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Aliases for SPATC1L Gene

Aliases for SPATC1L Gene

  • Spermatogenesis And Centriole Associated 1-Like 2 3
  • C21orf56 3 4 6
  • Spermatogenesis And Centriole-Associated Protein 1-Like Protein 3 4
  • Speriolin-Like Protein 2 3
  • Chromosome 21 Open Reading Frame 56 2

External Ids for SPATC1L Gene

Previous HGNC Symbols for SPATC1L Gene

  • C21orf56

Previous GeneCards Identifiers for SPATC1L Gene

  • GC21M047582

Summaries for SPATC1L Gene

GeneCards Summary for SPATC1L Gene

SPATC1L (Spermatogenesis And Centriole Associated 1-Like) is a Protein Coding gene. An important paralog of this gene is SPATC1.

Gene Wiki entry for SPATC1L Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATC1L Gene

Genomics for SPATC1L Gene

Genomic Location for SPATC1L Gene

46,161,148 bp from pter
46,184,694 bp from pter
23,547 bases
Minus strand

Genomic View for SPATC1L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATC1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATC1L Gene

No data available for Regulatory Elements for SPATC1L Gene

Proteins for SPATC1L Gene

  • Protein details for SPATC1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Speriolin-like protein
    Protein Accession:
    Secondary Accessions:
    • B4E323
    • Q52LS9
    • Q6FIH5
    • Q6P0L3
    • Q9NSE5

    Protein attributes for SPATC1L Gene

    340 amino acids
    Molecular mass:
    37613 Da
    Quaternary structure:
    No Data Available
    • Highly variable expression among individuals is associated with differential sensitivity to the DNA alkylating agent N-methyl-N-nitro-N-nitrosoguanidine (MNNG), decreased expression being associated with increased sensitivity
    • Sequence=BAA95497.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for SPATC1L Gene


neXtProt entry for SPATC1L Gene

Proteomics data for SPATC1L Gene at MOPED

Post-translational modifications for SPATC1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATC1L Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for SPATC1L Gene

Domains for SPATC1L Gene

Protein Domains for SPATC1L Gene


Graphical View of Domain Structure for InterPro Entry



  • Q9H0A9
  • Belongs to the speriolin family.
genes like me logo Genes that share domains with SPATC1L: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for SPATC1L Gene

Function for SPATC1L Gene

Gene Ontology (GO) - Molecular Function for SPATC1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with SPATC1L: view

Animal Model Products

CRISPR Products

miRNA for SPATC1L Gene

miRTarBase miRNAs that target SPATC1L

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATC1L

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SPATC1L Gene

Localization for SPATC1L Gene

Gene Ontology (GO) - Cellular Components for SPATC1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with SPATC1L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for SPATC1L Gene

Pathways for SPATC1L Gene

SuperPathways for SPATC1L Gene

No Data Available

Gene Ontology (GO) - Biological Process for SPATC1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with SPATC1L: view

No data available for Pathways by source for SPATC1L Gene

Transcripts for SPATC1L Gene

Unigene Clusters for SPATC1L Gene

Spermatogenesis and centriole associated 1-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATC1L

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATC1L Gene

No ASD Table

Relevant External Links for SPATC1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATC1L Gene

mRNA expression in normal human tissues for SPATC1L Gene

mRNA differential expression in normal tissues according to GTEx for SPATC1L Gene

This gene is overexpressed in Testis (5.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SPATC1L Gene

SOURCE GeneReport for Unigene cluster for SPATC1L Gene Hs.381214

genes like me logo Genes that share expressions with SPATC1L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SPATC1L Gene

Orthologs for SPATC1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPATC1L Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SPATC1L 35
  • 98.33 (n)
  • 97.35 (a)
  • 97 (a)
(Bos Taurus)
Mammalia C1H21ORF56 36
  • 84 (a)
  • 85.6 (n)
  • 84.62 (a)
(Canis familiaris)
Mammalia SPATC1L 35
  • 85.74 (n)
  • 80.24 (a)
  • 80 (a)
(Mus musculus)
Mammalia Spatc1l 35
  • 82.1 (n)
  • 85.55 (a)
Spatc1l 16
Spatc1l 36
  • 85 (a)
(Monodelphis domestica)
Mammalia SPATC1L 36
  • 68 (a)
(Ornithorhynchus anatinus)
Mammalia SPATC1L 36
  • 40 (a)
(Rattus norvegicus)
Mammalia Spatc1l 35
  • 82.07 (n)
  • 87.73 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 27 (a)
Species with no ortholog for SPATC1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATC1L Gene

Gene Tree for SPATC1L (if available)
Gene Tree for SPATC1L (if available)

Paralogs for SPATC1L Gene

Paralogs for SPATC1L Gene

Selected SIMAP similar genes for SPATC1L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPATC1L: view

Variants for SPATC1L Gene

Sequence variations from dbSNP and Humsavar for SPATC1L Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type MAF
rs10188 -- 46,161,305(-) TGCGC(A/G)TCCCC utr-variant-3-prime
rs14378 - 46,161,509(+) GGCTG(C/T)TGTGC missense, reference
rs884134 - 46,168,514(+) TGAAG(A/G)GTGCC reference, missense, utr-variant-5-prime
rs2040286 -- 46,169,744(+) GAGCC(C/T)CCTGC intron-variant
rs2330398 -- 46,172,099(+) GAGGC(A/G)GGAGT intron-variant

Relevant External Links for SPATC1L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SPATC1L Gene

Disorders for SPATC1L Gene

No disorders were found for SPATC1L Gene.

No data available for UniProtKB/Swiss-Prot for SPATC1L Gene

Publications for SPATC1L Gene

  1. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M. … Yaspo M.-L. (Nature 2000) 3 4
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3

Products for SPATC1L Gene

Sources for SPATC1L Gene

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