SPATA8 Gene
protein-coding GIFtS: 38
GCID: GC15P097326
|
|
spermatogenesis associated 8
| |
Aliases
for SPATA8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Spermatogenesis Associated 81 2 | | Spermatogenesis-Related Protein 82 3 | | MGC442941 | | SRG82 | | Spermatogenesis-Associated Protein 82 |
Export aliases for SPATA8 gene to outside databasesPrevious GC identifers: GC15P095128 GC15P073456 |
Summaries
for SPATA8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SPATA8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SPATA8 gene promoter:
Oct-B1 GR oct-B3 oct-B2 AML1a GR-beta HTF AREB6 POU2F1 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for SPATA8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPATA8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q26.2 Ensembl cytogenetic band: 15q26.2 HGNC cytogenetic band: 15q26SPATA8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P097326: view genomic region
(about GC identifiers)
Start:
|
97,326,619 bp from pter |
End:
|
97,328,845 bp from pter |
Size:
|
2,227 bases |
Orientation:
|
plus strand |
|
Proteins
for SPATA8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SPAT8_HUMAN, Q6RVD6 (See
protein sequence)Recommended Name: Spermatogenesis-associated protein 8 Size: 105 amino acids; 11727 Da
Secondary accessions: Q2KJ07Alternative splicing: 2 isoforms: Q6RVD6-1 Q6RVD6-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SPATA8: NX_Q6RVD6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6RVD6
SPATA8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_775770.1
ENSEMBL proteins: ENSP00000328149 ENSP00000453026
Human Recombinant Protein Products:
SPATA8 Antibody Products:
Assay Products for SPATA8: |
Protein
Domains /
Families
for SPATA8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6RVD6 |
Function
for SPATA8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA8
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SPATA8 (NM_173499) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPATA8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA8 |
|
Pathways & Interactions
for SPATA8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SPATA8
1 Interacting protein for SPATA8 (Q6RVD63) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for SPATA8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SPATA8
Search CenterWatch for drugs/clinical trials and news about SPATA8 / SPAT8
|
Transcripts
for SPATA8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SPATA8 gene: NM_173499.3 Unigene Cluster for SPATA8: Spermatogenesis associated 8 Hs.326528 [show with all ESTs]Unigene Representative Sequence: BC1123904 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000328504(uc002bue.3) ENST00000561002 ENST00000558553 ENST00000560327
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA8
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SPATA8 (NM_173499) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPATA8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA8 |
Additional cDNA sequence: AY489187.1 BC033979.2 BC066292.1 BC112390.1 4 DOTS entries: DT.209645 DT.92012669 DT.100748414 DT.100748413 24/46 AceView cDNA sequences (see all 46): AW293729 BM553033 AA399652 BC033979 AW274919 BI825473 AA398750 BI831484 AA292849 BI559387 BC066292 AI336937 BG722505 CD243868 AA861167 BI825859 AI638541 AI917479 AI916811 BI827393 AI014962 AI953138 BI461476 BI825151
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for SPATA8 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for SPATA8
|
Expression
for SPATA8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SPATA8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACTTTTCTG
About this image
See SPATA8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SPATA8
SOURCE GeneReport for Unigene cluster: Hs.326528
UniProtKB/Swiss-Prot: SPAT8_HUMAN, Q6RVD6Tissue specificity: Expressed at high levels in adult testis, at moderate levels in sperm and at low levels in fetaltestis. Not detected in other tissues
SABiosciences Custom PCR Arrays for SPATA8
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPATA8
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SPATA8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA8 |
Orthologs
for SPATA8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for SPATA8 (if available)
TreeFam Gene Tree for SPATA8 (if available) |
Paralogs
for SPATA8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SPATA8 gene
SPATA8 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for SPATA8
PGOHUM00000262114
|
Genomic Variants
for SPATA8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SPATA8 (97326619 - 97328845 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SPATA8: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPATA8 |
|
Disorders
/ Diseases
for SPATA8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SPATA8 for disorders About GeneDecksing
OMIM gene information: 613948
OMIM disorders: --
2  diseases for SPATA8: About MalaCardsconduct disorder adhd
Export disorders for SPATA8 gene to outside databases
|
Publications
for SPATA8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SPATA8 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SPATA8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and characterization of a novel hum an testis-specific gene by use of digital differential display. (PubMed id 16809841)1, 2 Nie D. and Xiang Y. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PubMed id 18951430)1 Anney R.J....Gill M. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for SPATA8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SPATA8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SPATA8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SPATA8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SPATA8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SPATA8 gene:
Search GeneIP for patents involving SPATA8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SPATA8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SPATA8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SPATA8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPATA8 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SPATA8 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SPATA8 | | OriGene Custom Protein Services for SPATA8 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPATA8 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPATA8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPATA8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPATA8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA8 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SPATA8 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | SPATA8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA8 |
|  |  |  | | | | Search ThermoFisher Antibodies for SPATA8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA8 |
|
|
|
|
