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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SPC25 Gene

protein-coding   GIFtS: 47
GCID: GC02M169690

SPC25, NDC80 Kinetochore Complex Component

(Previous names: spindle pole body component 25 homolog (S. cerevisiae),...)
(Previous symbol: SPBC25)
  Search for SPC25
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
SPC25, NDC80 Kinetochore Complex Component1 2     2600017H08Rik2
SPBC251 2 3     Kinetochore Protein Spc252
hSpc252 3     SPC25, NDC80 Kinetochore Complex Component, Homolog2
SPC25, NDC80 Kinetochore Complex Component, Homolog (S. Cerevisiae)1     Spindle Pole Body Component 25 Homolog2
Spindle Pole Body Component 25 Homolog (S. Cerevisiae)1     

External Ids:    HGNC: 240311   Entrez Gene: 574052   Ensembl: ENSG000001522537   OMIM: 6093955   UniProtKB: Q9HBM13   

Export aliases for SPC25 gene to outside databases

Previous GC identifers: GC02M169436 GC02M161623


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SPC25 Gene:
This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint
activity. (provided by RefSeq, Jul 2008)

GeneCards Summary for SPC25 Gene: 
SPC25 (SPC25, NDC80 kinetochore complex component) is a protein-coding gene. Among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: SPC25_HUMAN, Q9HBM1
Function: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for
chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization
of stable microtubule binding sites in the outer plate of the kinetochore




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_005403.17  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SPC25 gene promoter:
         NF-YA   NF-YC   CBF-C   NF-YB   CBF-B   CBF-A   CP1C   CP1A   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSPC25 promoter sequence
   Search SABiosciences Chromatin IP Primers for SPC25

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPC25


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.1   Ensembl cytogenetic band:  2q31.1   HGNC cytogenetic band: 2q31.1

SPC25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPC25 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M169690:  view genomic region     (about GC identifiers)

Start:
169,690,642 bp from pter      End:
169,769,881 bp from pter
Size:
79,240 bases      Orientation:
minus strand

1 alternative location:
Chr2-,NW_003315909 57,520-77,061     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SPC25_HUMAN, Q9HBM1 (See protein sequence)
Recommended Name: Kinetochore protein Spc25  
Size: 224 amino acids; 26153 Da
Subunit: Component of the NDC80 complex, which consists of NDC80/HEC1, CDCA1, SPBC24 and SPBC25. The NDC80 complex
is formed by two subcomplexes composed of NDC80/HEC1-CDCA1 and SPBC24-SPBC25. Each subcomplex is formed by
parallel interactions through the coiled-coil domains of individual subunits. Formation of a tetrameric complex
is mediated by interactions between the C-terminal regions of both subunits of the NDC80/HEC1-CDCA1 subcomplex
and the N-terminal regions of both subunits of the SPBC24-SPBC25 complex. The tetrameric NDC80 complex has an
elongated rod-like structure with globular domains at either end
Subcellular location: Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late
prophase to anaphase. Localizes specifically to the outer plate of the kinetochore
2 PDB 3D structures from and Proteopedia for SPC25:
2VE7 (3D)        3IZ0 (3D)    
Secondary accessions: A8K4X8 D3DPC0

Explore the universe of human proteins at neXtProt for SPC25: NX_Q9HBM1

Explore proteomics data for SPC25 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9HBM1

  • SPC25 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SPC25 Protein Expression
    REFSEQ proteins: NP_065726.1  
    ENSEMBL proteins: 
     ENSP00000282074   ENSP00000393322  
    Reactome Protein details: Q9HBM1
    Human Recombinant Protein Products for SPC25: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SPC25 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777condensed chromosome kinetochore IDA14699129
    GO:0005634nucleus IEA--
    GO:0005829cytosol TAS--
    GO:0031262Ndc80 complex IDA14699129

    SPC25 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR013255 Spc25

    Graphical View of Domain Structure for InterPro Entry Q9HBM1

    ProtoNet protein and cluster: Q9HBM1

    UniProtKB/Swiss-Prot: SPC25_HUMAN, Q9HBM1
    Similarity: Belongs to the SPC25 family


    SPC25 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SPC25_HUMAN, Q9HBM1
    Function: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for
    chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization
    of stable microtubule binding sites in the outer plate of the kinetochore

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI14699129
         
    SPC25 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for SPC25:
     Cell cycle / mitosis defect  Cell division defect  Increased G2M DNA content  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SPC25 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SPC25 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    3Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/9        Reactome Pathways for SPC25 (see all 9)
        Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase
    Cell Cycle



    SPC25 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SPC25

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/73 Interacting proteins for SPC25 (Q9HBM11, 3 ENSP000002820744) via UniProtKB, MINT, STRING, and/or I2D (see all 73)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDC80O147771, 3, ENSP000002615974EBI-999909,EBI-715849 I2D: score=5 STRING: ENSP00000261597
    SPC24Q8NBT21, 3, ENSP000003971314EBI-999909,EBI-999900 I2D: score=1 STRING: ENSP00000397131
    MIS12Q9H0813, ENSP000003705574I2D: score=2 STRING: ENSP00000370557
    ZWINTO952293, ENSP000003630554I2D: score=2 STRING: ENSP00000363055
    BUB1O436833, ENSP000003025304I2D: score=2 STRING: ENSP00000302530
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0007052mitotic spindle organization IMP14699129
    GO:0007059chromosome segregation IMP14699129
    GO:0007067mitosis IEA--
    GO:0051301cell division IEA--

