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SPIN2A Gene

protein-coding   GIFtS: 45
GCID: GC0XM057178

Spindlin Family, Member 2A

(Previous names: spindlin family, member 2)
(Previous symbol: SPIN2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Spindlin Family, Member 2A1 2     Spindlin Homolog 22
SPIN21 2 3     spindlin-2A2
Spindlin-Like Protein 2A2 3     Spindlin-Like Protein 22
DXF342 3     SPIN-23
Spindlin Family, Member 21     SPIN-2A3
Centromeric Spin2 Copy2     Protein DXF343
dJ323P24.12     DSF345

External Ids:    HGNC: 206941   Entrez Gene: 544662   Ensembl: ENSG000001470597   OMIM: 3006215   UniProtKB: Q998653   

Export aliases for SPIN2A gene to outside databases

Previous GC identifer: GC0XM054225


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SPIN2A Gene:
This gene encodes one of three members of the DXF34 gene family, located in a 100-kb region of chromosome Xp11.21.
(provided by RefSeq, Nov 2009)

GeneCards Summary for SPIN2A Gene:
SPIN2A (spindlin family, member 2A) is a protein-coding gene. Diseases associated with SPIN2A include hiv-1, and mental retardation. An important paralog of this gene is SPIN2B.

UniProtKB/Swiss-Prot: SPI2A_HUMAN, Q99865
Function: May be involved in the regulation of cell cycle progression (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011630.15  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SPIN2A gene promoter:
         SRF   GR   USF1   HOXA3   USF-1   GR-beta   SRF (504 AA)   GR-alpha   FOXL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SPIN2A promoter sequence
   Search Chromatin IP Primers for SPIN2A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPIN2A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.1   Ensembl cytogenetic band:  Xp11.21   HGNC cytogenetic band: Xp11.1

SPIN2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPIN2A gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM057178:  view genomic region     (about GC identifiers)

Start:
57,160,963 bp from pter      End:
57,164,058 bp from pter
Size:
3,096 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SPI2A_HUMAN, Q99865 (See protein sequence)
Recommended Name: Spindlin-2A  
Size: 258 amino acids; 29188 Da
Sequence caution: Sequence=CAA70988.1; Type=Frameshift; Positions=10;
Secondary accessions: O75650 Q6IPW2 Q9UJJ0

Explore the universe of human proteins at neXtProt for SPIN2A: NX_Q99865

Explore proteomics data for SPIN2A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys108

  • See SPIN2A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061876.3  
    ENSEMBL proteins: 
     ENSP00000364043   ENSP00000364041  

    SPIN2A Human Recombinant Protein Products:

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    Novus Biologicals SPIN2A Protein
    Novus Biologicals SPIN2A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    SPIN2A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Browse Antibodies at Cloud-Clone Corp.
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    LSBio Antibodies in human, mouse, rat for SPIN2A

    SPIN2A Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR003671 Spin_Ssty

    Graphical View of Domain Structure for InterPro Entry Q99865

    ProtoNet protein and cluster: Q99865

    1 Blocks protein domain: IPB003671 Spindlin/spermiogenesis-specific protein

    UniProtKB/Swiss-Prot: SPI2A_HUMAN, Q99865
    Similarity: Belongs to the SPIN/STSY family


    SPIN2A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SPI2A_HUMAN, Q99865
    Function: May be involved in the regulation of cell cycle progression (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    SPIN2A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SPIN2A:
     Increased cell death in breast 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPIN2A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SPIN2A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SPIN2A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SPIN2A

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SPIN2A using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate SPIN2A:
    hsa-miR-3149 hsa-miR-3618 hsa-miR-934 hsa-miR-1283 hsa-miR-3692
    SwitchGear 3'UTR luciferase reporter plasmidSPIN2A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SPIN2A
    Predesigned siRNA for gene silencing in human, mouse, rat SPIN2A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SPIN2A

    Clone
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    OriGene clones in human, mouse for SPIN2A (see all 7)
    OriGene ORF clones in mouse, rat for SPIN2A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SPIN2A (NM_019003)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPIN2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPIN2A

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for SPIN2A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPIN2A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    peroxisome2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    SPIN2A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SPIN2A
    Interactions:

        Search GeneGlobe Interaction Network for SPIN2A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SPIN2A (ENSP000003640414) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle IEA--
    GO:0007276gamete generation IEA--

    SPIN2A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SPIN2A (SPI2A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SPIN2A gene: 
    NM_019003.3  

    Unigene Cluster for SPIN2A:

    Spindlin family, member 2A
    Hs.460725  [show with all ESTs]
    Unigene Representative Sequence: BC071694
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374908(uc022bxx.1) ENST00000374906(uc004dvb.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SPIN2A using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate SPIN2A:
    hsa-miR-3149 hsa-miR-3618 hsa-miR-934 hsa-miR-1283 hsa-miR-3692
    SwitchGear 3'UTR luciferase reporter plasmidSPIN2A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SPIN2A
    Predesigned siRNA for gene silencing in human, mouse, rat SPIN2A
    Clone
    Products:
         
