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Aliases for SPATA9 Gene

Aliases for SPATA9 Gene

  • Spermatogenesis Associated 9 2 3
  • Testis Development Protein NYD-SP16 3 4
  • Spermatogenesis-Associated Protein 9 3
  • NYD-SP16 3

External Ids for SPATA9 Gene

Previous GeneCards Identifiers for SPATA9 Gene

  • GC05M095016
  • GC05M095061
  • GC05M095013
  • GC05M090184

Summaries for SPATA9 Gene

GeneCards Summary for SPATA9 Gene

SPATA9 (Spermatogenesis Associated 9) is a Protein Coding gene.

UniProtKB/Swiss-Prot for SPATA9 Gene

  • May play a role in testicular development/spermatogenesis and may be an important factor in male infertility.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA9 Gene

Genomics for SPATA9 Gene

Regulatory Elements for SPATA9 Gene

Transcription factor binding sites by QIAGEN in the SPATA9 gene promoter:

Genomic Location for SPATA9 Gene

95,652,181 bp from pter
95,698,711 bp from pter
46,531 bases
Minus strand

Genomic View for SPATA9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATA9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA9 Gene

Proteins for SPATA9 Gene

  • Protein details for SPATA9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 9
    Protein Accession:
    Secondary Accessions:
    • A8K8H3
    • Q4G122
    • Q86X33
    • Q8NA28

    Protein attributes for SPATA9 Gene

    254 amino acids
    Molecular mass:
    28740 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPATA9 Gene


neXtProt entry for SPATA9 Gene

Proteomics data for SPATA9 Gene at MOPED

Post-translational modifications for SPATA9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA9 Gene

Antibody Products

No data available for DME Specific Peptides for SPATA9 Gene

Domains for SPATA9 Gene

Protein Domains for SPATA9 Gene


Suggested Antigen Peptide Sequences for SPATA9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPATA9: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SPATA9 Gene

Function for SPATA9 Gene

Molecular function for SPATA9 Gene

UniProtKB/Swiss-Prot Function:
May play a role in testicular development/spermatogenesis and may be an important factor in male infertility.

Animal Model Products

miRNA for SPATA9 Gene

miRTarBase miRNAs that target SPATA9

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA9

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for SPATA9 Gene

Localization for SPATA9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA9 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SPATA9 Gene COMPARTMENTS Subcellular localization image for SPATA9 gene
Compartment Confidence
cytosol 3
mitochondrion 2
endoplasmic reticulum 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for SPATA9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SPATA9: view

Pathways for SPATA9 Gene

SuperPathways for SPATA9 Gene

No Data Available

Interacting Proteins for SPATA9 Gene

Gene Ontology (GO) - Biological Process for SPATA9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007275 multicellular organismal development IEA --
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with SPATA9: view

No data available for Pathways by source for SPATA9 Gene

Transcripts for SPATA9 Gene

Unigene Clusters for SPATA9 Gene

Spermatogenesis associated 9:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA9

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA9 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP2: -
SP3: - -
SP4: - -

Relevant External Links for SPATA9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA9 Gene

mRNA expression in normal human tissues for SPATA9 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA9 Gene

This gene is overexpressed in Testis (24.1).

Protein differential expression in normal tissues for SPATA9 Gene

This gene is overexpressed in Plasma (68.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SPATA9 Gene

SOURCE GeneReport for Unigene cluster for SPATA9 Gene Hs.50499

mRNA Expression by UniProt/SwissProt for SPATA9 Gene

Tissue specificity: Highly expressed in testes and pancreas. Low levels found in the heart, lungs, and brain. Very low expression detected in the placenta. No expression seen in skeletal muscle, liver, kidney, thymus, small intestine, colons, spleen, leukocytes, prostate gland, and ovary. In the adult testes, expression was about 6.44-fold higher than in the embryo testes. No expression in testes of patients with Sertoli-cell-only syndrome. In patients with arrest at spermatogonium and primary spermatocyte stages, no expression was detected. In patients with arrest at the spermatid stage, expression level was weak or absent. Variable expression was seen in patients with spermatogenic arrest.
genes like me logo Genes that share expressions with SPATA9: view

Expression partners for SPATA9 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for SPATA9 Gene

Orthologs for SPATA9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPATA9 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPATA9 35
  • 89.95 (n)
  • 90.08 (a)
  • 90 (a)
(Canis familiaris)
Mammalia SPATA9 35
  • 90.74 (n)
  • 88.49 (a)
  • 88 (a)
(Mus musculus)
Mammalia Spata9 35
  • 82.6 (n)
  • 79.28 (a)
Spata9 16
Spata9 36
  • 79 (a)
(Pan troglodytes)
Mammalia SPATA9 35
  • 99.48 (n)
  • 99.61 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Spata9 35
  • 85.39 (n)
  • 84.06 (a)
(Monodelphis domestica)
Mammalia SPATA9 36
  • 72 (a)
(Anolis carolinensis)
Reptilia SPATA9 36
  • 39 (a)
Species with no ortholog for SPATA9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA9 Gene

Gene Tree for SPATA9 (if available)
Gene Tree for SPATA9 (if available)

Paralogs for SPATA9 Gene

No data available for Paralogs for SPATA9 Gene

Variants for SPATA9 Gene

Sequence variations from dbSNP and Humsavar for SPATA9 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs10705 -- 95,658,635(-) ATGAA(C/T)GAGCA synonymous-codon, reference, nc-transcript-variant, intron-variant
rs34895 -- 95,682,678(-) ATGTT(A/C)TTTTG intron-variant
rs34901 -- 95,668,779(+) TAAAA(C/G)AAGTA intron-variant
rs34902 -- 95,670,335(-) GAAAC(A/G)AAGAA intron-variant
rs40098 -- 95,683,815(+) tacag(A/G)tgtga upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SPATA9 Gene

Variant ID Type Subtype PubMed ID
nsv507274 CNV Insertion 20534489
esv2513210 CNV Insertion 19546169
esv273462 CNV Insertion 20981092
esv267864 CNV Insertion 20981092
esv1052640 CNV Insertion 17803354
nsv830409 CNV Gain 17160897

Relevant External Links for SPATA9 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA9 Gene

Disorders for SPATA9 Gene

Relevant External Links for SPATA9

Genetic Association Database (GAD)

No disorders were found for SPATA9 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SPATA9 Gene

Publications for SPATA9 Gene

  1. NYD-SP16, a novel gene associated with spermatogenesis of human testis. (PMID: 12493713) Cheng L.J. … Sha J.H. (Biol. Reprod. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. (PMID: 21946350) Soler Artigas M. … Tobin M.D. (Nat. Genet. 2011) 3 48
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SPATA9 Gene

Sources for SPATA9 Gene

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