Aliases for SPI1 Gene
Aliases for SPI1 Gene
External Ids for SPI1 Gene
- HGNC: 11241
- Entrez Gene: 6688
- Ensembl: ENSG00000066336
- OMIM: 165170
- UniProtKB: P17947
Previous GeneCards Identifiers for SPI1 Gene
- GC11M049316
- GC11M048254
- GC11M047408
- GC11M047340
- GC11M047332
- GC11M047075
- GC11M047430
- GC11M048075
- GC11M048800
- GC11M049902
- GC11M047546
- GC11M047947
- GC11M050799
- GC11M051594
- GC11M052256
Summaries for SPI1 Gene
-
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for SPI1 Gene
SPI1 (Spi-1 Proto-Oncogene) is a Protein Coding gene. Diseases associated with SPI1 include Inflammatory Diarrhea and Interdigitating Dendritic Cell Sarcoma. Among its related pathways are Validated targets of C-MYC transcriptional repression and C-MYB transcription factor network. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA binding. An important paralog of this gene is SPIB.
UniProtKB/Swiss-Prot for SPI1 Gene
-
Binds to the PU-box, a purine-rich DNA sequence (5-GAGGAA-3) that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPI1 Gene
Genomics for SPI1 Gene
Regulatory Elements for SPI1 Gene
Enhancers for SPI1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around SPI1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the SPI1 gene promoter:
Regulatory Element Products
Genomic Location for SPI1 Gene
- Chromosome:
- 11
- Start:
- 47,354,858 bp from pter
- End:
- 47,395,640 bp from pter
- Size:
- 40,783 bases
- Orientation:
- Minus strand
Genomic View for SPI1 Gene
Genes around SPI1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p11.2 by Ensembl
- 11p11.2 by Entrez Gene
- 11p11.2 by HGNC
SPI1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SPI1 Gene
Proteins for SPI1 Gene
-
Protein details for SPI1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P17947-SPI1_HUMAN
- Recommended name:
- Transcription factor PU.1
- Protein Accession:
- P17947
Protein attributes for SPI1 Gene
- Size:
- 270 amino acids
- Molecular mass:
- 31083 Da
- Quaternary structure:
-
- Binds DNA as a monomer. Interacts with CEBPD and NONO (By similarity). Interacts with RUNX1 and SPIB. Interacts with GFI1; the interaction represses SPI1 transcriptional activity.
- SequenceCaution:
-
- Sequence=CAA36281.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for SPI1 Gene
Post-translational modifications for SPI1 Gene
Other Protein References for SPI1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for SPI1
- R&D Systems Antibodies for SPI1 (PU.1/Spi-1)
- Cell Signaling Technology (CST) Antibodies for SPI1 (PU.1)
-
Custom Antibody ServicesOriGene Antibodies for SPI1
- Novus Biologicals Antibodies for SPI1
- Invitrogen Antibodies for SPI1
- antibodies-online Antibodies for SPI1: See all 133
- GeneTex SPI1 antibody for SPI1
-
Santa Cruz Biotechnology (SCBT) Antibodies for SPI1
Protein Products
-
OriGene Purified Proteins for SPI1
- Search Origene for MassSpec and Protein Over-expression Lysates for SPI1
- Origene Custom Protein Services for SPI1
- antibodies-online Proteins for SPI1: See all 11
- Search antibodies-online for peptides
- Search GeneTex for Proteins for SPI1
Assay Products
- antibodies-online Kits for SPI1: See all 7
No data available for DME Specific Peptides for SPI1 Gene
Domains & Families for SPI1 Gene
Gene Families for SPI1 Gene
Protein Domains for SPI1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SPI1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P17947- Family:
-
- Belongs to the ETS family.
Function for SPI1 Gene
Molecular function for SPI1 Gene
- GENATLAS Biochemistry:
- spleen focus forming virus (SFFV) proviral integration oncogene spi1,Pu-1 homolog,expressed in various hemapoietic cell lines,required for the development of both myeloid and lymphoid lineages
- UniProtKB/Swiss-Prot Function:
- Binds to the PU-box, a purine-rich DNA sequence (5-GAGGAA-3) that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity).