    OriGene clones in human, mouse for SPIN2A (see all 7)
    OriGene ORF clones in mouse, rat for SPIN2A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SPIN2A (NM_019003)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPIN2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPIN2A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SPIN2A
    OriGene qSTAR qPCR primer pairs in human, mouse for SPIN2A
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SPIN2A
      QuantiTect SYBR Green Assays in human, mouse, rat SPIN2A
      QuantiFast Probe-based Assays in human, mouse, rat SPIN2A

    Additional mRNA sequence: BC071694.1 

    4 DOTS entries:

    DT.100755465  DT.75165080  DT.100803394  DT.310824 

    13 AceView cDNA sequences:

    BU625654 BM973025 Y09858 NM_019003 BI523896 BX279774 BC071694 CD652258 
    BI524653 BQ686850 BQ687902 BE731164 BQ889251 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SPIN2A    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c ^ 3a · 3b · 3c
    SP1:                          -     -           -     -                     
    SP2:                                -                                       
    SP3:                          -     -                                       
    SP4:                          -     -                                       
    SP5:                                                                        


    ECgene alternative splicing isoforms for SPIN2A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SPIN2A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SPIN2A Expression
    About this image

    SPIN2A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SPIN2A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.460725
        Custom PCR Arrays for SPIN2A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPIN2A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SPIN2A gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spin25
    Gm37571
    spindlin family, member 25
    predicted pseudogene 37571
    73.15(n)1
    66.06(a)1
      X (72.38 cM)5
    1000422671  XM_006527550.11  XP_006527613.11 
     1538322255 
    chicken
    (Gallus gallus)
    Aves SPINZ6
    SPINW6
    Gallus gallus spindlin 1 (SPINW), mRNA.
    77(a)
    70(a)
    many ↔ many
    many ↔ many
    Z(43031150-43106716)
    JH375233.1(93400-104628)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    77(a)
    1 → many
    2(37159109-37173005)


    ENSEMBL Gene Tree for SPIN2A (if available)
    TreeFam Gene Tree for SPIN2A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SPIN2A gene
    SPIN2B1 2  SPIN12  SPIN42  SPIN32  
    4 SIMAP similar genes for SPIN2A using alignment to 1 protein entry:     SPI2A_HUMAN:
    SPIN3    SPIN1    SPIN4    SPIN2B

    SPIN2A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SPIN2A (see all 63)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1405324101,2
    --57173427(+) TTTCCC/TCTAAG 1 -- int10--------
    rs1850981361,2
    --57173492(+) TCTCAA/TAGGTC 1 -- int10--------
    rs1879986391,2
    --57173531(+) TCTGGC/TCCTTT 1 -- int10--------
    rs9096541,2
    C,H--57173548(-) GCTTAG/AGAAGA 1 -- int1 ese310Minor allele frequency- A:0.00NA EA MN NS 860
    rs59025631,2
    C--57173605(+) CCCTG-/CCCCCC 1 -- int10--------
    rs1504618051,2
    C--57173616(+) TCCAGA/TCCAGA 1 -- int10--------
    rs1381996261,2
    --57173686(+) ACAGCC/TGAAAT 1 -- int10--------
    rs736262571,2
    C,F--57173703(+) CTGTTA/CGTTCC 1 -- int11Minor allele frequency- C:0.00WA 2
    rs1824528271,2
    --57173831(+) GCAAAA/GATGTT 1 -- ut310--------
    rs20202261,2
    C,F--57173967(-) GTCTAC/TGATTT 2 Y syn1 ese31Minor allele frequency- T:0.01NA 4506

    HapMap Linkage Disequilibrium report for SPIN2A (57160963 - 57164058 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SPIN2A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv483129CNV Loss15286789

    Locus Specific Mutation Databases (LSDB): SPIN2A

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SPIN2A
    DNA2.0 Custom Variant and Variant Library Synthesis for SPIN2A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300621    OMIM disorders: --

    3 diseases for SPIN2A:    
    About MalaCards
    hiv-1    mental retardation    retinitis


    SPIN2A for disorders           About GeneDecksing


    Export disorders for SPIN2A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SPIN2A gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with SPIN2A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The structure of DXF34, a human X-linked sequence family with homology to a transcribed mouse Y-linked repeat. (PubMed id 9271673)1, 2, 3 Laval S.H.... Boyd Y. (Mamm. Genome 1997)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. (PubMed id 23084401)1 Singh G....Moore M.J. (Cell 2012)
    5. A catalogue of putative HIV-1 protease host cell substrates. (PubMed id 22944692)1 Impens F....Gevaert K. (Biol. Chem. 2012)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. (PubMed id 19377476)1 Tarpey P.S.... Stratton M.R. (Nat. Genet. 2009)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54466 HGNC: 20694 AceView: SPIN2 Ensembl:ENSG00000147059 euGenes: HUgn54466
    ECgene: SPIN2A H-InvDB: SPIN2A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SPIN2A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SPIN2A gene:
    Search GeneIP for patents involving SPIN2A

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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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