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Aliases for SPDYE2B Gene

Aliases for SPDYE2B Gene

  • Speedy/RINGO Cell Cycle Regulator Family Member E2B 2 3 5
  • Putative Speedy Protein E2-Like Protein 3
  • Putative WBSCR19-Like Protein 3 3
  • WBSCR19-Like Protein 3 3
  • Speedy Protein E2B 3
  • SPDYE2L 3

External Ids for SPDYE2B Gene

Previous GeneCards Identifiers for SPDYE2B Gene

  • GC07P102291

Summaries for SPDYE2B Gene

GeneCards Summary for SPDYE2B Gene

SPDYE2B (Speedy/RINGO Cell Cycle Regulator Family Member E2B) is a Protein Coding gene. Among its related pathways are Oocyte meiosis. An important paralog of this gene is SPDYE6.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPDYE2B Gene

Genomics for SPDYE2B Gene

Genomic Location for SPDYE2B Gene

102,650,325 bp from pter
102,661,400 bp from pter
11,076 bases
Plus strand

Genomic View for SPDYE2B Gene

Genes around SPDYE2B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPDYE2B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPDYE2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPDYE2B Gene

No data available for Regulatory Elements for SPDYE2B Gene

Proteins for SPDYE2B Gene

  • Protein details for SPDYE2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Speedy protein E2B
    Protein Accession:
    Secondary Accessions:
    • D6RBN0

    Protein attributes for SPDYE2B Gene

    402 amino acids
    Molecular mass:
    48290 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPDYE2B Gene


neXtProt entry for SPDYE2B Gene

Post-translational modifications for SPDYE2B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPDYE2B Gene

No data available for DME Specific Peptides for SPDYE2B Gene

Domains & Families for SPDYE2B Gene

Gene Families for SPDYE2B Gene

Protein Domains for SPDYE2B Gene


Suggested Antigen Peptide Sequences for SPDYE2B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the Speedy/Ringo family.
  • Belongs to the Speedy/Ringo family.
genes like me logo Genes that share domains with SPDYE2B: view

Function for SPDYE2B Gene

Gene Ontology (GO) - Molecular Function for SPDYE2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019901 protein kinase binding IBA --
genes like me logo Genes that share ontologies with SPDYE2B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPDYE2B Gene

Localization for SPDYE2B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SPDYE2B Gene

Pathways & Interactions for SPDYE2B Gene

SuperPathways for SPDYE2B Gene

SuperPathway Contained pathways
1 Oocyte meiosis
genes like me logo Genes that share pathways with SPDYE2B: view

Pathways by source for SPDYE2B Gene

2 KEGG pathways for SPDYE2B Gene

Interacting Proteins for SPDYE2B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000424058 for SPDYE2B Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for SPDYE2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045859 regulation of protein kinase activity IBA --
genes like me logo Genes that share ontologies with SPDYE2B: view

No data available for SIGNOR curated interactions for SPDYE2B Gene

Drugs & Compounds for SPDYE2B Gene

No Compound Related Data Available

Transcripts for SPDYE2B Gene

mRNA/cDNA for SPDYE2B Gene

(3) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPDYE2B Gene

No ASD Table

Relevant External Links for SPDYE2B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPDYE2B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SPDYE2B Gene

mRNA differential expression in normal tissues according to GTEx for SPDYE2B Gene

This gene is overexpressed in Testis (x9.2).

NURSA nuclear receptor signaling pathways regulating expression of SPDYE2B Gene:

genes like me logo Genes that share expression patterns with SPDYE2B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPDYE2B Gene

Orthologs for SPDYE2B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPDYE2B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 35
  • 90 (a)
(Canis familiaris)
Mammalia -- 35
  • 66 (a)
-- 35
  • 66 (a)
(Bos Taurus)
Mammalia -- 35
  • 49 (a)
(Mus musculus)
Mammalia 4933411G11Rik 35
  • 49 (a)
Spdyb 35
  • 48 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 35 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 34 (a)
-- 35
  • 33 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 20 (a)
Species where no ortholog for SPDYE2B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPDYE2B Gene

