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Aliases for SPATS2L Gene

Aliases for SPATS2L Gene

  • Spermatogenesis Associated, Serine-Rich 2-Like 2 3
  • SGNP 3 4 6
  • DNA Polymerase Transactivated Protein 6 2 3
  • DNA Polymerase-Transactivated Protein 6 3 4
  • Stress Granule And Nucleolar Protein 3 4
  • DNAPTP6 3 4
  • SPATS2-Like Protein 3

External Ids for SPATS2L Gene

Previous GeneCards Identifiers for SPATS2L Gene

  • GC02P200881
  • GC02P201170
  • GC02P193023

Summaries for SPATS2L Gene

GeneCards Summary for SPATS2L Gene

SPATS2L (Spermatogenesis Associated, Serine-Rich 2-Like) is a Protein Coding gene. An important paralog of this gene is SPATS2.

Gene Wiki entry for SPATS2L Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATS2L Gene

Genomics for SPATS2L Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SPATS2L Gene

200,305,881 bp from pter
200,482,263 bp from pter
176,383 bases
Plus strand

Genomic View for SPATS2L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATS2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATS2L Gene

No data available for Regulatory Elements for SPATS2L Gene

Proteins for SPATS2L Gene

  • Protein details for SPATS2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    SPATS2-like protein
    Protein Accession:
    Secondary Accessions:
    • A8K381
    • B4DRE6
    • B4DT67
    • B7WNZ7
    • Q53T22
    • Q8WV53
    • Q8WYG1
    • Q9NTW4

    Protein attributes for SPATS2L Gene

    558 amino acids
    Molecular mass:
    61729 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAG22487.1; Type=Frameshift; Positions=92; Evidence={ECO:0000305};

    Alternative splice isoforms for SPATS2L Gene


neXtProt entry for SPATS2L Gene

Proteomics data for SPATS2L Gene at MOPED

Post-translational modifications for SPATS2L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for SPATS2L

No data available for DME Specific Peptides for SPATS2L Gene

Domains for SPATS2L Gene

Protein Domains for SPATS2L Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATS2 family.
  • Belongs to the SPATS2 family.
genes like me logo Genes that share domains with SPATS2L: view

No data available for Gene Families for SPATS2L Gene

Function for SPATS2L Gene

Gene Ontology (GO) - Molecular Function for SPATS2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with SPATS2L: view

Phenotypes for SPATS2L Gene

GenomeRNAi human phenotypes for SPATS2L:
genes like me logo Genes that share phenotypes with SPATS2L: view

Animal Model Products

CRISPR Products

miRNA for SPATS2L Gene

miRTarBase miRNAs that target SPATS2L

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATS2L

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for SPATS2L Gene

Localization for SPATS2L Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATS2L Gene

Cytoplasm. Nucleus, nucleolus. Note=During oxidative stress as well as UV irradiation, energy deprivation or heat shock, relocalizes to cytoplasmic stress granules. In the nucleus, found in structures lacking NPM1.

Subcellular locations from

Jensen Localization Image for SPATS2L Gene COMPARTMENTS Subcellular localization image for SPATS2L gene
Compartment Confidence
nucleus 5
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for SPATS2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm IDA --
GO:0043234 protein complex IDA --
genes like me logo Genes that share ontologies with SPATS2L: view

Pathways for SPATS2L Gene

SuperPathways for SPATS2L Gene

No Data Available

Interacting Proteins for SPATS2L Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000351503 Q9NUQ6-SPS2L_HUMAN for SPATS2L Gene via STRING I2D

Gene Ontology (GO) - Biological Process for SPATS2L Gene


No data available for Pathways by source for SPATS2L Gene

Transcripts for SPATS2L Gene

Unigene Clusters for SPATS2L Gene

Spermatogenesis associated, serine-rich 2-like:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATS2L

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATS2L Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b
SP1: -
SP2: - -

Relevant External Links for SPATS2L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATS2L Gene

mRNA expression in normal human tissues for SPATS2L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for SPATS2L Gene

This gene is overexpressed in Lung (62.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SPATS2L Gene

SOURCE GeneReport for Unigene cluster for SPATS2L Gene Hs.120323

genes like me logo Genes that share expressions with SPATS2L: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for SPATS2L Gene

Orthologs for SPATS2L Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPATS2L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPATS2L 35
  • 90.72 (n)
  • 93.09 (a)
  • 93 (a)
(Canis familiaris)
Mammalia SPATS2L 35
  • 91.76 (n)
  • 93.82 (a)
  • 94 (a)
(Mus musculus)
Mammalia Spats2l 35
  • 87.96 (n)
  • 89.03 (a)
Spats2l 16
Spats2l 36
  • 86 (a)
(Pan troglodytes)
Mammalia SPATS2L 35
  • 99.88 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Spats2l 35
  • 87.97 (n)
  • 90.48 (a)
(Monodelphis domestica)
Mammalia SPATS2L 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia SPATS2L 36
  • 51 (a)
(Gallus gallus)
Aves SPATS2L 35
  • 72.59 (n)
  • 68.57 (a)
  • 65 (a)
(Anolis carolinensis)
Reptilia SPATS2L 36
  • 60 (a)
Species with no ortholog for SPATS2L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATS2L Gene

Gene Tree for SPATS2L (if available)
Gene Tree for SPATS2L (if available)

Paralogs for SPATS2L Gene

Paralogs for SPATS2L Gene

genes like me logo Genes that share paralogs with SPATS2L: view

Variants for SPATS2L Gene

Sequence variations from dbSNP and Humsavar for SPATS2L Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs159320 -- 200,323,052(-) GAGAT(C/T)TGAAG intron-variant
rs159321 -- 200,319,990(-) TGCAA(C/T)TGATA intron-variant
rs159322 -- 200,318,736(-) TATCA(C/G)TGAGT intron-variant
rs159430 -- 200,370,064(-) AATCC(C/G/T)GGCCA intron-variant
rs192680 -- 200,364,167(+) ATCCT(C/T)CTCTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPATS2L Gene

Variant ID Type Subtype PubMed ID
nsv3107 CNV Loss 18451855
nsv875706 CNV Gain 21882294
esv268686 CNV Insertion 20981092
nsv507061 CNV Insertion 20534489
esv1009509 CNV Insertion 20482838
nsv213509 CNV Insertion 16902084
nsv3108 CNV Loss 18451855
esv2677584 CNV Deletion 23128226
esv269068 CNV Insertion 20981092
esv2658982 CNV Deletion 23128226
nsv819248 CNV Gain 19587683
nsv517769 CNV Gain+Loss 19592680
nsv875707 CNV Gain 21882294

Relevant External Links for SPATS2L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATS2L Gene

Disorders for SPATS2L Gene

Relevant External Links for SPATS2L

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for SPATS2L Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SPATS2L Gene

Publications for SPATS2L Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. SGNP: an essential stress granule/nucleolar protein potentially involved in 5.8s rRNA processing/transport. (PMID: 19005571) Zhu C.H. … Wright W.E. (PLoS ONE 2008) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for SPATS2L Gene

Sources for SPATS2L Gene

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