implicates susceptibility to esophageal cancer in Chinese population. (PubMed id 14639608)^{1, 9} Yue C.M....Lu S.H. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84651	HGNC: 24643	AceView: ECG2	Ensembl:ENSG00000145879	euGenes: HUgn84651
ECgene: SPINK7	H-InvDB: SPINK7

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SPINK7	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for SPINK7	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for SPINK7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SPINK7 gene:
Search GeneIP for patents involving SPINK7

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
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About This Section


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	Browse OriGene Antibodies		OriGene shRNA RFP for SPINK7
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SPINK7		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPINK7
	OriGene Protein Over-expression Lysate for SPINK7		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SPINK7		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPINK7		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPINK7
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for SPINK7		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for SPINK7		OriGene Custom Protein Services for SPINK7
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPINK7
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPINK7
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPINK7
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPINK7
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPINK7
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPINK7

	GenScript Custom Purified and Recombinant Proteins Services for SPINK7		GenScript cDNA clones with any tag delivered in your preferred vector for SPINK7
	GenScript Custom Assay Services for SPINK7		GenScript Custom Superior Antibodies Services for SPINK7
	GenScript Custom overexpressing Cell Line Services for SPINK7		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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	SwitchGear 3'UTR luciferase reporter plasmids for SPINK7
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPINK7

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SPINK7 gene at Home site.

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SPINK7 Gene

serine peptidase inhibitor, Kazal type 7 (putative)

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SPINK7 Gene

serine peptidase inhibitor, Kazal type 7 (putative)

Aliasesfor SPINK7 gene

Summariesfor SPINK7 gene

Genomic Viewsfor SPINK7 gene

Proteinsfor SPINK7 gene

Protein Domains /Familiesfor SPINK7 gene

Functionfor SPINK7 gene

Pathways & Interactionsfor SPINK7 gene

Drugs & Compoundsfor SPINK7 gene

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Genome Databases showing SPINK7 gene

Other Databases showing SPINK7 gene

Specialized Databases showing SPINK7 gene

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Aliases
for SPINK7 gene

Summaries
for SPINK7 gene

Genomic Views
for SPINK7 gene

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for SPINK7 gene

Protein Domains /
Families
for SPINK7 gene

Function
for SPINK7 gene

Pathways & Interactions
for SPINK7 gene

Drugs & Compounds
for SPINK7 gene

Transcripts
for SPINK7 gene

Expression
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Orthologs
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Disorders / Diseases
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Publications
for SPINK7 gene

Intellectual Property
for SPINK7 gene

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for SPINK7 gene