Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SPESP1 Gene

protein-coding   GIFtS: 38
GCID: GC15P069112

Sperm Equatorial Segment Protein 1

  Search for SPESP1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Sperm Equatorial Segment Protein 11 2
Equatorial Segment Protein2 3
Glycosylated 38 KDa Sperm Protein C-7/82 3
ESP2 3
SP-ESP2 3

External Ids:    HGNC: 155701   Entrez Gene: 2467772   Ensembl: ENSG000002584847   OMIM: 6093995   UniProtKB: Q6UW493   
ORGUL members:         

Export aliases for SPESP1 gene to outside databases

Previous GC identifers: GC00U990975 GC15P066802 GC15P066938 GC15P067010 GC15P067011 GC15P069224 GC15P046056


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SPESP1 Gene:
The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. (provided by RefSeq, Apr
2010)

GeneCards Summary for SPESP1 Gene:
SPESP1 (sperm equatorial segment protein 1) is a protein-coding gene.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the SPESP1 gene promoter:
         RFX1   MIF-1   HNF-4alpha2   Evi-1   HNF-4alpha1   POU2F1   POU2F1b   POU2F1a   HOXA5   POU2F1c   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SPESP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPESP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q23   Ensembl cytogenetic band:  15q23   HGNC cytogenetic band: 15q22.31

SPESP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPESP1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P069112:  view genomic region     (about GC identifiers)

Start:
69,110,560 bp from pter      End:
69,239,150 bp from pter
Size:
128,591 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SPESP_HUMAN, Q6UW49 (See protein sequence)
Recommended Name: Sperm equatorial segment protein 1 precursor  
Size: 350 amino acids; 38931 Da
Secondary accessions: Q8NG22 Q8WVH8

Explore the universe of human proteins at neXtProt for SPESP1: NX_Q6UW49

Explore proteomics data for SPESP1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn128
  • Modification sites at PhosphoSitePlus

  • See SPESP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_663633.1  
    ENSEMBL proteins: 
     ENSP00000312284  

    SPESP1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SPESP1
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SPESP1
    GenScript Custom Purified and Recombinant Proteins Services for SPESP1
    Novus Biologicals SPESP1 Protein
    Novus Biologicals SPESP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SPESP1

     
    Search eBioscience for Proteins for SPESP1 

    SPESP1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SPESP1
    Novus Biologicals SPESP1 Antibodies
    Abcam antibodies for SPESP1
    Cloud-Clone Corp. Antibodies for SPESP1
    Search ThermoFisher Antibodies for SPESP1
    LSBio Antibodies in human, mouse, rat for SPESP1

    SPESP1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SPESP1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SPESP1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SPESP1
    Cloud-Clone Corp. CLIAs for SPESP1
    Search eBioscience for ELISAs for SPESP1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR026743 Equatorial_segment

    Graphical View of Domain Structure for InterPro Entry Q6UW49

    ProtoNet protein and cluster: Q6UW49

    UniProtKB/Swiss-Prot: SPESP_HUMAN, Q6UW49
    Similarity: Belongs to the SPESP1 family


    Find genes that share domains with SPESP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 GenomeRNAi human phenotype for SPESP1:
     Increased homologous recombina 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Spesp1):
     reproductive system 

    Find genes that share phenotypes with SPESP1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Spesp1tm1Osb for SPESP1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPESP1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SPESP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SPESP1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SPESP1

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SPESP1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate SPESP1:
    hsa-miR-656 hsa-miR-4282
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SPESP1
    Predesigned siRNA for gene silencing in human, mouse, rat SPESP1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SPESP1

    Clone
    Products:
         
    OriGene clones in human, mouse for SPESP1 (see all 6)
    OriGene ORF clones in mouse, rat for SPESP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SPESP1 (NM_145658)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPESP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPESP1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SPESP1
    Browse ESI BIO Cell Lines and PureStem Progenitors for SPESP1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPESP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SPESP_HUMAN, Q6UW49: Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Small proacrosomal granules (during
    the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase),
    equatorial segment of the acrosome (during the maturation phase)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    endoplasmic reticulum1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001669acrosomal vesicle IEA--

    Find genes that share ontologies with SPESP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SPESP1
    Interactions:

        Search GeneGlobe Interaction Network for SPESP1

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0007340acrosome reaction IEA--
    GO:0007342fusion of sperm to egg plasma membrane IEA--

    Find genes that share ontologies with SPESP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SPESP1 (SPESP)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SPESP1 gene: 
    NM_145658.3  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000560188 ENST00000310673(uc002arn.2) ENST00000561467
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SPESP1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate SPESP1:
    hsa-miR-656 hsa-miR-4282
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SPESP1
    Predesigned siRNA for gene silencing in human, mouse, rat SPESP1
    Clone
    Products:
         
    OriGene clones in human, mouse for SPESP1 (see all 6)
    OriGene ORF clones in mouse, rat for SPESP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SPESP1 (NM_145658)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPESP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPESP1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SPESP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SPESP1
      QuantiTect SYBR Green Assays in human, mouse, rat SPESP1
      QuantiFast Probe-based Assays in human, mouse, rat SPESP1

    Selected AceView cDNA sequences (see all 94):

    AI797949 BM929516 BE045942 CD107927 AF325190 AF325189 AF353089 NM_024505 
    BQ013471 NM_145658 BF434176 AI652853 BQ215955 BM564110 AY166601 BI826643 
    H52859 CR610432 BU625703 AW340601 AF353088 AI990773 BC017998 AY358983 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SPESP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SPESP1 Expression
    About this image


    SPESP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Testis (Reproductive System)
    SPESP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SPESP1 Protein Expression

    UniProtKB/Swiss-Prot: SPESP_HUMAN, Q6UW49
    Tissue specificity: Highly expressed in testis, where it is localized in the acrosome of postmeiotic stages of
    spermiogenesis (round and elongating spermatids and in ejaculated spermatozoa) (at protein level). Poorly
    expressed in placenta and fetal lung

        Custom PCR Arrays for SPESP1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SPESP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SPESP1
    QuantiTect SYBR Green Assays in human, mouse, rat SPESP1
    QuantiFast Probe-based Assays in human, mouse, rat SPESP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPESP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of human and mouse.

    Orthologs for SPESP1 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spesp11 , 5 sperm equatorial segment protein 11, 5 59.21(n)1
    47.83(a)1
      9 (33.65 cM)5
    667121  NM_025721.21  NP_079997.11 
     622707295 


    ENSEMBL Gene Tree for SPESP1 (if available)
    TreeFam Gene Tree for SPESP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    3 SNPs for SPESP1    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs37430911,2,4
    ----see VAR_0314302 mis40--------
    rs169526841,2,4
    ----see VAR_0569942 mis40--------
    rs37430931,2,4
    ----see VAR_0237382 mis40--------

    HapMap Linkage Disequilibrium report for SPESP1 (69110560 - 69239150 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SPESP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1584CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing SPESP1
    DNA2.0 Custom Variant and Variant Library Synthesis for SPESP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 609399    OMIM disorders: --


    Find genes that share disorders with SPESP1           About GenesLikeMe


    Export disorders for SPESP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SPESP1 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with SPESP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Equatorial segment protein defines a discrete acrosomal subcompartment persisting throughout acrosomal biogenesis. (PubMed id 12773409)1, 2, 3, 9 Wolkowicz M.J.... Herr J.C. (Biol. Reprod. 2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. Equatorial segment protein (ESP) is a human alloantigen involved in sperm-egg binding and fusion. (PubMed id 17978344)1, 9 Wolkowicz M.J....Herr J.C. (J. Androl. 2008)
    5. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (Nat. Biotechnol. 2013)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    7. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (Nature 2006)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Immunogenicity of a multi-component recombinant human acrosomal protein vaccine in female Macaca fascicularis. (PubMed id 17643494)9 Kurth B.E....Herr J.C. (J. Reprod. Immunol. 2008)
    10. Genogrouping and incidence of virulence factors of Enterococcus faecalis in liver transplant patients differ from blood culture and fecal isolates. (PubMed id 11930322)9 Waar K....Degener J.E. (J. Infect. Dis. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 246777 HGNC: 15570 AceView: NOX5 Ensembl:ENSG00000258484 euGenes: HUgn246777
    ECgene: SPESP1 H-InvDB: SPESP1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SPESP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SPESP1 gene:
    Search GeneIP for patents involving SPESP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SPESP1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for SPESP1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SPESP1  
     OriGene qSTAR qPCR primer pairs in human, mouse for SPESP1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SPESP1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SPESP1   OriGene Custom Protein Services for SPESP1  

     
     
     Block miRNA regulation of human, mouse, rat SPESP1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SPESP1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPESP1 Predesigned siRNA for gene silencing in human, mouse, rat SPESP1
     QuantiFast Probe-based Assays in human, mouse, rat SPESP1 QuantiTect SYBR Green Assays in human, mouse, rat SPESP1
     Custom PCR Arrays for SPESP1 Search Chromatin IP Primers for SPESP1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SPESP1  Search GeneGlobe Interaction Network for SPESP1
     Regulatory tfbs in SPESP1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SPESP1 GenScript cDNA clones with any tag delivered in your preferred vector for SPESP1
     GenScript Custom Assay Services for SPESP1 GenScript Custom overexpressing Cell Line Services for SPESP1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SPESP1 (SPESP)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SPESP1 antibodies
     SPESP1 proteins
     SPESP1 lysates
     Antibodies for SPESP1
     See all of Abcam's Antibodies, Kits and Proteins for SPESP1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SPESP1
     Antibodies for SPESP1
     ELISAs for SPESP1
     CLIAs for SPESP1



     Browse ESI BIO Cell Lines and PureStem Progenitors for SPESP1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPESP1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for SPESP1
     Browse SwitchGear Promoter luciferase reporter plasmids for SPESP1
     Search ThermoFisher Antibodies for SPESP1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPESP1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPESP1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SPESP1
     LSBio Antibodies in human, mouse, rat for SPESP1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for SPESP1
      Search eBioscience for proteins for SPESP1
      Search eBioscience for elisas for SPESP1
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SPESP1 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4