- UniProtKB/Swiss-Prot Induction:
- Highly expressed in both FV-P and FV-A-induced erythro-leukemia cell lines that have undergone rearrangements of the SPI1 gene due to the insertion of SFFV. Negatively regulated by microRNA-155 (miR-155).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | IEA | -- |
| GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | IEA | -- |
| GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | ISS,IEA | -- |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | IBA | -- |
| GO:0000982 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | IEA | -- |
Phenotypes for SPI1 Gene
- MGI mutant phenotypes for SPI1:
-
inferred from 18 alleles
- mortality/aging
- cellular phenotype
- normal phenotype
- growth/size/body region phenotype
- immune system phenotype
- nervous system phenotype
- homeostasis/metabolism phenotype
- neoplasm
- endocrine/exocrine gland phenotype
- vision/eye phenotype
- skeleton phenotype
- hematopoietic system phenotype
- liver/biliary system phenotype
- craniofacial phenotype
- no phenotypic analysis
- GenomeRNAi human phenotypes for SPI1:
-
- Increased viability
- Negative genetic interaction between MUS81-/- and MUS81+/+
- Decreased viability ratio
- Decreased shRNA abundance (Z-score < -2)
- Decreased NF-kappaB reporter expression
- Decreased POU5F1-GFP protein expression
- Increased shRNA abundance (Z-score > 2)
- Decreased OCT4 protein expression
- Decreased NANOG protein expression
Animal Models for SPI1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SPI1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SPI1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SPI1 gene
- Search ViGene Biosciences for SPI1
CRISPR Products
-
OriGene CRISPR knockouts for SPI1
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPI1
- GenScript: Design CRISPR guide RNA sequences for SPI1
miRNA for SPI1 Gene
- miRTarBase miRNAs that target SPI1
-
- hsa-mir-155-5p (MIRT004282)
- hsa-mir-569 (MIRT004827)
- hsa-mir-34a-5p (MIRT005724)
- hsa-mir-424-5p (MIRT005928)
- hsa-mir-9-5p (MIRT021410)
- hsa-mir-296-3p (MIRT038360)
- bta-mir-155 (MIRT053953)
- hsa-mir-6845-3p (MIRT625713)
- hsa-mir-6749-3p (MIRT625714)
- hsa-mir-4669 (MIRT625715)
- hsa-mir-3657 (MIRT625716)
- hsa-mir-6090 (MIRT625717)
- hsa-mir-7113-3p (MIRT625718)
- hsa-mir-339-5p (MIRT625719)
- hsa-mir-1247-3p (MIRT625720)
- hsa-mir-5587-3p (MIRT625721)
Targeted motifs for SPI1 Gene
HOMER Transcription Factor Regulatory Elements motif SPI1
- Consensus sequence: AGAGGAAGTG Submotif: canonical Cell Type: ThioMac GEO ID: GSE21512
miRNA Products
- Search ViGene Biosciences for SPI1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for SPI1
- Browse OriGene Inhibitory RNA Products For SPI1
-
ViGene Biosciences ready-to-package AAV shRNAs for SPI1 gene
Clone Products
- Sino Biological Human cDNA Clone for SPI1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SPI1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPI1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for SPI1
-
ViGene Biosciences adenoviral particle packaged cDNA for SPI1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SPI1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SPI1 gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA4-13815) for SPI1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology and Transcription Factor Targets for SPI1 Gene
Localization for SPI1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SPI1 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | IDA | 15304486 |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for SPI1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Endometrial cancer | ||
| 2 | Epstein-Barr virus infection | ||
| 3 | HTLV-I infection | ||
| 4 | Osteoclast differentiation | ||
| 5 | Pathways in cancer | ||
Pathways by source for SPI1 Gene
1 Cell Signaling Technology pathway for SPI1 Gene
9 BioSystems pathways for SPI1 Gene
6 KEGG pathways for SPI1 Gene
1 GeneGo (Thomson Reuters) pathway for SPI1 Gene
Interacting Proteins for SPI1 Gene
Selected Interacting proteins:
ENSP00000227163
P17947-SPI1_HUMAN
for SPI1 Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | IEA | -- |
| GO:0001944 | vasculature development | IEA | -- |
