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Aliases for SPIN3 Gene

Aliases for SPIN3 Gene

  • Spindlin Family, Member 3 2 3
  • Spindlin-Like Protein 3 3 4
  • SPIN-3 3 4
  • BA445O16.1 (DXF34) 3
  • BA445O16.1 3
  • Spindlin-3 3

External Ids for SPIN3 Gene

Summaries for SPIN3 Gene

GeneCards Summary for SPIN3 Gene

SPIN3 (Spindlin Family, Member 3) is a Protein Coding gene. An important paralog of this gene is SPIN2B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPIN3 Gene

Genomics for SPIN3 Gene

Genomic Location for SPIN3 Gene

Start:
56,976,370 bp from pter
End:
56,995,612 bp from pter
Size:
19,243 bases
Orientation:
Minus strand

Genomic View for SPIN3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPIN3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPIN3 Gene

Regulatory Elements for SPIN3 Gene

Proteins for SPIN3 Gene

  • Protein details for SPIN3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JUX0-SPIN3_HUMAN
    Recommended name:
    Spindlin-3
    Protein Accession:
    Q5JUX0
    Secondary Accessions:
    • B2RUW3
    • B7Z8W2
    • Q8N5D9

    Protein attributes for SPIN3 Gene

    Size:
    258 amino acids
    Molecular mass:
    29207 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPIN3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SPIN3 Gene

Proteomics data for SPIN3 Gene at MOPED

Post-translational modifications for SPIN3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPIN3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPIN3 Gene

Domains for SPIN3 Gene

Protein Domains for SPIN3 Gene

UniProtKB/Swiss-Prot:

SPIN3_HUMAN
Family:
  • Belongs to the SPIN/STSY family.:
    • Q5JUX0
genes like me logo Genes that share domains with SPIN3: view

No data available for Gene Families for SPIN3 Gene

Function for SPIN3 Gene

miRNA for SPIN3 Gene

miRTarBase miRNAs that target SPIN3

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SPIN3 Gene

Localization for SPIN3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SPIN3 Gene COMPARTMENTS Subcellular localization image for SPIN3 gene
Compartment Confidence
mitochondrion 3
cytosol 2
nucleus 2

No data available for Gene Ontology (GO) - Cellular Components for SPIN3 Gene

Pathways for SPIN3 Gene

SuperPathways for SPIN3 Gene

No Data Available

Interacting Proteins for SPIN3 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000364054%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000376609%0d%0a
Selected Interacting proteins: ENSP00000364054 Q5JUX0-SPIN3_HUMAN for SPIN3 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for SPIN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007276 gamete generation IEA --
genes like me logo Genes that share ontologies with SPIN3: view

No data available for Pathways by source for SPIN3 Gene

Transcripts for SPIN3 Gene

Unigene Clusters for SPIN3 Gene

Spindlin family, member 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPIN3 Gene

No ASD Table

Relevant External Links for SPIN3 Gene

GeneLoc Exon Structure for
SPIN3
ECgene alternative splicing isoforms for
SPIN3

Expression for SPIN3 Gene

mRNA expression in normal human tissues for SPIN3 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SPIN3 Gene

SOURCE GeneReport for Unigene cluster for SPIN3 Gene Hs.522672

genes like me logo Genes that share expressions with SPIN3: view

Orthologs for SPIN3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPIN3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SPIN3 36
  • 99.74 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia SPIN2 37
  • 70 (a)
ManyToMany
SPIN3 36
  • 92.25 (n)
  • 89.06 (a)
dog
(Canis familiaris)
Mammalia SPIN3 37
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm21637 37
  • 56 (a)
ManyToMany
Spin3 16
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 84 (a)
OneToMany
chicken
(Gallus gallus)
Aves SPINW 37
  • 75 (a)
ManyToMany
SPINZ 37
  • 83 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 84 (a)
OneToMany
Species with no ortholog for SPIN3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPIN3 Gene

ENSEMBL:
Gene Tree for SPIN3 (if available)
TreeFam:
Gene Tree for SPIN3 (if available)

Paralogs for SPIN3 Gene

Paralogs for SPIN3 Gene

Selected SIMAP similar genes for SPIN3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPIN3: view

Variants for SPIN3 Gene

Sequence variations from dbSNP and Humsavar for SPIN3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs912956 -- 56,983,705(+) TTCAA(C/T)AGACC intron-variant
rs1132982 -- 56,994,356(-) CTCCA(A/G)CAGAA frameshift-variant, reference, intron-variant
rs1325856 -- 56,993,682(+) TAGAA(C/T)TGAGA utr-variant-3-prime, intron-variant
rs1325857 -- 56,981,334(+) ccagt(A/C)tggga intron-variant
rs1853866 -- 56,981,266(+) ggctg(A/T)gacag intron-variant

Relevant External Links for SPIN3 Gene

HapMap Linkage Disequilibrium report
SPIN3

No data available for Structural Variations from Database of Genomic Variants (DGV) for SPIN3 Gene

Disorders for SPIN3 Gene

No disorders were found for SPIN3 Gene.

No data available for UniProtKB/Swiss-Prot for SPIN3 Gene

Publications for SPIN3 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (PMID: 17620599) Xiao K. … Lefkowitz R.J. (Proc. Natl. Acad. Sci. U.S.A. 2007) 3

Products for SPIN3 Gene

Sources for SPIN3 Gene

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