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Aliases for SPDYE3 Gene

Aliases for SPDYE3 Gene

  • Speedy/RINGO Cell Cycle Regulator Family Member E3 2 3
  • Speedy Homolog E3 (Xenopus Laevis) 2

External Ids for SPDYE3 Gene

Summaries for SPDYE3 Gene

GeneCards Summary for SPDYE3 Gene

SPDYE3 (Speedy/RINGO Cell Cycle Regulator Family Member E3) is a Protein Coding gene. An important paralog of this gene is SPDYA.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPDYE3 Gene

Genomics for SPDYE3 Gene

Genomic Location for SPDYE3 Gene

Start:
100,306,822 bp from pter
End:
100,322,196 bp from pter
Size:
15,375 bases
Orientation:
Plus strand

Genomic View for SPDYE3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPDYE3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPDYE3 Gene

Regulatory Elements for SPDYE3 Gene

Proteins for SPDYE3 Gene

  • Protein details for SPDYE3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NKU9-SPDE3_HUMAN
    Recommended name:
    Speedy protein E3
    Protein Accession:
    A6NKU9
    Secondary Accessions:
    • Q495Y9
    • Q6PHC4

    Protein attributes for SPDYE3 Gene

    Size:
    549 amino acids
    Molecular mass:
    63895 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPDYE3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SPDYE3 Gene

Proteomics data for SPDYE3 Gene at MOPED

Post-translational modifications for SPDYE3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPDYE3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPDYE3 Gene

Domains for SPDYE3 Gene

Gene Families for SPDYE3 Gene

HGNC:
  • SPDY :Speedy homologs

Protein Domains for SPDYE3 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

SPDE3_HUMAN
Family:
  • Belongs to the Speedy/Ringo family.:
    • A6NKU9
genes like me logo Genes that share domains with SPDYE3: view

Function for SPDYE3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SPDYE3 Gene

Localization for SPDYE3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SPDYE3 Gene COMPARTMENTS Subcellular localization image for SPDYE3 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 1

No data available for Gene Ontology (GO) - Cellular Components for SPDYE3 Gene

Pathways for SPDYE3 Gene

SuperPathways for SPDYE3 Gene

No Data Available

Interacting Proteins for SPDYE3 Gene

Gene Ontology (GO) - Biological Process for SPDYE3 Gene

None

No data available for Pathways by source for SPDYE3 Gene

Transcripts for SPDYE3 Gene

mRNA/cDNA for SPDYE3 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPDYE3 Gene

Speedy homolog E3 (Xenopus laevis):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPDYE3 Gene

No ASD Table

Relevant External Links for SPDYE3 Gene

GeneLoc Exon Structure for
SPDYE3
ECgene alternative splicing isoforms for
SPDYE3

Expression for SPDYE3 Gene

mRNA expression in normal human tissues for SPDYE3 Gene

SOURCE GeneReport for Unigene cluster for SPDYE3 Gene Hs.703626

genes like me logo Genes that share expressions with SPDYE3: view

Orthologs for SPDYE3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPDYE3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 81 (a)
OneToMany
-- 37
  • 81 (a)
OneToMany
-- 37
  • 81 (a)
OneToMany
-- 37
  • 81 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 37
  • 49 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 65 (a)
ManyToMany
-- 37
  • 65 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia 4933411G11Rik 37
  • 50 (a)
ManyToMany
Spdyb 37
  • 47 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 33 (a)
ManyToMany
-- 37
  • 34 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 21 (a)
OneToMany
Species with no ortholog for SPDYE3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPDYE3 Gene

ENSEMBL:
Gene Tree for SPDYE3 (if available)
TreeFam:
Gene Tree for SPDYE3 (if available)

Paralogs for SPDYE3 Gene

Paralogs for SPDYE3 Gene

Selected SIMAP similar genes for SPDYE3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPDYE3: view

Variants for SPDYE3 Gene

Sequence variations from dbSNP and Humsavar for SPDYE3 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs858629 -- 100,310,737(+) AGGAG(A/T)CAACA intron-variant
rs858630 -- 100,310,955(+) gaaaa(A/G)ccaag intron-variant
rs858631 -- 100,311,056(+) gagcc(A/G)agatc intron-variant
rs858632 -- 100,311,134(+) GAAGA(A/G)AAAAA intron-variant
rs858635 -- 100,314,557(+) CCCCC(A/G)CGTAG synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for SPDYE3 Gene

Variant ID Type Subtype PubMed ID
esv2734888 CNV Deletion 23290073
nsv428180 CNV Gain 18775914
nsv888774 CNV Gain 21882294
esv26986 CNV Gain 19812545
esv2734890 CNV Deletion 23290073
nsv436898 CNV Insertion 17901297
nsv8183 CNV Gain+Loss 18304495
esv1305604 CNV Deletion 17803354
nsv831071 CNV Loss 17160897

Relevant External Links for SPDYE3 Gene

HapMap Linkage Disequilibrium report
SPDYE3

Disorders for SPDYE3 Gene

No disorders were found for SPDYE3 Gene.

No data available for UniProtKB/Swiss-Prot for SPDYE3 Gene

Publications for SPDYE3 Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3

Products for SPDYE3 Gene

Sources for SPDYE3 Gene

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