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SPATS2 Gene

protein-coding   GIFtS: 47
GCID: GC12P049760

Spermatogenesis Associated, Serine-Rich 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Spermatogenesis Associated, Serine-Rich 21 2     Putative Protein Product Of Nbla005262
SCR592 3 5     Serine-Rich Spermatocytes And Round Spermatid Protein2
SPATA102 3 5     Spermatogenesis-Associated Serine-Rich Protein 22
Serine-Rich Spermatocytes And Round Spermatid 59 KDa Protein2 3     p59scr3
P59SCR2 5     

External Ids:    HGNC: 186501   Entrez Gene: 652442   Ensembl: ENSG000001233527   OMIM: 6116675   UniProtKB: Q86XZ43   

Export aliases for SPATS2 gene to outside databases

Previous GC identifers: GC12P049477 GC12P048047 GC12P046791


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SPATS2 Gene:
SPATS2 (spermatogenesis associated, serine-rich 2) is a protein-coding gene. An important paralog of this gene is SPATS2L.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SPATS2 gene promoter:
         Bach1   STAT5B   Sp1   AML1a   STAT5A   Tal-1beta   E47   Sox9   MRF-2   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSPATS2 promoter sequence
   Search Chromatin IP Primers for SPATS2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPATS2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.12   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13.12

SPATS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPATS2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P049760:  view genomic region     (about GC identifiers)

Start:
49,760,367 bp from pter      End:
49,921,207 bp from pter
Size:
160,841 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SPAS2_HUMAN, Q86XZ4 (See protein sequence)
Recommended Name: Spermatogenesis-associated serine-rich protein 2  
Size: 545 amino acids; 59545 Da
Sequence caution: Sequence=BAB14448.1; Type=Erroneous initiation; Sequence=BAB14958.1; Type=Erroneous initiation;
Secondary accessions: A8K8G9 Q9H7D4 Q9H8Y7 Q9H8Z8

Explore the universe of human proteins at neXtProt for SPATS2: NX_Q86XZ4

Explore proteomics data for SPATS2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SPATS2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_075559.2  
    ENSEMBL proteins: 
     ENSP00000449406   ENSP00000447296   ENSP00000447131   ENSP00000447526   ENSP00000448459  
     ENSP00000448830   ENSP00000449623   ENSP00000449509   ENSP00000446900   ENSP00000448228  
     ENSP00000326841   ENSP00000448522   ENSP00000447947   ENSP00000449738   ENSP00000449615  
     ENSP00000448174   ENSP00000449431  

    SPATS2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SPATS2

     
    Search eBioscience for Proteins for SPATS2 

     
    antibodies-online proteins for SPATS2 (2 products) 

     
    Search antibodies-online for peptides for SPATS2

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    Search eBioscience for ELISAs for SPATS2 
    antibodies-online kits for SPATS2 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR009816 DUF1387
     IPR009060 UBA-like

    Graphical View of Domain Structure for InterPro Entry Q86XZ4

    ProtoNet protein and cluster: Q86XZ4

    UniProtKB/Swiss-Prot: SPAS2_HUMAN, Q86XZ4
    Similarity: Belongs to the SPATS2 family


    Find genes that share domains with SPATS2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with SPATS2           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for SPATS2

    miRNA
    Products:
        
    miRTarBase miRNAs that target SPATS2:
    hsa-mir-296-3p (MIRT038487), hsa-let-7a-5p (MIRT052478), hsa-mir-103a-3p (MIRT026989), hsa-mir-590-3p (MIRT016175)

    Block miRNA regulation of human, mouse, rat SPATS2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SPATS2 (see all 25):
    hsa-miR-3685 hsa-miR-137 hsa-miR-4272 hsa-miR-509-5p hsa-miR-657 hsa-miR-944 hsa-miR-583 hsa-miR-4314
    SwitchGear 3'UTR luciferase reporter plasmidSPATS2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SPATS2
    Predesigned siRNA for gene silencing in human, mouse, rat SPATS2

