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Aliases for SPATA6L Gene

Aliases for SPATA6L Gene

  • Spermatogenesis Associated 6 Like 2 3
  • C9orf68 3 4
  • Chromosome 9 Open Reading Frame 68 2
  • Spermatogenesis Associated 6-Like 5
  • BA6J24.2 3

External Ids for SPATA6L Gene

Previous HGNC Symbols for SPATA6L Gene

  • C9orf68

Summaries for SPATA6L Gene

GeneCards Summary for SPATA6L Gene

SPATA6L (Spermatogenesis Associated 6 Like) is a Protein Coding gene. An important paralog of this gene is SPATA6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA6L Gene

Genomics for SPATA6L Gene

Regulatory Elements for SPATA6L Gene

Promoters for SPATA6L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SPATA6L on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA6L Gene

4,553,386 bp from pter
4,666,801 bp from pter
113,416 bases
Minus strand

Genomic View for SPATA6L Gene

Genes around SPATA6L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA6L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA6L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA6L Gene

Proteins for SPATA6L Gene

  • Protein details for SPATA6L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis associated 6-like protein
    Protein Accession:
    Secondary Accessions:
    • B4DIY4
    • Q5JVJ5
    • Q8IY90

    Protein attributes for SPATA6L Gene

    392 amino acids
    Molecular mass:
    45058 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPATA6L Gene


neXtProt entry for SPATA6L Gene

Proteomics data for SPATA6L Gene at MOPED

Post-translational modifications for SPATA6L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA6L Gene

No data available for DME Specific Peptides for SPATA6L Gene

Domains & Families for SPATA6L Gene

Protein Domains for SPATA6L Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATA6 family.
  • Belongs to the SPATA6 family.
genes like me logo Genes that share domains with SPATA6L: view

No data available for Gene Families for SPATA6L Gene

Function for SPATA6L Gene

Phenotypes for SPATA6L Gene

GenomeRNAi human phenotypes for SPATA6L:
genes like me logo Genes that share phenotypes with SPATA6L: view

Animal Model Products

CRISPR Products

miRNA for SPATA6L Gene

miRTarBase miRNAs that target SPATA6L

miRNA Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SPATA6L Gene

Localization for SPATA6L Gene

Subcellular locations from

Jensen Localization Image for SPATA6L Gene COMPARTMENTS Subcellular localization image for SPATA6L gene
Compartment Confidence
nucleus 3
cytosol 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SPATA6L Gene

Pathways & Interactions for SPATA6L Gene

SuperPathways for SPATA6L Gene

No Data Available

Interacting Proteins for SPATA6L Gene

Gene Ontology (GO) - Biological Process for SPATA6L Gene


No data available for Pathways by source and SIGNOR curated interactions for SPATA6L Gene

Drugs & Compounds for SPATA6L Gene

No Compound Related Data Available

Transcripts for SPATA6L Gene

Unigene Clusters for SPATA6L Gene

Spermatogenesis associated 6-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA6L Gene

No ASD Table

Relevant External Links for SPATA6L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA6L Gene

mRNA expression in normal human tissues for SPATA6L Gene

mRNA differential expression in normal tissues according to GTEx for SPATA6L Gene

This gene is overexpressed in Liver (x4.6) and Testis (x4.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA6L Gene

SOURCE GeneReport for Unigene cluster for SPATA6L Gene Hs.179615

genes like me logo Genes that share expression patterns with SPATA6L: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPATA6L Gene

Orthologs for SPATA6L Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPATA6L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPATA6L 35
  • 85.53 (n)
  • 76.05 (a)
  • 62 (a)
(Canis familiaris)
Mammalia SPATA6L 35
  • 85.43 (n)
  • 76.95 (a)
  • 60 (a)
(Pan troglodytes)
Mammalia SPATA6L 35
  • 99.3 (n)
  • 99.1 (a)
  • 88 (a)
(Monodelphis domestica)
Mammalia SPATA6L 36
  • 26 (a)
(Mus musculus)
Mammalia 4430402I18Rik 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 11 (a)
(Anolis carolinensis)
Reptilia SPATA6L 36
  • 26 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.10830 35
(Danio rerio)
Actinopterygii -- 35
spata6l 36
  • 22 (a)
Species with no ortholog for SPATA6L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SPATA6L Gene

Gene Tree for SPATA6L (if available)
Gene Tree for SPATA6L (if available)

Paralogs for SPATA6L Gene

Paralogs for SPATA6L Gene

(1) SIMAP similar genes for SPATA6L Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with SPATA6L: view

Variants for SPATA6L Gene

Sequence variations from dbSNP and Humsavar for SPATA6L Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10974657 - 4,622,453(+) TCTTC(C/T)AGACC nc-transcript-variant, reference, missense
rs16921613 - 4,617,990(+) TGAAG(C/T)TTTCC intron-variant, nc-transcript-variant, downstream-variant-500B, reference, missense
rs2771 -- 4,598,379(+) TCACA(A/G)AATTA intron-variant, nc-transcript-variant, utr-variant-3-prime
rs586725 -- 4,653,924(+) agagc(C/G)agacc intron-variant
rs364802 -- 4,644,979(+) caaat(C/G/T)tactc intron-variant

Variation tolerance for SPATA6L Gene

Residual Variation Intolerance Score: 93.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.76; 83.23% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SPATA6L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SPATA6L Gene

Disorders for SPATA6L Gene

Relevant External Links for SPATA6L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPATA6L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA6L Gene

Publications for SPATA6L Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Genetics of coronary artery calcification among African Americans, a meta-analysis. (PMID: 23870195) Wojczynski M.K. … Reilly M.P. (BMC Med. Genet. 2013) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for SPATA6L Gene

Sources for SPATA6L Gene

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