SPERT Gene
protein-coding GIFtS: 44
GCID: GC13P046276
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spermatid associated
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Aliases
for SPERT gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Spermatid Associated1 2 | | Novel Leucine Zipper Testicular Protein2 | | CBY21 2 3 | | Spermatid Flower-Like Structure Protein2 | | NURIT1 2 | | Spermatid-Associated Protein2 | | Protein Chibby Homolog 22 3 | | Testis Specific Leucine Zipper Protein Nurit2 | | Chibby Homolog 22 | | Testis-Specific Leucine Zipper Protein Nurit2 |
Export aliases for SPERT gene to outside databasesPrevious GC identifers: GC13P045175 GC13P027073 |
Summaries
for SPERT gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SPERT gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SPERT gene promoter:
Max1 Pax-5 AML1a Tal-1beta RORalpha2 E47 AREB6 Sox9 En-1 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for SPERT
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPERT |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q14.13 Ensembl cytogenetic band: 13q14.13 HGNC cytogenetic band: 13q14.13SPERT Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P046276: view genomic region
(about GC identifiers)
Start:
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46,276,446 bp from pter |
End:
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46,288,694 bp from pter |
Size:
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12,249 bases |
Orientation:
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plus strand |
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Proteins
for SPERT gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SPERT_HUMAN, Q8NA61 (See
protein sequence)Recommended Name: Spermatid-associated protein Size: 448 amino acids; 51570 Da
Subunit: Homodimer. Binds to NEK1 (By similarity)
Secondary accessions: A8K8I5 Q8NHV2Alternative splicing: 2 isoforms: Q8NA61-1 Q8NA61-2 Explore the universe of human proteins at neXtProt for SPERT: NX_Q8NA61
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NA61
SPERT Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689932.1
ENSEMBL proteins: ENSP00000309189 ENSP00000435230 ENSP00000368249
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
ISS | 12204287 |
SPERT for ontologies About GeneDecksing
SPERT Antibody Products:
Assay Products for SPERT: |
Protein
Domains /
Families
for SPERT gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SPERT for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8NA61ProtoNet protein and cluster: Q8NA61 UniProtKB/Swiss-Prot: SPERT_HUMAN, Q8NA61Similarity: Belongs to the chibby family. SPERT subfamily |
Function
for SPERT gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPERT (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPERT
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SPERT (NM_152719) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPERT | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPERT |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPERT |
|
Pathways & Interactions
for SPERT gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SPERT
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5 Interacting proteins for SPERT (Q8NA613 ENSP000003091894) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for SPERT gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SPERT for compounds About GeneDecksing
 Browse Tocris compounds for SPERT
1 Novoseek chemical compound relationship for SPERT gene About this table
Search CenterWatch for drugs/clinical trials and news about SPERT
|
Transcripts
for SPERT gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SPERT gene: NM_152719.1 Unigene Cluster for SPERT: Spermatid associated Hs.186363 [show with all ESTs]Unigene Representative Sequence: AK2923503 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000310521(uc001van.1) ENST00000533564 ENST00000378966(uc001vao.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPERT (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPERT
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SPERT (NM_152719) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPERT | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPERT |
Additional cDNA sequence: AK093129.1 AK292350.1 BC027609.2 2 DOTS entries: DT.99999245 DT.75187731 10 AceView cDNA sequences: BC027609 AX747942 NM_152719 AI611034 AK093129 BI462342 BI825284 BG723733 CD359993 BI465179
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for SPERT About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c |
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| SP1: | | | | | | | - | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SPERT
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Expression
for SPERT gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SPERT expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCGGCCAGGA
About this image
See SPERT Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SPERT
SOURCE GeneReport for Unigene cluster: Hs.186363
SABiosciences Custom PCR Arrays for SPERT
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPERT
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SPERT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPERT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPERT | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPERT |
Orthologs
for SPERT gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SPERT gene from 3/8 species (see all 8) About this table
ENSEMBL Gene Tree for SPERT (if available)
TreeFam Gene Tree for SPERT (if available) |
Paralogs
for SPERT gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SPERT gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SPERT (46276446 - 46288694 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SPERT: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPERT |
|
Disorders
/ Diseases
for SPERT gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SPERT for disorders About GeneDecksing
1  disease for SPERT: About MalaCardsretinoblastoma
Export disorders for SPERT gene to outside databases
|
Publications
for SPERT gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SPERT gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with SPERT) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A genome-wide scan for signatures of recent selection in Holstein cattle. (PubMed id 20096028)1, 3 Qanbari S....Simianer H. (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Nurit, a novel leucine-zipper protein, expressed uniquely in the spermatid flower-like structure. (PubMed id 12204287)1, 3 Feige E....Motro B. (2002)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- ASI1, a gene encoding a novel leucine zipper protein, is induced during development of the macronucleus in Tetrahymena. (PubMed id 12351190)9 Udani R.A. and Karrer K.M. (2002)
- RBP95, a novel leucine zipper protein, binds to the retinoblastoma protein. (PubMed id 10944455)9 Wen H. and Ao S. (2000)
- KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity. (PubMed id 9214634)9 Myung K.... Hendrickson E.A. (1997)
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External Searches for SPERT gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing SPERT gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SPERT gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SPERT gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SPERT | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for SPERT gene:
Search GeneIP for patents involving SPERT
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SPERT gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SPERT | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SPERT | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPERT | | | OriGene Protein Over-expression Lysate for SPERT | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SPERT | | OriGene 3'-UTR Clone for SPERT | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPERT | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPERT | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SPERT | | OriGene Custom Protein Services for SPERT | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPERT | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPERT | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPERT | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPERT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPERT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPERT |
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 |  |  |  | |
| | | | Search Tocris compounds for SPERT |
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 | | | SPERT Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPERT |
|  |  |  | | | | ThermoFisher Antibodies for SPERT |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPERT |
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