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SPATS2L Gene

protein-coding   GIFtS: 50
GCID: GC02P201170

Spermatogenesis Associated, Serine-Rich 2-Like

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Spermatogenesis Associated, Serine-Rich 2-Like1 2     DNAPTP62 3
SGNP2 3 5     DNA Polymerase-Transactivated Protein 62 3
DNA Polymerase Transactivated Protein 61 2     SPATS2-Like Protein2
Stress Granule And Nucleolar Protein2 3     

External Ids:    HGNC: 245741   Entrez Gene: 260102   Ensembl: ENSG000001961417   OMIM: 6138175   UniProtKB: Q9NUQ63   

Export aliases for SPATS2L gene to outside databases

Previous GC identifers: GC02P200881 GC02P193023


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SPATS2L Gene:
SPATS2L (spermatogenesis associated, serine-rich 2-like) is a protein-coding gene. An important paralog of this gene is SPATS2.

Gene Wiki entry for SPATS2L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SPATS2L
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SPATS2L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPATS2L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33.1   Ensembl cytogenetic band:  2q33.1   HGNC cytogenetic band: 2q33.1

SPATS2L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPATS2L gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P201170:  view genomic region     (about GC identifiers)

Start:
201,170,604 bp from pter      End:
201,346,986 bp from pter
Size:
176,383 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SPS2L_HUMAN, Q9NUQ6 (See protein sequence)
Recommended Name: SPATS2-like protein  
Size: 558 amino acids; 61729 Da
Sequence caution: Sequence=AAG22487.1; Type=Frameshift; Positions=92;
Secondary accessions: A8K381 B7WNZ7 Q53T22 Q8WV53 Q8WYG1 Q9NTW4
Alternative splicing: 2 isoforms:  Q9NUQ6-1   Q9NUQ6-2   

Explore the universe of human proteins at neXtProt for SPATS2L: NX_Q9NUQ6

Explore proteomics data for SPATS2L at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SPATS2L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001093892.1  NP_001093893.1  NP_001093894.1  NP_001269664.1  NP_001269672.1  NP_001269673.1  NP_056350.2  

    ENSEMBL proteins: 
     ENSP00000406728   ENSP00000386336   ENSP00000351503   ENSP00000386931   ENSP00000386391  
     ENSP00000411294   ENSP00000405506   ENSP00000391467   ENSP00000353989   ENSP00000396109  
     ENSP00000398198   ENSP00000389908   ENSP00000390506   ENSP00000386730   ENSP00000386600  
     ENSP00000386310   ENSP00000402559   ENSP00000413142   ENSP00000413648   ENSP00000405751  
     ENSP00000387333  

    SPATS2L Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SPATS2L

     
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    Search eBioscience for ELISAs for SPATS2L 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR009816 DUF1387
     IPR009060 UBA-like

    Graphical View of Domain Structure for InterPro Entry Q9NUQ6

    ProtoNet protein and cluster: Q9NUQ6

    UniProtKB/Swiss-Prot: SPS2L_HUMAN, Q9NUQ6
    Similarity: Belongs to the SPATS2 family


    Find genes that share domains with SPATS2L           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with SPATS2L           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SPATS2L:
     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPATS2L
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SPATS2L
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SPATS2L

    miRNA
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    miRTarBase miRNAs that target SPATS2L:
    hsa-mir-146a-5p (MIRT021247), hsa-mir-21-5p (MIRT004812), hsa-mir-103a-3p (MIRT027221)

    Block miRNA regulation of human, mouse, rat SPATS2L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SPATS2L (see all 99):
    hsa-miR-579 hsa-miR-607 hsa-miR-134 hsa-miR-632 hsa-miR-4325 hsa-miR-3613-3p hsa-miR-489 hsa-miR-3116
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SPATS2L

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATS2L

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATS2L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SPS2L_HUMAN, Q9NUQ6: Cytoplasm. Nucleus, nucleolus. Note=During oxidative stress as well as UV irradiation,
    energy deprivation or heat shock, relocalizes to cytoplasmic stress granules. In the nucleus, found in structures
    lacking NPM1
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    cytoskeleton1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0043234protein complex ----