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 4): SPATS2 (NM_015535)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPATS2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATS2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for SPATS2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATS2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SPAS2_HUMAN, Q86XZ4: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with SPATS2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SPATS2
    Interactions:

        Search GeneGlobe Interaction Network for SPATS2

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SPATS2 (SPAS2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SPATS2 gene: 
    NM_023071.3  

    Unigene Cluster for SPATS2:

    Spermatogenesis associated, serine-rich 2
    Hs.654826  [show with all ESTs]
    Unigene Representative Sequence: NM_023071
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000550997 ENST00000549538 ENST00000548654 ENST00000550643 ENST00000549412
    ENST00000548710 ENST00000549179 ENST00000548377 ENST00000549298 ENST00000549375
    ENST00000553127(uc001rud.2 uc001rue.2 uc009zli.1 uc001ruf.2)
    ENST00000321898 ENST00000551540 ENST00000552918 ENST00000548777 ENST00000548388
    ENST00000547865(uc001ruc.3) ENST00000552171
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SPATS2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SPATS2 (see all 25):
    hsa-miR-3685 hsa-miR-137 hsa-miR-4272 hsa-miR-509-5p hsa-miR-657 hsa-miR-944 hsa-miR-583 hsa-miR-4314
    SwitchGear 3'UTR luciferase reporter plasmidSPATS2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SPATS2
    Predesigned siRNA for gene silencing in human, mouse, rat SPATS2
    Clone
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    OriGene clones in human, mouse for SPATS2 (see all 7)
    OriGene ORF clones in mouse, rat for SPATS2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): SPATS2 (NM_015535)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPATS2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATS2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SPATS2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SPATS2
      QuantiTect SYBR Green Assays in human, mouse, rat SPATS2
      QuantiFast Probe-based Assays in human, mouse, rat SPATS2

    Additional mRNA sequence: 

    AB075515.1 AK023179.1 AK023202.1 AK024678.1 AK095582.1 AK292334.1 AL833614.1 BC017767.1 
    BC032441.1 BC048299.1 BX648916.1 

    20 DOTS entries:

    DT.95274334  DT.100755504  DT.206064  DT.100755507  DT.95274333  DT.95274335  DT.95356223  DT.100755506 
    DT.91976695  DT.100024792  DT.101972709  DT.121147890  DT.121147893  DT.91755583  DT.95154342  DT.97784261 
    DT.100699200  DT.121147833  DT.40191074  DT.97792405 

    Selected AceView cDNA sequences (see all 159):

    CD674998 BC048299 AA937342 BM503484 BQ707498 AW873588 AV646767 BM503322 
    AA836396 AK095582 AI923329 BM828628 T07547 CA418208 AI791414 AW304709 
    BQ879622 T32690 BE047679 AL558178 BI517324 BM549283 BQ215926 AI359986 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SPATS2 (see all 19)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^
    SP1:                                                                          -     -     -     -                       -     -           -                     
    SP2:                                                                    -     -     -     -     -                       -     -           -                     
    SP3:                                                                                                                    -     -                                 
    SP4:                                                                                                                                                            
    SP5:        -     -     -     -     -     -     -     -     -     -     -     -     -     -     -                       -     -           -                     

    ExUns: 15 ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b · 25c · 25d
    SP1:  -           -                                                                                 
    SP2:  -           -                             -                                                   
    SP3:  -           -                                                                                 
    SP4:              -                                                                                 
    SP5:  -                                                                                             


    ECgene alternative splicing isoforms for SPATS2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SPATS2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGCCCAGCC
    SPATS2 Expression
    About this image


    SPATS2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Cardiovascular System)
             Conventional Dendritic Cells II Spleen
     