    SPC25 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SPC25

    Search CenterWatch for drugs/clinical trials and news about SPC25

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SPC25 gene: 
    NM_020675.3  

    Unigene Cluster for SPC25:

    SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
    Hs.421956  [show with all ESTs]
    Unigene Representative Sequence: BC022255
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000479309 ENST00000282074(uc002uel.3) ENST00000451987 ENST00000472216

    miRNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPC25

    Additional mRNA sequence: 

    AF225416.1 AK291093.1 AY456388.1 BC022255.1 CR457197.1 

    3 DOTS entries:

    DT.113739  DT.75117421  DT.95160225 

    24/84 AceView cDNA sequences (see all 84):

    CK825801 AA761074 CR610550 NM_020675 AA287517 CR457197 BX105588 AA286680 
    AI990567 BI093154 BG236186 AY456388 AA707088 AA701565 CR590224 BQ441900 
    AA521130 AI656904 AA533110 BE264670 AA628540 BU928598 BM455908 AW510998 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SPC25 expression in normal human tissues (normalized intensities)      SPC25 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SPC25 Expression
    About this image


    SPC25 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Adult Oligodendrocyte Precursor Cells Lateral Ventricle
     
     Heart (Cardiovascular System)
             Cardiac Fibroblasts Myocardium
     
     Testis (Reproductive System)
             Pre-Sertoli Cells Testis Cord
     
     Gonad
             XX Germ Cells Ovigerous Cord

    See SPC25 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SPC25

    SOURCE GeneReport for Unigene cluster: Hs.421956
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SPC25 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spc251 , 5 SPC25, NDC80 kinetochore complex component, homolog more1, 5 81.1(n)1
    74.55(a)1
      2 (39.64 cM)5
    664421  NM_001199124.11  NP_001186053.11 
     691938955 
    chicken
    (Gallus gallus)
    Aves SPC251 SPC25, NDC80 kinetochore complex component, homolog more 62.84(n)
    48.62(a)
      424172  XM_422018.2  XP_422018.1 
    lizard
    (Anolis carolinensis)
    Reptilia SPC256
    SPC25, NDC80 kinetochore complex component, homolo...
    29(a)
    1 ↔ 1
    1(245297868-245307284)
    zebrafish
    (Danio rerio)
    Actinopterygii spc251 SPC25, NDC80 kinetochore complex component, homolog more 52.44(n)
    38.01(a)
      100144563  NM_001123057.1  NP_001116529.1 


    ENSEMBL Gene Tree for SPC25 (if available)
    TreeFam Gene Tree for SPC25 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/499 SNPs in SPC25 are shown (see all 499)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1865432111,2
    C--169727075(+) CACTTC/GTCAAA 1 -- ds50010--------
    rs1921511881,2
    --169727395(+) TCATGC/TTGCTA 1 -- ds50010--------
    rs1431489121,2
    C--169727582(+) TGAAGA/CTGGAA 1 -- ut310--------
    rs1113722831,2
    C--169727610(+) ACTATT/CGAAAG 1 -- ut312Minor allele frequency- C:0.33CSA 3
    rs67349231,2
    C,F,A,H--169727730(+) gggagC/Ggggga 1 -- ut31 trp35Minor allele frequency- G:0.44NA CSA 9
    rs621767811,2
    C,F--169727863(+) GTATAG/ATAATA 1 -- ut311Minor allele frequency- A:0.50NA 2
    rs114205141,2
    C--169727877(+) ACAAGA/-AAAAA 1 -- ut31 trp31Minor allele frequency- -:0.00CSA 2
    rs615988341,2
    C--169727880(+) AAAAGA/-AGATA 1 -- ut311Minor allele frequency- -:0.00NA 2
    rs1867845841,2
    C--169727916(+) TAAACC/TGTTTT 1 -- ut310--------
    rs1508485051,2
    C--169727953(+) TAAACC/TGTGGC 2 T syn11Minor allele frequency- T:0.00NA 4536

    HapMap Linkage Disequilibrium report for SPC25 (169690642 - 169769881 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SPC25:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv227CNV Insertion15895083
    esv999271CNV Insertion20482838
    nsv3023CNV Insertion18451855
    nsv875381CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SPC25 for disorders           About MalaCards
    OMIM gene information: 609395    OMIM disorders: --


    SPC25 for disorders           About GeneDecksing


    Export disorders for SPC25 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SPC25 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with SPC25)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore. (PubMed id 15961401)1, 2 Ciferri C.... Musacchio A. (2005)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    3. Identification of two novel components of the human NDC80 kinetochore complex. (PubMed id 14699129)1, 2 Bharadwaj R.... Yu H. (2004)
    4. The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. (PubMed id 14738735)1, 2 McCleland M.L.... Stukenberg P.T. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. (PubMed id 22678362)1 Stehling O....Lill R. (2012)
    9. Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction. (PubMed id 22371557)1 Chan Y.W....Santamaria A. (2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57405 HGNC: 24031 AceView: Spc25 Ensembl:ENSG00000152253 euGenes: HUgn57405
    ECgene: SPC25 H-InvDB: SPC25

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SPC25 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SPC25 gene:
    Search GeneIP for patents involving SPC25

    GeneCards and IP:
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