Gene Tree for SPDYE2B (if available)
Gene Tree for SPDYE2B (if available)

Paralogs for SPDYE2B Gene

Paralogs for SPDYE2B Gene

(9) SIMAP similar genes for SPDYE2B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPDYE2B: view

Variants for SPDYE2B Gene

Sequence variations from dbSNP and Humsavar for SPDYE2B Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1044151489 -- 102,656,362(+) GAGGG(C/T)GCAGC intron-variant
rs1052676193 -- 102,663,557(+) TGAAA(A/G)ACAGG intron-variant, downstream-variant-500B
rs1059798 -- 102,661,090(-) AGGAA(A/G)GTTAT intron-variant, utr-variant-3-prime
rs111320873 -- 102,663,581(+) AATTC(C/T)TTGTG intron-variant, downstream-variant-500B
rs111553311 -- 102,660,858(+) GTGAT(A/G)AAGTC intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SPDYE2B Gene

Variant ID Type Subtype PubMed ID
dgv11541n54 CNV loss 21841781
dgv11542n54 CNV loss 21841781
dgv11543n54 CNV loss 21841781
dgv11544n54 CNV loss 21841781
dgv11545n54 CNV loss 21841781
dgv11548n54 CNV loss 21841781
dgv11550n54 CNV loss 21841781
dgv1944e212 CNV loss 25503493
dgv23n31 CNV gain 19718026
dgv3894e59 CNV duplication 20981092
dgv3899e59 CNV duplication 20981092
dgv3900e59 CNV duplication 20981092
dgv3904e59 CNV duplication 20981092
dgv3906e59 CNV duplication 20981092
dgv6538n100 CNV gain 25217958
dgv6539n100 CNV gain 25217958
dgv6540n100 CNV gain 25217958
dgv6541n100 CNV gain 25217958
esv2734946 CNV deletion 23290073
esv27624 CNV gain+loss 19812545
esv2764015 CNV loss 21179565
esv3327844 CNV duplication 20981092
esv3335589 CNV duplication 20981092
esv3343524 CNV duplication 20981092
esv3377591 CNV duplication 20981092
esv3400561 CNV duplication 20981092
esv3424897 CNV duplication 20981092
esv3891168 CNV gain+loss 25118596
esv3891169 CNV gain+loss 25118596
esv3891171 CNV loss 25118596
esv7079 CNV loss 19470904
nsv1027221 CNV loss 25217958
nsv1034233 CNV loss 25217958
nsv1110493 CNV duplication 24896259
nsv1119231 CNV duplication 24896259
nsv1139905 CNV duplication 24896259
nsv1149718 CNV duplication 26484159
nsv428182 CNV gain 18775914
nsv433392 CNV gain 18776910
nsv436086 CNV insertion 17901297
nsv436552 CNV deletion 17901297
nsv469620 CNV loss 16826518
nsv469682 CNV gain+loss 16826518
nsv471643 CNV gain+loss 15918152
nsv482113 CNV gain 20164927
nsv499135 CNV loss 21111241
nsv499529 CNV loss 21111241
nsv509219 CNV insertion 20534489
nsv5879 CNV deletion 18451855
nsv608005 CNV gain 21841781
nsv608046 CNV loss 21841781
nsv608054 CNV loss 21841781
nsv608055 CNV gain 21841781
nsv8192 CNV gain 18304495
nsv831083 CNV loss 17160897
nsv9 CNV deletion 15895083
nsv967349 CNV duplication 23825009
nsv970562 CNV duplication 23825009
nsv970563 CNV duplication 23825009
nsv970921 CNV duplication 23825009
nsv981562 CNV duplication 23825009
nsv981563 CNV duplication 23825009
nsv981678 CNV duplication 23825009

Relevant External Links for SPDYE2B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SPDYE2B Gene

Disorders for SPDYE2B Gene

Relevant External Links for SPDYE2B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPDYE2B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPDYE2B Gene

Publications for SPDYE2B Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 64

Products for SPDYE2B Gene

Sources for SPDYE2B Gene

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