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Aliases for SPATA8 Gene

Aliases for SPATA8 Gene

  • Spermatogenesis Associated 8 2 3
  • Spermatogenesis-Related Protein 8 3 4
  • SRG8 3 6
  • Spermatogenesis-Associated Protein 8 3

External Ids for SPATA8 Gene

Previous GeneCards Identifiers for SPATA8 Gene

  • GC15P095128
  • GC15P097326
  • GC15P073456

Summaries for SPATA8 Gene

GeneCards Summary for SPATA8 Gene

SPATA8 (Spermatogenesis Associated 8) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA8 Gene

Genomics for SPATA8 Gene

Regulatory Elements for SPATA8 Gene

Genomic Location for SPATA8 Gene

Start:
96,783,389 bp from pter
End:
96,785,615 bp from pter
Size:
2,227 bases
Orientation:
Plus strand

Genomic View for SPATA8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATA8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA8 Gene

Proteins for SPATA8 Gene

  • Protein details for SPATA8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6RVD6-SPAT8_HUMAN
    Recommended name:
    Spermatogenesis-associated protein 8
    Protein Accession:
    Q6RVD6
    Secondary Accessions:
    • Q2KJ07

    Protein attributes for SPATA8 Gene

    Size:
    105 amino acids
    Molecular mass:
    11727 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPATA8 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SPATA8 Gene

Proteomics data for SPATA8 Gene at MOPED

Post-translational modifications for SPATA8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA8 Gene

No data available for DME Specific Peptides for SPATA8 Gene

Domains for SPATA8 Gene

Protein Domains for SPATA8 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for SPATA8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPATA8: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SPATA8 Gene

Function for SPATA8 Gene

Gene Ontology (GO) - Molecular Function for SPATA8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
genes like me logo Genes that share ontologies with SPATA8: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA8

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SPATA8 Gene

Localization for SPATA8 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SPATA8 Gene COMPARTMENTS Subcellular localization image for SPATA8 gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SPATA8 Gene

Pathways for SPATA8 Gene

SuperPathways for SPATA8 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SPATA8 Gene

None

No data available for Pathways by source for SPATA8 Gene

Transcripts for SPATA8 Gene

Unigene Clusters for SPATA8 Gene

Spermatogenesis associated 8:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA8

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SPATA8
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA8 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c
SP1: -
SP2:
SP3: - -

Relevant External Links for SPATA8 Gene

GeneLoc Exon Structure for
SPATA8
ECgene alternative splicing isoforms for
SPATA8

Expression for SPATA8 Gene

mRNA expression in normal human tissues for SPATA8 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA8 Gene

This gene is overexpressed in Testis (52.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SPATA8 Gene

SOURCE GeneReport for Unigene cluster for SPATA8 Gene Hs.326528

mRNA Expression by UniProt/SwissProt for SPATA8 Gene

Q6RVD6-SPAT8_HUMAN
Tissue specificity: Expressed at high levels in adult testis, at moderate levels in sperm and at low levels in fetal testis. Not detected in other tissues.
genes like me logo Genes that share expressions with SPATA8: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for SPATA8 Gene

Orthologs for SPATA8 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for SPATA8 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SPATA8 35
  • 99.37 (n)
  • 98.1 (a)
SPATA8 36
  • 98 (a)
OneToOne
Species with no ortholog for SPATA8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA8 Gene

ENSEMBL:
Gene Tree for SPATA8 (if available)
TreeFam:
Gene Tree for SPATA8 (if available)

Paralogs for SPATA8 Gene

Pseudogenes.org Pseudogenes for SPATA8 Gene

genes like me logo Genes that share paralogs with SPATA8: view

No data available for Paralogs for SPATA8 Gene

Variants for SPATA8 Gene

Sequence variations from dbSNP and Humsavar for SPATA8 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs12904027 -- 96,785,636(+) TTTTT(G/T)TTTGT downstream-variant-500B
rs28552478 -- 96,786,059(+) AGGCT(A/C)TACTA downstream-variant-500B
rs58524687 -- 96,785,639(+) TTTTT(-/T/TTT)GTTTG downstream-variant-500B
rs62023894 -- 96,785,645(+) GTTTG(G/T)TTGTT downstream-variant-500B
rs74350828 -- 96,785,653(+) GTTTT(-/TTTT)CTGAA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for SPATA8 Gene

Variant ID Type Subtype PubMed ID
nsv522924 CNV Gain 19592680
nsv904533 CNV Loss 21882294

Relevant External Links for SPATA8 Gene

HapMap Linkage Disequilibrium report
SPATA8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA8 Gene

Disorders for SPATA8 Gene

Relevant External Links for SPATA8

Genetic Association Database (GAD)
SPATA8
genes like me logo Genes that share disorders with SPATA8: view

No data available for UniProtKB/Swiss-Prot for SPATA8 Gene

Publications for SPATA8 Gene

  1. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PMID: 18951430) Anney R.J. … Gill M. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008) 3 48
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Molecular cloning and characterization of a novel human testis- specific gene by use of digital differential display. (PMID: 16809841) Nie D. … Xiang Y. (J. Genet. 2006) 3 4
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SPATA8 Gene

Sources for SPATA8 Gene

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