    Find genes that share ontologies with SPATS2L           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SPATS2L
    Interactions:

        Search GeneGlobe Interaction Network for SPATS2L

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SPATS2L (Q9NUQ63 ENSP000003515034) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SUMO1P631653, ENSP000003760764I2D: score=1 STRING: ENSP00000376076
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SPATS2L (SPS2L)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SPATS2L gene (7 alternative transcripts): 
    NM_001100422.1  NM_001100423.1  NM_001100424.1  NM_001282735.1  NM_001282743.1  NM_001282744.1  NM_015535.2  

    Unigene Cluster for SPATS2L:

    Spermatogenesis associated, serine-rich 2-like
    Hs.120323  [show with all ESTs]
    Unigene Representative Sequence: NM_001100422
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27):
    ENST00000439084 ENST00000409718(uc002uvn.4 uc010fst.3 uc002uvo.4)
    ENST00000358677(uc010zhc.2) ENST00000409988(uc002uvp.4 uc002uvq.4)
    ENST00000409385 ENST00000439395 ENST00000444012 ENST00000451764 ENST00000360760
    ENST00000423749 ENST00000428692 ENST00000471601 ENST00000457757 ENST00000453663
    ENST00000409140(uc002uvr.4) ENST00000459656 ENST00000471533 ENST00000409397

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SPATS2L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SPATS2L (see all 99):
    hsa-miR-579 hsa-miR-607 hsa-miR-134 hsa-miR-632 hsa-miR-4325 hsa-miR-3613-3p hsa-miR-489 hsa-miR-3116
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SPATS2L
    Clone
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    OriGene clones in human, mouse for SPATS2L (see all 24)
    OriGene ORF clones in mouse, rat for SPATS2L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): SPATS2L (NM_015535)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPATS2L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATS2L
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SPATS2L
      QuantiTect SYBR Green Assays in human, mouse, rat SPATS2L
      QuantiFast Probe-based Assays in human, mouse, rat SPATS2L

    Additional mRNA sequence: 

    AF193059.1 AK002064.1 AK021816.1 AK024200.1 AK090703.1 AK090867.1 AK092917.1 AK290496.1 
    AK299223.1 AK300075.1 AK314561.1 AL110124.1 AY450394.1 BC010848.1 BC018736.1 BC065817.1 
    BX537813.1 

    Selected DOTS entries (see all 37):

    DT.100646990  DT.100866267  DT.100646986  DT.449468  DT.97859725  DT.120995079  DT.100646983  DT.75169050 
    DT.100741545  DT.95232593  DT.101968325  DT.100030252  DT.91969720  DT.120995127  DT.91752373  DT.99930021 
    DT.97794041  DT.101985024  DT.40255740  DT.102834666  DT.120995156  DT.91870562  DT.99933106  DT.100030249 

    Selected AceView cDNA sequences (see all 410):

    AI828334 BX953095 AW769165 BP334458 BQ574386 BF026314 BE855442 AI344751 
    BE000407 BM828928 AA827517 AI559820 AI862362 CD370013 BU676055 BF477612 
    BQ019063 BQ009139 BM552561 AA878165 BP365082 AA701247 CR617341 BQ232947 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SPATS2L    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b
    SP1:                                            -                           
    SP2:                    -                       -                           
    SP3:                                                                        


    ECgene alternative splicing isoforms for SPATS2L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SPATS2L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGCTTTTGTA
    SPATS2L Expression
    About this image


    SPATS2L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Endothelium (Cardiovascular System)
             Endothelial-like cells
    SPATS2L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SPATS2L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.120323
        Custom PCR Arrays for SPATS2L
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SPATS2L gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spats2l1 , 5 spermatogenesis associated, serine-rich 2-like1, 5 87.96(n)1
    89.03(a)1
      1 (28.85 cM)5
    671981  NM_144882.41  NP_659131.21 
     577741625 
    chicken
    (Gallus gallus)
    Aves SPATS2L1 spermatogenesis associated, serine-rich 2-like 72.59(n)
    68.57(a)
      424067  NM_001008474.1  NP_001008474.1 
    lizard
    (Anolis carolinensis)
    Reptilia SPATS2L6
    spermatogenesis associated, serine-rich 2-like
    60(a)
    1 ↔ 1
    1(117651476-117726934)


