Aliases for SPINK1 Gene
External Ids for SPINK1 Gene
Previous GeneCards Identifiers for SPINK1 Gene
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]
GeneCards Summary for SPINK1 Gene
SPINK1 (Serine Peptidase Inhibitor, Kazal Type 1) is a Protein Coding gene. Diseases associated with SPINK1 include pancreatitis, hereditary and tropical calcific pancreatitis. Among its related pathways are Prostate Cancer. GO annotations related to this gene include serine-type endopeptidase inhibitor activity and endopeptidase inhibitor activity.
UniProtKB/Swiss-Prot for SPINK1 Gene
This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas