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Aliases for SPERT Gene

Aliases for SPERT Gene

  • Spermatid Associated 2 3
  • Spermatid Flower-Like Structure Protein 2 3
  • Protein Chibby Homolog 2 3 4
  • CBY2 3 4
  • Testis Specific Leucine Zipper Protein Nurit 2
  • Testis-Specific Leucine Zipper Protein Nurit 3
  • Novel Leucine Zipper Testicular Protein 3
  • Chibby Homolog 2 (Drosophila) 2
  • Spermatid-Associated Protein 3
  • NURIT 3

External Ids for SPERT Gene

Summaries for SPERT Gene

GeneCards Summary for SPERT Gene

SPERT (Spermatid Associated) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPERT Gene

Genomics for SPERT Gene

Genomic Location for SPERT Gene

Start:
45,702,304 bp from pter
End:
45,714,559 bp from pter
Size:
12,256 bases
Orientation:
Plus strand

Genomic View for SPERT Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPERT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPERT Gene

Regulatory Elements for SPERT Gene

Proteins for SPERT Gene

  • Protein details for SPERT Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NA61-SPERT_HUMAN
    Recommended name:
    Spermatid-associated protein
    Protein Accession:
    Q8NA61
    Secondary Accessions:
    • A8K8I5
    • Q8NHV2

    Protein attributes for SPERT Gene

    Size:
    448 amino acids
    Molecular mass:
    51570 Da
    Quaternary structure:
    • Homodimer. Binds to NEK1 (By similarity).

    Alternative splice isoforms for SPERT Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SPERT Gene

Proteomics data for SPERT Gene at MOPED

Post-translational modifications for SPERT Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPERT Gene

No data available for DME Specific Peptides for SPERT Gene

Domains for SPERT Gene

Protein Domains for SPERT Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SPERT Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NA61

UniProtKB/Swiss-Prot:

SPERT_HUMAN
Family:
  • Belongs to the chibby family. SPERT subfamily.:
    • Q8NA61
genes like me logo Genes that share domains with SPERT: view

No data available for Gene Families for SPERT Gene

Function for SPERT Gene

Gene Ontology (GO) - Molecular Function for SPERT Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with SPERT: view

miRNA for SPERT Gene

miRTarBase miRNAs that target SPERT

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SPERT Gene

Localization for SPERT Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SPERT Gene COMPARTMENTS Subcellular localization image for SPERT gene
Compartment Confidence
nucleus 3
cytosol 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for SPERT Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016023 cytoplasmic membrane-bounded vesicle ISS 12204287
genes like me logo Genes that share ontologies with SPERT: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SPERT Gene

Pathways for SPERT Gene

SuperPathways for SPERT Gene

No Data Available

Gene Ontology (GO) - Biological Process for SPERT Gene

None

No data available for Pathways by source for SPERT Gene

Compounds for SPERT Gene

(1) Novoseek inferred chemical compound relationships for SPERT Gene

Compound -log(P) Hits PubMed IDs
leucine 69.1 6
genes like me logo Genes that share compounds with SPERT: view

Transcripts for SPERT Gene

mRNA/cDNA for SPERT Gene

(4) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPERT Gene

Spermatid associated:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPERT Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c
SP1: -
SP2: - -
SP3:

Relevant External Links for SPERT Gene

GeneLoc Exon Structure for
SPERT
ECgene alternative splicing isoforms for
SPERT

Expression for SPERT Gene

mRNA expression in normal human tissues for SPERT Gene

mRNA differential expression in normal tissues according to GTEx for SPERT Gene

This gene is overexpressed in Testis (52.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SPERT Gene

SOURCE GeneReport for Unigene cluster for SPERT Gene Hs.186363

genes like me logo Genes that share expressions with SPERT: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SPERT Gene

Orthologs for SPERT Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPERT Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SPERT 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SPERT 35
  • 86.94 (n)
  • 81.93 (a)
SPERT 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SPERT 35
  • 83.82 (n)
  • 82.55 (a)
SPERT 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Spert 35
  • 81.95 (n)
  • 79.55 (a)
Spert 16
Spert 36
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SPERT 36
  • 56 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Spert 35
  • 82.21 (n)
  • 79.37 (a)
chicken
(Gallus gallus)
Aves SPERT 35
  • 50.29 (n)
  • 36.59 (a)
SPERT 36
  • 30 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SPERT 36
  • 36 (a)
OneToOne
Species with no ortholog for SPERT:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPERT Gene

ENSEMBL:
Gene Tree for SPERT (if available)
TreeFam:
Gene Tree for SPERT (if available)

Paralogs for SPERT Gene

No data available for Paralogs for SPERT Gene

Variants for SPERT Gene

Sequence variations from dbSNP and Humsavar for SPERT Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs1886792 -- 45,709,723(-) CAGCT(C/T)CACCA intron-variant
rs2031530 -- 45,706,619(+) ACCAG(A/G)AAAGA intron-variant
rs4941529 -- 45,710,563(+) CACAA(C/G)AAAAC intron-variant
rs6561247 -- 45,707,017(+) GCTTG(C/G)CTACC intron-variant
rs6561248 -- 45,707,670(+) GAGGA(C/G)AGGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPERT Gene

Variant ID Type Subtype PubMed ID
dgv250e201 CNV Deletion 23290073

Relevant External Links for SPERT Gene

HapMap Linkage Disequilibrium report
SPERT
Human Gene Mutation Database (HGMD)
SPERT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPERT Gene

Disorders for SPERT Gene

Relevant External Links for SPERT

Genetic Association Database (GAD)
SPERT
genes like me logo Genes that share disorders with SPERT: view

No data available for UniProtKB/Swiss-Prot for SPERT Gene

Publications for SPERT Gene

  1. Nurit, a novel leucine-zipper protein, expressed uniquely in the spermatid flower-like structure. (PMID: 12204287) Feige E. … Motro B. (Mech. Dev. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. A genome-wide scan for signatures of recent selection in Holstein cattle. (PMID: 20096028) Qanbari S. … Simianer H. (Anim. Genet. 2010) 2 3
  4. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for SPERT Gene

Sources for SPERT Gene

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