    ENSEMBL Gene Tree for SPATS2L (if available)
    TreeFam Gene Tree for SPATS2L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SPATS2L gene
    SPATS22  
    Selected SIMAP similar genes for SPATS2L using alignment to 16 protein entries:     SPS2L_HUMAN (see all proteins) (see all similar genes):
    AURA2    NFS1    SH3PXD2A    ZNF283    LEPROTL1    RUFY1
    DCK    DCTN5    PHC3    TMEM14B    SPATS2    CTSS
    RBBP4    APOD    BTBD2    ERBB2    PKN1    RBMS2

    Find genes that share paralogs with SPATS2L           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SPATS2L (see all 3017)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1922979051,2
    --201168624(+) CAATAC/TTGTCA 1 -- us2k10--------
    rs1836824631,2
    --201168668(+) TGTAAC/TTTTTC 1 -- us2k10--------
    rs556772331,2
    C,F--201168695(+) TCTGGT/CGAAAA 1 -- us2k17Minor allele frequency- C:0.44NA CSA WA EA 365
    rs2951511,2
    C--201168703(-) TGTTGG/ATGTTT 1 -- us2k111Minor allele frequency- A:0.01NA WA CSA EA 372
    rs1420480381,2
    C--201168728(+) ATTTTG/TTTTCT 1 -- us2k10--------
    rs1870354511,2
    --201168746(+) TTTCTA/GTCTCC 1 -- us2k10--------
    rs563265331,2
    C,F--201168758(+) TATAAT/CAATAG 1 -- us2k16Minor allele frequency- C:0.44NA CSA WA EA 363
    rs1914808931,2
    --201168796(+) TTATGC/TCTAAT 1 -- us2k10--------
    rs621795051,2
    C,F--201168851(+) TTTACA/GTGTTT 1 -- us2k12Minor allele frequency- G:0.13NA 122
    rs1828190481,2
    --201168866(+) AAGCAC/TATTAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SPATS2L (201170604 - 201346986 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SPATS2L (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2677584CNV Deletion23128226
    esv2658982CNV Deletion23128226
    esv269068CNV Insertion20981092
    nsv507061CNV Insertion20534489
    esv268686CNV Insertion20981092
    esv1009509CNV Insertion20482838
    nsv213509CNV Insertion16902084
    nsv3107CNV Loss18451855
    nsv3108CNV Loss18451855
    nsv875706CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SPATS2L
    DNA2.0 Custom Variant and Variant Library Synthesis for SPATS2L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613817    OMIM disorders: --


    Find genes that share disorders with SPATS2L           About GenesLikeMe

    Genetic Association Database (GAD): SPATS2L
    Human Genome Epidemiology (HuGE) Navigator: SPATS2L (4 documents)

    Export disorders for SPATS2L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SPATS2L gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with SPATS2L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. SGNP: an essential stress granule/nucleolar protein potentially involved in 5.8s rRNA processing/transport. (PubMed id 19005571)1, 2 Zhu C.H.... Wright W.E. (PLoS ONE 2008)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PubMed id 23974872)1 Ripke S....Sullivan P.F. (Nat. Genet. 2013)
    6. Fine-mapping of restless legs locus 4 (RLS4) identifies a haplotype over the SPATS2L and KCTD18 genes. (PubMed id 23054586)1 Pichler I....Pramstaller P.P. (J. Mol. Neurosci. 2013)
    7. Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. (PubMed id 22792082)1 Himes B.E....Weiss S.T. (PLoS Genet. 2012)
    8. A bead-based approach for large-scale identification of in vitro kinase substrates. (PubMed id 22113938)1 Zhang M....Zou H. (Proteomics 2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26010 HGNC: 24574 AceView: DNAPTP6 Ensembl:ENSG00000196141 euGenes: HUgn26010
    ECgene: SPATS2L H-InvDB: SPATS2L

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SPATS2L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SPATS2L gene:
    Search GeneIP for patents involving SPATS2L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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