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Aliases for SPATS1 Gene

Aliases for SPATS1 Gene

  • Spermatogenesis Associated, Serine-Rich 1 2 3
  • SPATA8 3
  • SRSP1 3
  • DDIP 3

External Ids for SPATS1 Gene

Previous GeneCards Identifiers for SPATS1 Gene

  • GC06P044311
  • GC06P044358
  • GC06P044359
  • GC06P044418
  • GC06P044033

Summaries for SPATS1 Gene

GeneCards Summary for SPATS1 Gene

SPATS1 (Spermatogenesis Associated, Serine-Rich 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATS1 Gene

Genomics for SPATS1 Gene

Regulatory Elements for SPATS1 Gene

Genomic Location for SPATS1 Gene

44,342,660 bp from pter
44,377,167 bp from pter
34,508 bases
Plus strand

Genomic View for SPATS1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATS1 Gene

Proteins for SPATS1 Gene

  • Protein details for SPATS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated serine-rich protein 1
    Protein Accession:
    Secondary Accessions:
    • Q496A2
    • Q496A5
    • Q96LJ0

    Protein attributes for SPATS1 Gene

    300 amino acids
    Molecular mass:
    33705 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPATS1 Gene


neXtProt entry for SPATS1 Gene

Proteomics data for SPATS1 Gene at MOPED

Post-translational modifications for SPATS1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATS1 Gene

No data available for DME Specific Peptides for SPATS1 Gene

Domains & Families for SPATS1 Gene

Protein Domains for SPATS1 Gene


Suggested Antigen Peptide Sequences for SPATS1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPATS1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SPATS1 Gene

Function for SPATS1 Gene

genes like me logo Genes that share phenotypes with SPATS1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATS1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATS1 Gene

Localization for SPATS1 Gene

Subcellular locations from

Jensen Localization Image for SPATS1 Gene COMPARTMENTS Subcellular localization image for SPATS1 gene
Compartment Confidence
chloroplast 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SPATS1 Gene

Pathways & Interactions for SPATS1 Gene

SuperPathways for SPATS1 Gene

No Data Available

Interacting Proteins for SPATS1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000424400 for SPATS1 Gene via STRING

Gene Ontology (GO) - Biological Process for SPATS1 Gene


No data available for Pathways by source and SIGNOR curated interactions for SPATS1 Gene

Drugs & Compounds for SPATS1 Gene

No Compound Related Data Available

Transcripts for SPATS1 Gene

mRNA/cDNA for SPATS1 Gene

Unigene Clusters for SPATS1 Gene

Spermatogenesis associated, serine-rich 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATS1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATS1 Gene

No ASD Table

Relevant External Links for SPATS1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATS1 Gene

mRNA expression in normal human tissues for SPATS1 Gene

mRNA differential expression in normal tissues according to GTEx for SPATS1 Gene

This gene is overexpressed in Testis (x42.3).

SOURCE GeneReport for Unigene cluster for SPATS1 Gene Hs.135283

genes like me logo Genes that share expression patterns with SPATS1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPATS1 Gene

Orthologs for SPATS1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPATS1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPATS1 35
  • 82.6 (n)
  • 73.22 (a)
(Canis familiaris)
Mammalia SPATS1 35
  • 85.83 (n)
  • 80.61 (a)
  • 79 (a)
(Mus musculus)
Mammalia Spats1 35
  • 76.49 (n)
  • 69.38 (a)
Spats1 16
Spats1 36
  • 65 (a)
(Pan troglodytes)
Mammalia SPATS1 35
  • 99.22 (n)
  • 98.33 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Spats1 35
  • 75.24 (n)
  • 70.61 (a)
(Monodelphis domestica)
Mammalia SPATS1 36
  • 40 (a)
(Ornithorhynchus anatinus)
Mammalia SPATS1 36
  • 48 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100497327 35
  • 51.45 (n)
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 28 (a)
Species with no ortholog for SPATS1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATS1 Gene

Gene Tree for SPATS1 (if available)
Gene Tree for SPATS1 (if available)

Paralogs for SPATS1 Gene

No data available for Paralogs for SPATS1 Gene

Variants for SPATS1 Gene

Sequence variations from dbSNP and Humsavar for SPATS1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs867063 -- 44,357,412(-) GGAGC(A/G)AAACT intron-variant
rs883193 -- 44,342,954(-) AGCCT(C/T)ACTCC intron-variant
rs883194 -- 44,342,869(-) CTGCA(C/G)CCCCC intron-variant
rs950229 -- 44,345,596(+) TTTAC(A/G)TGCTA intron-variant
rs950230 -- 44,345,685(+) TGCAA(G/T)TATTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPATS1 Gene

Variant ID Type Subtype PubMed ID
esv2656645 CNV Deletion 23128226

Variation tolerance for SPATS1 Gene

Residual Variation Intolerance Score: 62.53% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.46; 77.38% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SPATS1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATS1 Gene

Disorders for SPATS1 Gene

Relevant External Links for SPATS1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SPATS1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATS1 Gene

Publications for SPATS1 Gene

  1. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 67
  2. Dishevelled-DEP domain interacting protein (DDIP) inhibits Wnt signaling by promoting TCF4 degradation and disrupting the TCF4/beta-catenin complex. (PMID: 20603214) Zhang H. … Chang Z. (Cell. Signal. 2010) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for SPATS1 Gene

Sources for SPATS1 Gene

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