SPG20 Gene
protein-coding GIFtS: 54
GCID: GC13M036875
|
|
spastic paraplegia 20 (Troyer syndrome)
| |
Aliases
for SPG20 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Spastic Paraplegia 20 (Troyer Syndrome)1 2 | | SPARTIN2 | | TAHCCP11 2 3 | | Spartin1 | | KIAA06101 3 | | Spastic Paraplegia 20 Protein3 | | Trans-Activated By Hepatitis C Virus Core Protein 12 3 | | |
Export aliases for SPG20 gene to outside databasesPrevious GC identifers: GC13M030863 GC13M035813 GC13M034675 GC13M034673 GC13M035773 GC13M017687 |
Summaries
for SPG20 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SPG20:
This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and isimplicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria andpartially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in proteintranslocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking ofEGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutationsassociated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). (provided by RefSeq, Nov2008)
UniProtKB/Swiss-Prot: SPG20_HUMAN, Q8N0X7Function: May be implicated in endosomal trafficking, or microtubule dynamics, or both
Gene Wiki entry for SPG20
|
Genomic Views
for SPG20 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SPG20 gene promoter:
AREB6 Pbx1a p53 Hand1 CUTL1 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for SPG20
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPG20 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q13.3 Ensembl cytogenetic band: 13q13.3 HGNC cytogenetic band: 13q13.1SPG20 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13M036875: view genomic region
(about GC identifiers)
Start:
|
36,875,775 bp from pter |
End:
|
36,944,317 bp from pter |
Size:
|
68,543 bases |
Orientation:
|
minus strand |
|
Proteins
for SPG20 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SPG20_HUMAN, Q8N0X7 (See
protein sequence)Recommended Name: Spartin Size: 666 amino acids; 72833 Da
Subunit: Interacts with ITCH and WWP1
Subcellular location: Cytoplasm. Note=Transiently associated with endosomes
Sequence caution: Sequence=BAA25536.1; Type=Erroneous initiation; Sequence=CAC17479.1; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for SPG20:2DL1 (3D)
Secondary accessions: O60349 Q86Y67 Q9H1T2 Q9H1T3Explore the universe of human proteins at neXtProt for SPG20: NX_Q8N0X7
Post-translational modifications:
Ubiquitinated; ubiquitination does not require ITCH and WWP11
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N0X7
SPG20 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001135766.1 NP_001135767.1 NP_001135768.1 NP_055902.1
ENSEMBL proteins: ENSP00000406061 ENSP00000347314 ENSP00000414147 ENSP00000416434
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
SPG20 for ontologies About GeneDecksing
SPG20 Antibody Products:
Assay Products for SPG20: |
Protein
Domains /
Families
for SPG20 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SPG20 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N0X7ProtoNet protein and cluster: Q8N0X7 UniProtKB/Swiss-Prot: SPG20_HUMAN, Q8N0X7Similarity: Contains 1 MIT domain |
Function
for SPG20 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SPG20_HUMAN, Q8N0X7Function: May be implicated in endosomal trafficking, or microtubule dynamics, or both
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPG20 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPG20 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for SPG20 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPG20 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPG20 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SPG20 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SPG20:
Animal Models:
Mouse knock-out Spg20tm1.1Xen for SPG20
7 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Spg20):
SPG20 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SPG20 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SPG20
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/30 Interacting proteins for SPG20 (Q8N0X72, 3 ENSP000003473144) via UniProtKB, MINT, STRING, and/or I2D (see all 30)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
SPG20 for ontologies About GeneDecksing
|
Drugs & Compounds
for SPG20 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SPG20
Search CenterWatch for drugs/clinical trials and news about SPG20
|
Transcripts
for SPG20 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SPG20 gene (4 alternative transcripts): NM_001142294.1 NM_001142295.1 NM_001142296.1 NM_015087.4 Unigene Cluster for SPG20: Spastic paraplegia 20 (Troyer syndrome) Hs.440414 [show with all ESTs]Unigene Representative Sequence: NM_01508714 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000438666(uc010ten.2) ENST00000494062 ENST00000491805 ENST00000460126
ENST00000475603 ENST00000482146 ENST00000480300 ENST00000495510(uc001uvp.2)
ENST00000495783 ENST00000494703 ENST00000476377 ENST00000355182(uc001uvq.3)
ENST00000451493(uc001uvo.3) ENST00000423217(uc001uvn.3 uc001uvm.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPG20 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPG20 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): SPG20 (NM_001142294) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPG20 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPG20 |
Additional cDNA sequence: AB011182.1 AK001949.1 AK002207.1 AK057764.1 AK291724.1 AK302119.1 AY038359.1 AY123329.1 BC026284.1 BC047083.1 BX648004.1 17 DOTS entries: DT.317189 DT.97836680 DT.120778713 DT.95300476 DT.100747270 DT.75138480 DT.95183638 DT.100747269 DT.101964796 DT.75122650 DT.97787683 DT.95300472 DT.100689110 DT.40223736 DT.95300473 DT.95309279 DT.97777339 24/246 AceView cDNA sequences (see all 246): BX113951 BG571910 AI378653 BX498854 BI752765 AL597590 BM710803 BG575494 AU136898 CR609925 BM456959 AA419376 AI638619 CK299727 AL702201 AU133175 AL118692 BP351316 BP340079 BC026284 AU141085 AI471967 AK001949 BP379493
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for SPG20 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f | · | 6g | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · |
|---|
|
| SP1: | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP5: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c |
|---|
|
| SP1: | | | - | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | | | | | |
| SP4: | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SPG20
|
Expression
for SPG20 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SPG20 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTGTATTGT
About this image
See SPG20 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SPG20
SOURCE GeneReport for Unigene cluster: Hs.440414
UniProtKB/Swiss-Prot: SPG20_HUMAN, Q8N0X7Tissue specificity: Ubiquitously expressed, with highest levels of expression detected in adipose tissue
SABiosciences Custom PCR Arrays for SPG20
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPG20
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPG20 |
Orthologs
for SPG20 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SPG20 gene from 6/16 species (see all 16) About this table
ENSEMBL Gene Tree for SPG20 (if available)
TreeFam Gene Tree for SPG20 (if available) |
Paralogs
for SPG20 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SPG20 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SPG20 (36875775 - 36944317 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SPG20: --
Human Gene Mutation Database (HGMD): SPG20
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPG20 |
|
Disorders
/ Diseases
for SPG20 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SPG20 for disorders About GeneDecksing
OMIM gene information: 607111
OMIM disorders: 275900
UniProtKB/Swiss-Prot: SPG20_HUMAN, Q8N0X7
Defects in SPG20 are the cause of spastic paraplegia autosomal recessive type 20 (SPG20) [MIM:275900]; alsoknown as Troyer syndrome (TRS). Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual,progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quitevariable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, anddragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, orthe weakness and stiffness may spread to other parts of the body. SPG20 is characterized by dysarthria, distalamyotrophy, mild developmental delay and short stature
15  diseases for SPG20: About MalaCardsspastic paraplegia 20 spastic paraplegia troyer syndrome paraplegia
spasticity hepatitis c pseudobulbar palsy hereditary spastic paraplegia
hepatitis corpus callosum short stature motor neuron disease
multiple sclerosis neuropathy neuronitis
1 disease from the University of Copenhagen DISEASES database for SPG20:Paraplegia 3 Novoseek disease relationships for SPG20 gene About this table
GeneTests: SPG20
Troyer Syndrome
Human Genome Epidemiology (HuGE) Navigator: SPG20 (1 document)
Export disorders for SPG20 gene to outside databases
|
Publications
for SPG20 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SPG20 gene, integrated from 9 sources (see all 47):
(articles sorted by number of sources associating them with SPG20) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- SPG20 is mutated in Troyer syndrome, an hereditary spastic paraplegia. (PubMed id 12134148)1, 2, 3, 9 Patel H....Crosby A.H. (2002)
- Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5. (PubMed id 19580544)1, 2, 9 Edwards T.L....Reid E. (2009)
- The identification of a conserved domain in both spartin and spastin, mutated in hereditary spastic paraplegia. (PubMed id 12676568)1, 2, 9 Ciccarelli F.D.... Crosby A.H. (2003)
- Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1, 2 Meierhofer D.... Kaiser P. (2008)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2 Nagase T....Ohara O. (1998)
- The Troyer syndrome. A recessive form of spastic paraplegia with distal muscle wasting. (PubMed id 6022528)1, 3 Cross H.E. and McKusick V.A. (1967)
- A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover. (PubMed id 19307600)1, 9 Eastman S.W....Bieniasz P.D. (2009)
- Identification of novel spartin-interactors shows spa rtin is a multifunctional protein. (PubMed id 19765186)1, 9 Milewska M....Byrne P.C. (2009)
|
External Searches for SPG20 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SPG20 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SPG20 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SPG20 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SPG20 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SPG20 |
|
| | |
About This Section
| Patent Information for SPG20 gene:
Search GeneIP for patents involving SPG20
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SPG20 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPG20 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPG20 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPG20 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPG20 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPG20 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPG20 |
| |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPG20 |
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