| GO:0002320 | lymphoid progenitor cell differentiation | IEA | -- |
| GO:0002573 | myeloid leukocyte differentiation | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
No data available for SIGNOR curated interactions for SPI1 Gene
Transcripts for SPI1 Gene
mRNA/cDNA for SPI1 Gene
- (4) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (114) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SPI1 Gene
- Spleen focus forming virus (SFFV) proviral integration oncogene spi1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for SPI1
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPI1
- GenScript: Design CRISPR guide RNA sequences for SPI1
miRNA Products
- Search ViGene Biosciences for SPI1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for SPI1
- Browse OriGene Inhibitory RNA Products For SPI1
-
ViGene Biosciences ready-to-package AAV shRNAs for SPI1 gene
Clone Products
- Sino Biological Human cDNA Clone for SPI1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SPI1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPI1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA4-13815) for SPI1
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||
| SP2: | |||||||||||||||||||
| SP3: | - | - |
Expression for SPI1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Small Pre B-Cells Hematopoietic Bone Marrow
- Pro B-Cells Hematopoietic Bone Marrow
- Granulocytes Peripheral Blood
- Osteoclast Precursor Cells Hematopoietic Bone Marrow
- B-cell Progenitor Cells Peripheral Blood
-
Kidney (Urinary System)
- Cortical Stroma Cells Interstitial Stroma
- Medullary Stroma Cells Interstitial Stroma
- Glomerulus
- Glomerular Tuft
- Interstitial Stroma
-
Bone (Muscoskeletal System)
- Osteoclast Precursor Cells Hematopoietic Bone Marrow
- Mononucleated Osteoclasts Bone Marrow
- Bone Marrow
-
Spleen (Hematopoietic System)
-
Lung (Respiratory System)
mRNA differential expression in normal tissues according to GTEx for SPI1 Gene
This gene is overexpressed in Whole Blood (x39.7).
This gene is overexpressed in Monocytes (25.8), Blymphocyte (24.0), and Pancreas (12.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SPI1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SPI1 Gene:
SPI1SOURCE GeneReport for Unigene cluster for SPI1 Gene:
Hs.502511Evidence on tissue expression from TISSUES for SPI1 Gene
- Liver(4.4)
- Blood(3.3)
- Bone marrow(3.3)
- Spleen(3.1)
- Intestine(2.9)
- Lymph node(2.8)
- Lung(2.5)
Primer Products
-
OriGene qPCR primer pairs for SPI1
-
OriGene qPCR primer pairs and template standards for SPI1
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPI1 Gene
Orthologs for SPI1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | SPI1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | SPI1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Spi1 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Spi1 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | SPI1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SPI1 35 |
|
OneToOne | |
| chimpanzee (Pan troglodytes) |
Mammalia | SPI1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | SPI1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | SPI1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | spi1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | spi1b 34 35 |
|
||
| spi1 34 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10886 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for SPI1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for SPI1 Gene
(2) SIMAP similar genes for SPI1 Gene using alignment to 3 proteins:
Variants for SPI1 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000024728 | -- | 47,397,627(+) | AGTGG(A/G)TCACC | upstream-variant-2KB | |
| rs1000055357 | -- | 47,372,801(+) | CCTCG(C/G)TGAAT | intron-variant | |
| rs1000118259 | -- | 47,391,929(+) | GGGCA(A/G)GGCAG | intron-variant | |
| rs1000303349 | -- | 47,356,961(+) | ACACA(C/T)GCTCA | intron-variant | |
| rs1000342945 | -- | 47,397,318(+) | AACCT(G/T)AGAGG | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv622e59 | CNV | duplication | 20981092 |
| esv275512 | CNV | loss | 21479260 |
| esv3439899 | CNV | duplication | 20981092 |
| esv992404 | CNV | insertion | 20482838 |
| nsv1075832 | CNV | duplication | 25765185 |
| nsv1127180 | CNV | deletion | 24896259 |
| nsv1132343 | CNV | duplication | 24896259 |
| nsv1134113 | CNV | deletion | 24896259 |
| nsv1141192 | CNV | duplication | 24896259 |
| nsv509404 | CNV | insertion | 20534489 |
| nsv513315 | CNV | insertion | 21212237 |
| nsv554210 | CNV | loss | 21841781 |
| nsv825871 | CNV | gain | 20364138 |
| nsv832141 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
40.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.34;
26.47% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for SPI1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPI1 Gene
Disorders for SPI1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| inflammatory diarrhea |
|
|
| interdigitating dendritic cell sarcoma |
|
|
| parotid gland cancer |
|
|
| acute erythroid leukemia |
|
|
| histiocytic and dendritic cell cancer |
|
|
Search SPI1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for SPI1
No data available for UniProtKB/Swiss-Prot and Genatlas for SPI1 Gene
Publications for SPI1 Gene
- The human homologue of the putative proto-oncogene Spi-1: characterization and expression in tumors. (PMID: 1693183) Ray D. … Moreau-Gachelin F. (Oncogene 1990) 2 3 4 22 64
- Vav1 and PU.1 are recruited to the CD11b promoter in APL-derived promyelocytes: role of Vav1 in modulating PU.1-containing complexes during ATRA-induced differentiation. (PMID: 19747912) Brugnoli F. … Bertagnolo V. (Exp. Cell Res. 2010) 3 22 64
- Heterozygous deletion of the PU.1 locus in human AML. (PMID: 19890096) Bonadies N. … Mueller B.U. (Blood 2010) 3 46 64
- Physical and functional interactions between hematopoietic cell-specific ETS transcription factors and homeodomain proteins. (PMID: 18692240) Yamada T. … Tsuchida S. (Leuk. Res. 2009) 3 22 64
- Roles of PU.1 in monocyte- and mast cell-specific gene regulation: PU.1 transactivates CIITA pIV in cooperation with IFN-gamma. (PMID: 19502584) Ito T. … Okumura K. (Int. Immunol. 2009) 3 22 64
Products for SPI1 Gene
- R&D Systems Antibodies for SPI1 (PU.1/Spi-1)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for SPI1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SPI1
- Search Origene for MassSpec and Protein Over-expression Lysates for SPI1
- Origene Custom Protein Services for SPI1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for SPI1
- Browse OriGene Inhibitory RNA Products For SPI1
- OriGene qPCR primer pairs and template standards for SPI1
- OriGene qPCR primer pairs for SPI1
- OriGene CRISPR knockouts for SPI1
- OriGene ORF clones in human for SPI1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SPI1
- GenScript: Next-day shipping cDNA ORF clone for SPI1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for SPI1
- GenScript Custom Assay Services for SPI1
- GenScript Custom overexpressing Cell Line Services for SPI1
- GenScript: Design CRISPR guide RNA sequences for SPI1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for SPI1
- Cell Signaling Technology (CST) Antibodies for SPI1 (PU.1)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for SPI1
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for SPI1
- Novus Biologicals proteins and lysates for SPI1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for SPI1: See all 133
- antibodies-online Kits for SPI1: See all 7
- antibodies-online Proteins for SPI1: See all 11
- Search antibodies-online for peptides
- GeneTex SPI1 antibody for SPI1
- Search GeneTex for Proteins for SPI1
- ViGene Biosciences adenoviral particle packaged cDNA for SPI1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for SPI1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for SPI1 gene
- Search ViGene Biosciences for SPI1
- Santa Cruz Biotechnology (SCBT) Antibodies for SPI1
- Search Santa Cruz Biotechnology (SCBT) for SPI1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SPI1
- Horizon Cell Lines for SPI1
- Cyagen custom Knockout/knockin (KOKI) mouse models for SPI1
- VectorBuilder custom plasmid, inducible vectors for SPI1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPI1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for SPI1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
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