     Spleen (Hematopoietic System)
             Conventional Dendritic Cells II Spleen
    SPATS2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SPATS2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654826
        Custom PCR Arrays for SPATS2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATS2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SPATS2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spats21 , 5 spermatogenesis associated, serine-rich 21, 5 83.64(n)1
    83.82(a)1
      15 (56.01 cM)5
    725721  NM_139140.11  NP_631879.11 
     991268455 
    chicken
    (Gallus gallus)
    Aves SPATS21 spermatogenesis associated, serine-rich 2 69.04(n)
    70.13(a)
      426663  XM_424288.4  XP_424288.3 
    lizard
    (Anolis carolinensis)
    Reptilia SPATS26
    spermatogenesis associated, serine-rich 2
    62(a)
    1 ↔ 1
    GL343198.1(2159671-2179178)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC691172 hypothetical protein MGC69117 75.27(n)    BC057748.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hcrtr22 hypocretin (orexin) receptor 2 72.3(n)   378447  AL915203.1 


    ENSEMBL Gene Tree for SPATS2 (if available)
    TreeFam Gene Tree for SPATS2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SPATS2 gene
    SPATS2L2  
    2 SIMAP similar genes for SPATS2 using alignment to 11 protein entries:     SPAS2_HUMAN (see all proteins):
    ZNF268    SPATS2L

    Find genes that share paralogs with SPATS2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SPATS2 (see all 2812)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs111689901,2
    C,H--49758938(+) ATGAAG/ATTCTC 1 -- us2k16Minor allele frequency- A:0.00NS EA NA 420
    rs1847714941,2
    --49758971(+) CTGTTC/TCTACT 1 -- us2k10--------
    rs785629031,2
    C--49758974(+) TTCCTA/GCTCTG 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1894415271,2
    --49759020(+) ACTCAC/TTCCTT 1 -- us2k10--------
    rs1823293491,2
    C--49759393(+) CTTCTA/GTTTGA 1 -- us2k10--------
    rs1420039631,2
    --49759467(+) TTCGTC/TTTCTG 1 -- us2k10--------
    rs1861252191,2
    --49759506(+) GGAGTA/GGATGA 1 -- us2k10--------
    rs1159737601,2
    C,F--49759519(+) CATTAC/TTAACC 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1163395671,2
    F--49759618(+) CTATAC/GTACTC 1 -- us2k11Minor allele frequency- G:0.04WA 118
    rs2008754881,2
    --49759621(+) TACTA-/CTCAGTTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SPATS2 (49760367 - 49921207 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SPATS2 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2678939CNV Deletion23128226
    esv2674904CNV Deletion23128226
    esv2660035CNV Deletion23128226
    esv1526240CNV Deletion17803354
    esv2675557CNV Deletion23128226
    esv2665539CNV Deletion23128226
    nsv832406CNV Loss17160897
    nsv899070CNV Loss21882294
    dgv1423n71CNV Loss21882294
    nsv518746CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SPATS2
    DNA2.0 Custom Variant and Variant Library Synthesis for SPATS2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611667    OMIM disorders: --


    Find genes that share disorders with SPATS2           About GenesLikeMe

    Genetic Association Database (GAD): SPATS2
    Human Genome Epidemiology (HuGE) Navigator: SPATS2 (1 document)

    Export disorders for SPATS2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SPATS2 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with SPATS2)
        Utopia: connect your pdf to the dynamic
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    1. Microarray analysis of bisphenol A-induced changes in gene expression in human oral epithelial cells. (PubMed id 17989879)1, 3, 9 Seki K....Ito K. (Acta Biochim. Biophys. Sin. (Shanghai) 2007)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Identification of a novel protein p59(scr), which is expressed at specific stages of mouse spermatogenesis. (PubMed id 11944913)1, 3 Senoo M....Habu S. (Biochem. Biophys. Res. Commun. 2002)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)
    9. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 65244 HGNC: 18650 AceView: SPATS2 Ensembl:ENSG00000123352 euGenes: HUgn65244
    ECgene: SPATS2 H-InvDB: SPATS2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SPATS2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SPATS2 gene:
    Search GeneIP for patents involving SPATS2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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