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Aliases for SPDYE3 Gene

Aliases for SPDYE3 Gene

  • Speedy/RINGO Cell Cycle Regulator Family Member E3 2 3 5
  • Speedy Homolog E3 (Xenopus Laevis) 2

External Ids for SPDYE3 Gene

Previous GeneCards Identifiers for SPDYE3 Gene

  • GC07P099744
  • GC07P099905
  • GC07P094540

Summaries for SPDYE3 Gene

GeneCards Summary for SPDYE3 Gene

SPDYE3 (Speedy/RINGO Cell Cycle Regulator Family Member E3) is a Protein Coding gene. Among its related pathways are Oocyte meiosis. An important paralog of this gene is SPDYE2B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPDYE3 Gene

Genomics for SPDYE3 Gene

Regulatory Elements for SPDYE3 Gene

Genomic Location for SPDYE3 Gene

100,306,812 bp from pter
100,322,196 bp from pter
15,385 bases
Plus strand

Genomic View for SPDYE3 Gene

Genes around SPDYE3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPDYE3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPDYE3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPDYE3 Gene

Proteins for SPDYE3 Gene

  • Protein details for SPDYE3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Speedy protein E3
    Protein Accession:
    Secondary Accessions:
    • Q495Y9
    • Q6PHC4

    Protein attributes for SPDYE3 Gene

    549 amino acids
    Molecular mass:
    63895 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPDYE3 Gene


neXtProt entry for SPDYE3 Gene

Proteomics data for SPDYE3 Gene at MOPED

Post-translational modifications for SPDYE3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPDYE3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPDYE3 Gene

Domains & Families for SPDYE3 Gene

Gene Families for SPDYE3 Gene

Protein Domains for SPDYE3 Gene


Suggested Antigen Peptide Sequences for SPDYE3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the Speedy/Ringo family.
  • Belongs to the Speedy/Ringo family.
genes like me logo Genes that share domains with SPDYE3: view

Function for SPDYE3 Gene

Phenotypes for SPDYE3 Gene

genes like me logo Genes that share phenotypes with SPDYE3: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPDYE3 Gene

Localization for SPDYE3 Gene

Subcellular locations from

Jensen Localization Image for SPDYE3 Gene COMPARTMENTS Subcellular localization image for SPDYE3 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SPDYE3 Gene

Pathways & Interactions for SPDYE3 Gene

SuperPathways for SPDYE3 Gene

genes like me logo Genes that share pathways with SPDYE3: view

Pathways by source for SPDYE3 Gene

Interacting Proteins for SPDYE3 Gene

Gene Ontology (GO) - Biological Process for SPDYE3 Gene


No data available for SIGNOR curated interactions for SPDYE3 Gene

Drugs & Compounds for SPDYE3 Gene

No Compound Related Data Available

Transcripts for SPDYE3 Gene

mRNA/cDNA for SPDYE3 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPDYE3 Gene

Speedy homolog E3 (Xenopus laevis):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPDYE3 Gene

No ASD Table

Relevant External Links for SPDYE3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPDYE3 Gene

mRNA expression in normal human tissues for SPDYE3 Gene

SOURCE GeneReport for Unigene cluster for SPDYE3 Gene Hs.703626

genes like me logo Genes that share expression patterns with SPDYE3: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPDYE3 Gene

Orthologs for SPDYE3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPDYE3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 49 (a)
(Canis familiaris)
Mammalia -- 36
  • 65 (a)
-- 36
  • 65 (a)
(Mus musculus)
Mammalia 4933411G11Rik 36
  • 50 (a)
Spdyb 36
  • 47 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 33 (a)
-- 36
  • 34 (a)
(Pan troglodytes)
Mammalia -- 36
  • 81 (a)
-- 36
  • 81 (a)
-- 36
  • 81 (a)
-- 36
  • 81 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 21 (a)
Species with no ortholog for SPDYE3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPDYE3 Gene

Gene Tree for SPDYE3 (if available)
Gene Tree for SPDYE3 (if available)

Paralogs for SPDYE3 Gene

Paralogs for SPDYE3 Gene

(9) SIMAP similar genes for SPDYE3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPDYE3: view

Variants for SPDYE3 Gene

Sequence variations from dbSNP and Humsavar for SPDYE3 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs697497 -- 100,310,282(+) GGAGA(A/G)TGGTT intron-variant
rs697498 -- 100,309,101(+) GTGGC(A/G)GAGAC reference, synonymous-codon
rs697499 -- 100,310,143(+) GGGAA(C/G)GATAT intron-variant
rs858628 -- 100,314,275(+) aaaca(A/G)aaaaa intron-variant
rs858629 -- 100,310,737(+) AGGAG(A/T)CAACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPDYE3 Gene

Variant ID Type Subtype PubMed ID
esv2734888 CNV Deletion 23290073
nsv428180 CNV Gain 18775914
nsv888774 CNV Gain 21882294
esv26986 CNV Gain 19812545
esv2734890 CNV Deletion 23290073
nsv436898 CNV Insertion 17901297
nsv8183 CNV Gain+Loss 18304495
esv1305604 CNV Deletion 17803354
nsv831071 CNV Loss 17160897

Variation tolerance for SPDYE3 Gene

Gene Damage Index Score: 0.27; 6.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SPDYE3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPDYE3 Gene

Disorders for SPDYE3 Gene

Relevant External Links for SPDYE3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPDYE3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPDYE3 Gene

Publications for SPDYE3 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SPDYE3 Gene

Sources for SPDYE3 Gene

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