Aliases for SPIC Gene
External Ids for SPIC Gene
GeneCards Summary for SPIC Gene
SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related)) is a Protein Coding gene. Diseases associated with SPIC include wolman disease and lipomatosis. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is SPI1.
UniProtKB/Swiss-Prot for SPIC Gene
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5-GAGGA[AT]-3) that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity).