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Aliases for SPHAR Gene

Aliases for SPHAR Gene

  • S-Phase Response (Cyclin Related) 2 3 5
  • S-Phase Response Protein 4

External Ids for SPHAR Gene

Previous GeneCards Identifiers for SPHAR Gene

  • GC01P227887
  • GC01M225134
  • GC01P225840
  • GC01P226401
  • GC01P225748
  • GC01P227506
  • GC01P229440
  • GC01P199930

Summaries for SPHAR Gene

GeneCards Summary for SPHAR Gene

SPHAR (S-Phase Response (Cyclin Related)) is a Protein Coding gene. Among its related pathways are Insulin Signaling.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPHAR Gene

Genomics for SPHAR Gene

Regulatory Elements for SPHAR Gene

Enhancers for SPHAR Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SPHAR on UCSC Golden Path with GeneCards custom track

Genomic Location for SPHAR Gene

229,304,382 bp from pter
229,305,504 bp from pter
1,123 bases
Plus strand

Genomic View for SPHAR Gene

Genes around SPHAR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPHAR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPHAR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPHAR Gene

Proteins for SPHAR Gene

  • Protein details for SPHAR Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein SPHAR
    Protein Accession:
    Secondary Accessions:
    • Q4EW09
    • Q6NSB9

    Protein attributes for SPHAR Gene

    63 amino acids
    Molecular mass:
    7515 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPHAR Gene

Proteomics data for SPHAR Gene at MOPED

Post-translational modifications for SPHAR Gene

No Post-translational modifications

Other Protein References for SPHAR Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPHAR Gene

Domains & Families for SPHAR Gene

Protein Domains for SPHAR Gene


Suggested Antigen Peptide Sequences for SPHAR Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPHAR: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SPHAR Gene

Function for SPHAR Gene

genes like me logo Genes that share phenotypes with SPHAR: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SPHAR Gene

Localization for SPHAR Gene

Subcellular locations from

Jensen Localization Image for SPHAR Gene COMPARTMENTS Subcellular localization image for SPHAR gene
Compartment Confidence
extracellular 3
cytosol 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SPHAR Gene

Pathways & Interactions for SPHAR Gene

SuperPathways for SPHAR Gene

Superpath Contained pathways
1 Insulin Signaling
genes like me logo Genes that share pathways with SPHAR: view

Pathways by source for SPHAR Gene

1 BioSystems pathway for SPHAR Gene

Interacting Proteins for SPHAR Gene

Gene Ontology (GO) - Biological Process for SPHAR Gene


No data available for SIGNOR curated interactions for SPHAR Gene

Drugs & Compounds for SPHAR Gene

No Compound Related Data Available

Transcripts for SPHAR Gene

mRNA/cDNA for SPHAR Gene

(1) REFSEQ mRNAs :
(226) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SPHAR Gene

No ASD Table

Relevant External Links for SPHAR Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPHAR Gene

mRNA expression in normal human tissues for SPHAR Gene

genes like me logo Genes that share expression patterns with SPHAR: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPHAR Gene

Orthologs for SPHAR Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for SPHAR Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SPHAR 35
  • 98.94 (n)
  • 96.83 (a)
Species with no ortholog for SPHAR:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPHAR Gene

Gene Tree for SPHAR (if available)
Gene Tree for SPHAR (if available)

Paralogs for SPHAR Gene Pseudogenes for SPHAR Gene

genes like me logo Genes that share paralogs with SPHAR: view

No data available for Paralogs for SPHAR Gene

Variants for SPHAR Gene

Variation tolerance for SPHAR Gene

Residual Variation Intolerance Score: 65.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.01; 0.33% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SPHAR Gene

Disorders for SPHAR Gene

Relevant External Links for SPHAR

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPHAR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPHAR Gene

Publications for SPHAR Gene

  1. Irreversible repression of DNA synthesis in Fanconi anemia cells is alleviated by the product of a novel cyclin-related gene. (PMID: 7799938) Digweed M. … Sperling K. (Mol. Cell. Biol. 1995) 2 3 4 67
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SPHAR Gene

Sources for SPHAR Gene